Invitrogen

CD11b Monoclonal Antibody (M1/70), FITC, eBioscience™

图: 1 / 99

CD11b Antibody (11-0112-41) in Flow

Biology 2022 - Figure 4 TIM3-positive macrophages were recruited to ATC xenograft tumors. ( A ) I. Upper panel: TIM3 mRNA expression in RAW264.7 cells and in ATC xenografts. Total RNA was isolated, and the mRNA expression of TIM3 was examined by RT-PCR analysis. Lane 1, RAW264.7 cells; lanes 2-4, 8505C xenograft tumors ( n = 3); lanes 5-7, C643 xenograft tumors ( n = 3). The lower panel represents the expression of actin.... View More

CD11b Antibody in Immunohistochemistry, Flow Cytometry (IHC, Flow)

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产品信息

11-0112-41

应用

建议稀释比

已发表文章

免疫印迹 (WB)

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免疫组化 (IHC)

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免疫组织化学（多聚甲醛固定） (IHC (PFA))

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免疫组化（冰冻） (IHC (F))

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免疫细胞化学 (ICC/IF)

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流式细胞分析 (Flow)

5 µL (0.25 µg)/test

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免疫沉淀 (IP)

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中和实验 (Neu)

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产品规格

种属反应

Mouse

已发表种属

Ferret, Fish, Human, Mouse

宿主/亚型

Rat / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

M1/70

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

5 µL/Test

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2, with 0.2% BSA

内含物

0.09% sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_11042156

产品详细信息

Description: The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.

Applications Reported: The M1/70 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This product has been pre-titrated and tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.

Filtration: 0.2 µm post-manufacturing filtered.

靶标信息

CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Product References

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Exogenous IL-10 posttreatment along with TLR4 and TNFR1 blockade improves tissue antioxidant status by modulating sepsis-induced macrophage polarization.

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Gene deletion of long-chain acyl-CoA synthetase 4 attenuates xenobiotic chemical-induced lung injury via the suppression of lipid peroxidation.

Redox biology

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Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop.

Journal of nanobiotechnology

Qiu W,Guo Q,Guo X,Wang C,Li B,Qi Y,Wang S,Zhao R,Han X,Du H,Zhao S,Pan Z,Fan Y,Wang Q,Gao Z,Li G,Xue H

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The Cxcr2⁺ subset of the S100a8⁺ gastric granylocytic myeloid-derived suppressor cell population (G-MDSC) regulates gastric pathology.

Frontiers in immunology

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Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.

iScience

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Fri Oct 20 00:00:00 EDT 2023

Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.

Nature communications

Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I

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LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.

Journal for immunotherapy of cancer

Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H

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Wed Mar 01 00:00:00 EST 2023

NLRP12-expressing dendritic cells mediate both dissemination of infection and adaptive immune responses in visceral leishmaniasis.

iScience

Valadares DG,Clay OS,Chen Y,Scorza BM,Cassel SL,Sutterwala FS,Wilson ME

11-0112-41 was used in Flow Cytometry /test) to hypothesize that Nlrp12-expressing DCs are required for efficient dissemination and immune clearance of L. infantum from the site of initial infection.

Fri Mar 17 00:00:00 EDT 2023

Topical Diacerein Decreases Skin and Splenic CD11c⁺ Dendritic Cells in Psoriasis.

International journal of molecular sciences

Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V

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Tue Feb 21 00:00:00 EST 2023

CD11c⁺ microglia promote white matter repair after ischemic stroke.

Cell death & disease

Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M

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Fri Feb 24 00:00:00 EST 2023

Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J

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Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1^highCD11b⁺ cells elimination in hepatocellular carcinoma.

Acta pharmaceutica Sinica. B

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Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.

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Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ.

