Antibodies that detect DR6 can be used in several scientific applications, including ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target DR6 in Human, Mouse and Rat samples. Our DR6 monoclonal, polyclonal and recombinant monoclonal antibodies...Antibodies that detect DR6 can be used in several scientific applications, including ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target DR6 in Human, Mouse and Rat samples. Our DR6 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the...Antibodies that detect DR6 can be used in several scientific applications, including ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target DR6 in Human, Mouse and Rat samples. Our DR6 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the DR6 antibody that fits your needs. Choose from 1 of 39 DR6 antibodies, which have been validated in experiments with 1 publication and 18 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the...
Antibodies that detect DR6 can be used in several scientific applications, including ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. These antibodies target DR6 in Human, Mouse and Rat samples. Our DR6 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. Find the DR6 antibody that fits your needs. Choose from 1 of 39 DR6 antibodies, which have been validated in experiments with 1 publication and 18 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
同义词
AA959878; BM-018; CD358; Death receptor 6; Death receptor-6; DR6; MGC31965; R74815; sCD358; sDR6; soluble CD358; soluble DR6; TNF receptor superfamily member 21; TNFR-related death receptor 6; TNFR-related death receptor-6; Tnfrsf21; TR7; Tumor necrosis factor receptor superfamily member 21; tumor necrosis factor receptor superfamily, member 21; UNQ437/PRO868
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