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Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. [UniProt]
2900053G10Rik; 4930431N21Rik; 6530406M24Rik; Agbl3; ATP/GTP binding protein like 3; ATP/GTP binding protein-like 3; ATP/GTP-binding protein-like 3; CBCP3; CCP3; Cytosolic carboxypeptidase 3; RGD1561995
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100 µL