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The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme.
AW111792; Dimethylaniline monooxygenase [N-oxide-forming] 3; dimethylaniline oxidase 3; dJ127D3.1; flavin containing dimethylaniline monoxygenase 3; flavin containing monooxygenase 3; flavin-containing monooxygenase 3; flavin-containing monooxygenase FMO3; FM03; FMO 1D1; FMO 3; FMO form 2; FMO II; FMO3; FMOII; hepatic flavin-containing monooxygenase 3; hepatic flavin-containing monooxygenase-3; MGC34400; TMAU; Trimethylamine monooxygenase; Unknown (protein for MGC:128044)
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