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AAK1 serine/threonine kinase is a member of the NAK family and plays a regulatory role in endocytosis. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
5530400K14Rik; 9630042K20; Aak1; Adaptor-associated kinase 1; AP2 associated kinase 1; AP2-associated protein kinase 1; AU067724; AU067726; BC028270; C79663; D6Ertd245e; DKFZp686F03202; DKFZp686K16132; FLJ23712; FLJ25931; FLJ31060; FLJ42882; FLJ45252; KIAA1048; MGC138170; MGC164568; MGC164570; mKIAA1048; R75501; RGD1563580
50 µg
50 µg