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This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
2610035C18Rik; 2610104C07Rik; 2610312F07Rik; 3'-5' exoribonuclease CSL4 homolog; AI447561; CGI-108; CSL4; Csl4p; EXOSC1; exosomal core protein CSL4; exosome complex component CSL4; Exosome component 1; hCsl4p; homolog of yeast exosomal core protein CSL4; p13; RP11-452K12.9; SKI4; Ski4p
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