Cancers

Spella M,Ntaliarda G,Skiadas G,Lamort AS,Vreka M,Marazioti A,Lilis I,Bouloukou E,Giotopoulou GA,Pepe MAA,Weiss SAI,Petrera A,Hauck SM,Koch I,Lindner M,Hatz RA,Behr J,Arendt KAM,Giopanou I,Brunn D,Savai R,Jenne DE,de Château M,Yull FE,Blackwell TS,Stathopoulos GT

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Mon Mar 20 00:00:00 EDT 2023

Metabolic improvement and liver regeneration by inhibiting CXXC5 function for non-alcoholic steatohepatitis treatment.

Experimental & molecular medicine

Seo SH,Kim E,Yoon M,Lee SH,Park BH,Choi KY

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Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis.

Nature communications

Dai B,Xu J,Li X,Huang L,Hopkins C,Wang H,Yao H,Mi J,Zheng L,Wang J,Tong W,Chow DH,Li Y,He X,Hu P,Chen Z,Zu H,Li Y,Yao Y,Jiang Q,Qin L

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Jan 20 00:00:00 EST 2022

PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.

Nature communications

Schmid MC,Kang SW,Chen H,Paradise M,Ghebremedhin A,Kaneda MM,Chin SM,Do A,Watterson DM,Varner JA

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Fri Apr 01 00:00:00 EDT 2022

Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.

PLoS neglected tropical diseases

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Frontiers in pharmacology

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Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity.

Nature communications

Franklin R,Guo Y,He S,Chen M,Ji F,Zhou X,Frankhouser D,Do BT,Chiem C,Jang M,Blanco MA,Vander Heiden MG,Rockne RC,Ninova M,Sykes DB,Hochedlinger K,Lu R,Sadreyev RI,Murn J,Volk A,Cheloufi S

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Fri Apr 29 00:00:00 EDT 2022

Biocompatible reduced graphene oxide stimulated BMSCs induce acceleration of bone remodeling and orthodontic tooth movement through promotion on osteoclastogenesis and angiogenesis.

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TPGS-based and S-thanatin functionalized nanorods for overcoming drug resistance in Klebsiella pneumonia.

Nature communications

Wang X,Xu X,Zhang S,Chen N,Sun Y,Ma K,Hong D,Li L,Du Y,Lu X,Jiang S

11-0112-41 was used in Flow cytometry/Cell sorting to design a D-alpha tocopheryl polyethylene glycol succinate-modified and S-thanatin peptide-functionalized nanorods based on calcium phosphate nanoparticles for tigecycline delivery and pneumonia therapy caused by tigecycline-resistant Klebsiella pneumoniae.

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Influence of the Postmortem/Storage Time of Human Corneas on the Properties of Cultured Limbal Epithelial Cells.

Cells

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Single-cell transcriptomics reveals distinct cell response between acute and chronic pulmonary infection of Pseudomonas aeruginosa.

MedComm

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Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

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Cirsilineol Treatment Attenuates PM_2.5-Induced Lung Injury in Mice.

International journal of molecular sciences

Kim C,Kim GO,Bae JS

11-0112-41 was used in Flow cytometry/Cell sorting to test the efficacy of cirsilineol on PM2.5-induced lung toxicity.

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Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer's Disease.

International journal of molecular sciences

Martínez-Iglesias O,Naidoo V,Carrera I,Cacabelos R

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Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.

Cell host & microbe

Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F

11-0112 was used in Flow cytometry/Cell sorting to characterize the nature of the early innate immune responses evoked in rhesus macaques and mice during SARS-CoV-2 infection.

Wed Feb 10 00:00:00 EST 2021

Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.

Cell host & microbe

Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F

11-0112 was used in Flow cytometry/Cell sorting to characterize the nature of the early innate immune responses evoked in rhesus macaques and mice during SARS-CoV-2 infection.

Wed Feb 10 00:00:00 EST 2021

A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis.

