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Immunogen sequence: CPEPVYIPTG LETQPLYPDS KEATVVYLAE DAYKEPCFVY SRVGGNRTPL KQPVDYRDNT LMFEARFESG NLQKVVKVAE YEY
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 86%.
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP/GTP binding protein-like 3; ATP/GTP-binding protein-like 3; CBCP3; Cytosolic carboxypeptidase 3; Protein deglutamylase CCP3
基因别名: AGBL3; CCP3
UniProt ID: (Human) Q8NEM8
Entrez Gene ID: (Human) 340351
分子生物学功能: metalloprotease