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产品信息
12114-1-AP
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AP3M1 Fusion Protein Ag2759 (219-418 aa encoded by BC026232)
偶联物
Unconjugated
形式
Liquid
浓度
0.17 mg/mL
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SLSFMNPRL LDDVSFHPCI RFKRWESERV LSFIPPDGNF RLISYRVSSQ NLVAIPVYVK HSISFKENSS CGRFDITIGP KQNMGKTIEG ITVTVHMPKV VLNMNLTPTQ GSYTFDPVTK VLTWDVGKIT PQKLPSLKGL VNLQSGAPKP EENPSLNIQF KIQQLAISGL KVNRLDMYGE KYKPFKGVKY VTKAGKFQVR T (219-418 aa encoded by BC026232)
靶标信息
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38. AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