Biomaterials

Keum H,Kim D,Kim J,Kim TW,Whang CH,Jung W,Jon S

11-0112-41 was used in Flow Cytometry to report the therapeutic potential of nanoparticles derived from the endogenous antioxidant and anti-inflammatory bile acid, bilirubin (BRNPs), in treating pulmonary fibrosis in a bleomycin-induced mouse model of the disease.

Sun Aug 01 00:00:00 EDT 2021

Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.

Cell death and differentiation

Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH

11-0112 was used in Flow cytometry/Cell sorting to discover that intravitreal MSCT counteracted photoreceptor apoptosis and alleviate retinal morphological and functional degeneration in a mouse model of photoreceptor loss induced by N-methyl-N-nitrosourea (MNU).

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Short and dysfunctional telomeres protect from allergen-induced airway inflammation.

Aging cell

Piñeiro-Hermida S,Martínez P,Blasco MA

11-0112-41 was used in Flow Cytometry to study the implication of short and dysfunctional telomeres in asthma pathobiology.

Sat May 01 00:00:00 EDT 2021

Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia-induced pulmonary hypertension.

British journal of pharmacology

Wang L,Zhang X,Cao Y,Ma Q,Mao X,Xu J,Yang Q,Zhou Y,Lucas R,Fulton DJ,Su Y,Barman SA,Hong M,Liu Z,Huo Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

Depletion of Adipocyte Becn1 Leads to Lipodystrophy and Metabolic Dysregulation.

Diabetes

Jin Y,Ji Y,Song Y,Choe SS,Jeon YG,Na H,Nam TW,Kim HJ,Nahmgoong H,Kim SM,Kim JW,Nam KT,Seong JK,Hwang D,Park CB,Lee IH,Kim JB,Lee HW

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Fri Jan 01 00:00:00 EST 2021

The effects of postmortem delay on mouse and human microglia gene expression.

Glia

Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Apr 01 00:00:00 EDT 2021

Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.

Glia

Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Mar 01 00:00:00 EST 2021

CD36 deficiency ameliorates drug-induced acute liver injury in mice.

Molecular medicine (Cambridge, Mass.)

Zhang C,Shi X,Su Z,Hu C,Mu X,Pan J,Li M,Teng F,Ling T,Zhao T,Xu C,Ji G,You Q

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Jun 06 00:00:00 EDT 2021

CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages.

Immune network

Sim H,Jeong D,Kim HI,Pak S,Thapa B,Kwon HJ,Lee K

11-0112-41 was used in Flow Cytometry to delineate the role of integrin CD11b in activation and functional polarization of macrophages against pathogenic microbes in respect to sepsis susceptibility.

Thu Apr 01 00:00:00 EDT 2021

IL-1α Mediates Innate and Acquired Resistance to Immunotherapy in Melanoma.

Journal of immunology (Baltimore, Md. : 1950)

Singh S,Xiao Z,Bavisi K,Roszik J,Melendez BD,Wang Z,Cantwell MJ,Davis RE,Lizee G,Hwu P,Neelapu SS,Overwijk WW,Singh M

11-0112-41 was used in Flow Cytometry to suggest that blocking the IL-1α signaling pathway may increase the efficacy of immunotherapies against melanoma.

Thu Apr 15 00:00:00 EDT 2021

Light Environment Influences Developmental Programming of the Metabolic and Visual Systems in Mice.

Investigative ophthalmology & visual science

Clarkson-Townsend DA,Bales KL,Marsit CJ,Pardue MT

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Thu Apr 01 00:00:00 EDT 2021

Construction of a 3D brain extracellular matrix model to study the interaction between microglia and T cells in co-culture.

The European journal of neuroscience

Frühauf M,Zeitschel U,Höfling C,Ullm F,Rabiger FV,Alber G,Pompe T,Müller U,Roßner S

11-0112 was used in Flow cytometry/Cell sorting to indicate that biomimetic 3D matrices allow for co-cultivation and activation of primary microglia and T cells and provide useful tools to study their interaction in vitro.

