Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%
The mammalian flavin-containing monooxygenases (FMO; EC 1.14.13.8) represent a multigene family whose gene products are localized in the endoplasmic reticulum of many tissues. These enzymes catalyze the NADPH-dependent oxidative metabolism of many drugs, pesticides, and other foreign compounds. Their substrates are soft nucleophiles with an electron-rich center, typically a nitrogen, sulfur or phosphorus-containing functional group, as the site for oxidative attack by the enzyme.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; Flavin-containing monooxygenase 3; FMO 3; Hepatic flavin-containing monooxygenase 3; MGC34400; Trimethylamine monooxygenase
基因别名: AW111792; Fmo3
UniProt ID: (Mouse) P97501
Entrez Gene ID: (Mouse) 14262
分子生物学功能: oxidoreductase oxygenase metabolite interconversion enzyme