Search Thermo Fisher Scientific
MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many musclespecific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to represses MyoD activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.
ABF1; ABF-1; Activated B-cell factor 1; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; Musculin; myogenic repressor; Myor
100 µL
100 µL
50 µg
100 µg
100 µL
100 µL
100 µg
100 µL
100 µL
100 µg