Tue Jun 01 00:00:00 EDT 2021

Advanced maternal age induces fetal growth restriction through decreased placental inflammatory cytokine expression and immune cell accumulation in mice.

The Journal of reproduction and development

Hirata Y,Katsukura Y,Henmi Y,Ozawa R,Shimazaki S,Kurosawa A,Torii Y,Takahashi H,Iwata H,Kuwayama T,Shirasuna K

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Aug 27 00:00:00 EDT 2021

Effect of IL-33 on pyroptosis of macrophages in mice with sepsis via NF-κB/p38 MAPK signaling pathway.

Acta cirurgica brasileira

Ke J,Cai G

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry (PFA fixed)

Fri Jun 18 00:00:00 EDT 2021

Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages.

JCI insight

Hu X,Dong X,Li G,Chen Y,Chen J,He X,Sun H,Kim DH,Kemper JK,Chen LF

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Apr 08 00:00:00 EDT 2021

Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.

Cells

Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Nov 15 00:00:00 EST 2021

Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.

Cellular and molecular gastroenterology and hepatology

Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Mar 28 00:00:00 EDT 2022

Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.

Aging

Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jul 21 00:00:00 EDT 2021

Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.

Nature communications

Fujino T,Goyama S,Sugiura Y,Inoue D,Asada S,Yamasaki S,Matsumoto A,Yamaguchi K,Isobe Y,Tsuchiya A,Shikata S,Sato N,Morinaga H,Fukuyama T,Tanaka Y,Fukushima T,Takeda R,Yamamoto K,Honda H,Nishimura EK,Furukawa Y,Shibata T,Abdel-Wahab O,Suematsu M,Kitamura T

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Mar 23 00:00:00 EDT 2021

In vitro and ex vivo evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse.

STAR protocols

Zeng W,Yin X,Jiang Y,Jin L,Liang W

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Mar 19 00:00:00 EDT 2021

Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Tan H,Song Y,Chen J,Zhang N,Wang Q,Li Q,Gao J,Yang H,Dong Z,Weng X,Wang Z,Sun D,Yakufu W,Pang Z,Huang Z,Ge J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Aug 01 00:00:00 EDT 2021

Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.

Nature communications

Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jun 08 00:00:00 EDT 2021

Mechanical Stress Induce PG-E2 in Murine Synovial Fibroblasts Originating from the Temporomandibular Joint.

Cells

Nazet U,Feulner L,Muschter D,Neubert P,Schatz V,Grässel S,Jantsch J,Proff P,Schröder A,Kirschneck C

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2021

Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice.

Frontiers in pharmacology

Han H,Peng G,Meister M,Yao H,Yang JJ,Zou MH,Liu ZR,Ji X

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat Apr 02 00:00:00 EDT 2022

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.

Cellular and molecular gastroenterology and hepatology

Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jan 24 00:00:00 EST 2022

Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice.

Physiological reports

Miura I,Komine S,Okada K,Wada S,Warabi E,Uchida F,Oh S,Suzuki H,Mizokami Y,Shoda J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat May 01 00:00:00 EDT 2021

Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).

PloS one

Lin CK,Huang TH,Yang CT,Shi CS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Oct 12 00:00:00 EDT 2021

Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).

PloS one

Lin CK,Huang TH,Yang CT,Shi CS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Oct 12 00:00:00 EDT 2021

Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.

Nature communications

Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon May 17 00:00:00 EDT 2021

Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.

Nature communications

Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon May 17 00:00:00 EDT 2021

Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis.

Frontiers in immunology

Alam J,de Paiva CS,Pflugfelder SC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Dec 10 00:00:00 EST 2021

Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.

Cell reports

Dang MT,Gonzalez MV,Gaonkar KS,Rathi KS,Young P,Arif S,Zhai L,Alam Z,Devalaraja S,To TKJ,Folkert IW,Raman P,Rokita JL,Martinez D,Taroni JN,Shapiro JA,Greene CS,Savonen C,Mafra F,Hakonarson H,Curran T,Haldar M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Mar 30 00:00:00 EDT 2021

Inflammation-induced alterations in maternal-fetal Heme Oxygenase (HO) are associated with sustained innate immune cell dysregulation in mouse offspring.

