Antibodies that detect SHC can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target SHC in Human, Mouse, Rat and Non-human primate samples. Our SHC polyclonal and...Antibodies that detect SHC can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target SHC in Human, Mouse, Rat and Non-human primate samples. Our SHC polyclonal and monoclonal antibodies are developed...Antibodies that detect SHC can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target SHC in Human, Mouse, Rat and Non-human primate samples. Our SHC polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment and Knockout to confirm specificity to SHC. Find the SHC antibody that fits your needs. Choose from 1 of 45 SHC antibodies, which have been validated in experiments with 6 publications and 152 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced...
Antibodies that detect SHC can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target SHC in Human, Mouse, Rat and Non-human primate samples. Our SHC polyclonal and monoclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment and Knockout to confirm specificity to SHC. Find the SHC antibody that fits your needs. Choose from 1 of 45 SHC antibodies, which have been validated in experiments with 6 publications and 152 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Skp2 (S-phase Kinase-associated Protein 2) belongs to the family of F-box proteins that interact with the Cyclin A-Cdk2 complex. Skp2 is essential for the G1-S transition in both transformed cells and diploid fibroblasts. Biochemical and genetic experiments have demonstrated that Skp2 is required for the ubiquitination and consequent degradation of p27 in cultured mammalian cells and in vitro reconstitution assays. In normal tissues, Skp2 is expressed in tonsil and placenta. In tumor tissues, Skp2 is expressed widely, in some colon, prostate, pancreas, and skin cancers, with high expression in lung, breast, ovarian, and endometrial cancers. Research suggests that Skp2 plays a role in oncogenesis, particularly in the pathogenesis of lymphomas and breast cancers.
同义词
FLJ26504; OTTHUMP00000035472; p66; P66shc; RP11-307C12.1; SH2 domain protein C1; SHC; SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1; SHC adaptor protein 1; SHC1; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; src homology 2 domain-containing transforming protein C1; src homology 2 domain-containing-transforming protein C1
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