PloS one

Ozen M,Zhao H,Kalish F,Yang Y,Jantzie LL,Wong RJ,Stevenson DK

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Nov 17 00:00:00 EST 2021

A Population of M2 Macrophages Associated With Bone Formation.

Frontiers in immunology

Olmsted-Davis E,Mejia J,Salisbury E,Gugala Z,Davis AR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Dec 13 00:00:00 EST 2021

Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance.

Cellular and molecular gastroenterology and hepatology

Zhang X,Liu X,Zhou W,Du Q,Yang M,Ding Y,Hu R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunocytochemistry

Fri Mar 25 00:00:00 EDT 2022

TcpC inhibits neutrophil extracellular trap formation by enhancing ubiquitination mediated degradation of peptidylarginine deiminase 4.

Nature communications

Ou Q,Fang JQ,Zhang ZS,Chi Z,Fang J,Xu DY,Lu KZ,Qian MQ,Zhang DY,Guo JP,Gao W,Zhang NR,Pan JP

11-0112-41 was used in Flow Cytometry to investigate the influence of TcpC on neutrophil extracellular trap formation and related mechanisms.

Wed Jun 09 00:00:00 EDT 2021

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade.

JCI insight

Ferrere G,Tidjani Alou M,Liu P,Goubet AG,Fidelle M,Kepp O,Durand S,Iebba V,Fluckiger A,Daillère R,Thelemaque C,Grajeda-Iglesias C,Alves Costa Silva C,Aprahamian F,Lefevre D,Zhao L,Ryffel B,Colomba E,Arnedos M,Drubay D,Rauber C,Raoult D,Asnicar F,Spector T,Segata N,Derosa L,Kroemer G,Zitvogel L

11-0112-41 was used in Flow Cytometry to se preclinical tumor models to address the functional impact of a ketogenic diet on the host immune system and tumor immunosurveillance.

Mon Jan 25 00:00:00 EST 2021

M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors.

Journal of nanobiotechnology

Wang Y,Gong X,Li J,Wang H,Xu X,Wu Y,Wang J,Wang S,Li Y,Zhang Z

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Neutralization

Sat Nov 27 00:00:00 EST 2021

Abraxane-induced bone marrow CD11b⁺ myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with ⁶⁴Cu-labeled anti-CD11b and prevented by anti-CSF-1.

Theranostics

Cao Q,Huang Q,Wang YA,Li C

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jul 23 00:00:00 EDT 2021

Loss of circadian protection against influenza infection in adult mice exposed to hyperoxia as neonates.

eLife

Issah Y,Naik A,Tang SY,Forrest K,Brooks TG,Lahens N,Theken KN,Mermigos M,Sehgal A,Worthen GS,FitzGerald GA,Sengupta S

11-0112-41 was used in Flow Cytometry to show that neonatal hyperoxia abolishes the clock-mediated time of day protection from influenza A virus in mice, independent of viral burden through host tolerance pathways.

Tue Mar 02 00:00:00 EST 2021

Mechanism of exosomal miR-155 derived from bone marrow mesenchymal stem cells on stemness maintenance and drug resistance in myeloma cells.

Journal of orthopaedic surgery and research

Gao X,Zhou J,Wang J,Dong X,Chang Y,Jin Y

11-0112-41 was used in Flow Cytometry to explore the effect of exosomal miR-155 derived from bone marrow mesenchymal stem cells (BMSCs) on stemness maintenance and drug resistance in MPC-11 multiple myeloma cells.

Sun Oct 24 00:00:00 EDT 2021

Increased Levels of IL-16 in the Central Nervous System during Neuroinflammation Are Associated with Infiltrating Immune Cells and Resident Glial Cells.

Biology

Hridi SU,Barbour M,Wilson C,Franssen AJ,Harte T,Bushell TJ,Jiang HR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry (Frozen)

Thu May 27 00:00:00 EDT 2021

Quantification of zinc intoxication of Candida glabrata after phagocytosis by primary macrophages.

STAR protocols

Penninger P,Riedelberger M,Tsymala I,Arzani H,Jenull S,Kuchler K

11-0112-41 was used in Flow Cytometry to quantify Zn2+-mediated clearance of the human fungal pathogen C. glabrata after phagocytosis by innate immune cells.

Fri Mar 19 00:00:00 EDT 2021

Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis.

Cell reports

Nanou A,Bourbouli M,Vetrano S,Schaeper U,Ley S,Kollias G

11-0112-41 was used in Flow Cytometry to investigate in vivo the role of Tumor progression locus 2 (Tpl2), a mitogen-activated protein kinase kinase kinase (MAP3K) member with pleiotropic effects in inflammation and cancer.

Tue May 25 00:00:00 EDT 2021

Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1^G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner.

Journal of neuroinflammation

MacLean M,Juranek J,Cuddapah S,López-Díez R,Ruiz HH,Hu J,Frye L,Li H,Gugger PF,Schmidt AM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry (PFA fixed)

Tue Jun 15 00:00:00 EDT 2021

Dual Activity of Ginsenoside Rb1 in Hypertrophic Cardiomyocytes and Activated Macrophages: Implications for the Therapeutic Intervention of Cardiac Hypertrophy.

Journal of inflammation research

Wang S,Cui Y,Xiong M,Li M,Wang P,Cui J,Du X,Chen Y,Zhang T

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Sat Apr 23 00:00:00 EDT 2022

Circular RNA SMEK1 promotes neuropathic pain in rats through targeting microRNA-216a-5p to mediate Thioredoxin Interacting Protein (TXNIP) expression.

Bioengineered

Xin Y,Song X,Ge Q

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Western Blot

Wed Dec 01 00:00:00 EST 2021

E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.

Nature communications

Gao P,Ma X,Yuan M,Yi Y,Liu G,Wen M,Jiang W,Ji R,Zhu L,Tang Z,Yu Q,Xu J,Yang R,Xia S,Yang M,Pan J,Yuan H,An H

11-0112 was used in Flow cytometry/Cell sorting to show that E3 ligase Nedd4l positively regulates antiviral immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.

Fri Feb 19 00:00:00 EST 2021

Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.

Journal of neuroinflammation

Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Feb 18 00:00:00 EST 2021

Mycobacterium tuberculosis Load in Host Cells and the Antibacterial Activity of Alveolar Macrophages Are Linked and Differentially Regulated in Various Lung Lesions of Patients with Pulmonary Tuberculosis.

International journal of molecular sciences

Ufimtseva EG,Eremeeva NI,Umpeleva TV,Vakhrusheva DV,Skornyakov SN

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Fri Mar 26 00:00:00 EDT 2021

Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis.

Frontiers in cardiovascular medicine

Ju B,Guo O,Benissan-Messan DZ,Shawver MH,Chen P,Geng B,Wei S,Yaron JR,Lucas AR,Zhu H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry (PFA fixed)

Fri May 20 00:00:00 EDT 2022

Serp-1 Promotes Corneal Wound Healing by Facilitating Re-epithelialization and Inhibiting Fibrosis and Angiogenesis.

Frontiers in cardiovascular medicine

Ju B,Guo O,Benissan-Messan DZ,Shawver MH,Chen P,Geng B,Wei S,Yaron JR,Lucas AR,Zhu H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry (PFA fixed)

Fri May 20 00:00:00 EDT 2022

Developmental chronodisruption alters placental signaling in mice.

PloS one

Clarkson-Townsend DA,Bales KL,Hermetz KE,Burt AA,Pardue MT,Marsit CJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunocytochemistry

Wed Nov 24 00:00:00 EST 2021

TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation.

Nature communications

Iizasa E,Chuma Y,Uematsu T,Kubota M,Kawaguchi H,Umemura M,Toyonaga K,Kiyohara H,Yano I,Colonna M,Sugita M,Matsuzaki G,Yamasaki S,Yoshida H,Hara H

11-0112-41 was used in Flow Cytometry to show that the DAP12-associated triggering receptor expressed on myeloid cells 2 (TREM2) recognizes mycobacterial cell-wall mycolic acid (MA)-containing lipids and suggest a mechanism by which mycobacteria control host immunity via TREM2.

Fri Apr 16 00:00:00 EDT 2021

Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Sang W,Xie L,Wang G,Li J,Zhang Z,Li B,Guo S,Deng CX,Dai Y

11-0112 was used in Flow cytometry/Cell sorting to presents a multifunctional metal-phenolic nanoplatform for efficient X-ray mediated RT-RDT in combination with immunotherapy and may provide a new therapeutic option for cancer treatment.

Mon Feb 01 00:00:00 EST 2021

Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution.

Nature communications

Lima LG,Ham S,Shin H,Chai EPZ,Lek ESH,Lobb RJ,Müller AF,Mathivanan S,Yeo B,Choi Y,Parker BS,Möller A

11-0112-41 was used in Flow Cytometry to show that microenvironmental cytokines, particularly CCL2, decorate cancer exosomes via binding to surface glycosaminoglycan side chains of proteoglycans, causing exosome accumulation in specific cell subsets and organs.

Thu Jun 10 00:00:00 EDT 2021

Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution.

Nature communications

Lima LG,Ham S,Shin H,Chai EPZ,Lek ESH,Lobb RJ,Müller AF,Mathivanan S,Yeo B,Choi Y,Parker BS,Möller A

Thu Jun 10 00:00:00 EDT 2021

Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution.

Nature communications

Lima LG,Ham S,Shin H,Chai EPZ,Lek ESH,Lobb RJ,Müller AF,Mathivanan S,Yeo B,Choi Y,Parker BS,Möller A

Thu Jun 10 00:00:00 EDT 2021

Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution.

Nature communications

Lima LG,Ham S,Shin H,Chai EPZ,Lek ESH,Lobb RJ,Müller AF,Mathivanan S,Yeo B,Choi Y,Parker BS,Möller A

Thu Jun 10 00:00:00 EDT 2021

Systemic administration of β-glucan induces immune training in microglia.

Journal of neuroinflammation

Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Feb 22 00:00:00 EST 2021

Myocardial infarction accelerates breast cancer via innate immune reprogramming.

Nature medicine

Koelwyn GJ,Newman AAC,Afonso MS,van Solingen C,Corr EM,Brown EJ,Albers KB,Yamaguchi N,Narke D,Schlegel M,Sharma M,Shanley LC,Barrett TJ,Rahman K,Mezzano V,Fisher EA,Park DS,Newman JD,Quail DF,Nelson ER,Caan BJ,Jones LW,Moore KJ

11-0112 was used in Flow cytometry/Cell sorting to show that myocardial infarction (MI) accelerates breast cancer outgrowth and cancer-specific mortality in mice and humans. I.

Tue Sep 01 00:00:00 EDT 2020

MAFG-driven astrocytes promote CNS inflammation.

Nature

Wheeler MA,Clark IC,Tjon EC,Li Z,Zandee SEJ,Couturier CP,Watson BR,Scalisi G,Alkwai S,Rothhammer V,Rotem A,Heyman JA,Thaploo S,Sanmarco LM,Ragoussis J,Weitz DA,Petrecca K,Moffitt JR,Becher B,Antel JP,Prat A,Quintana FJ

11-0112-41 was used in Flow Cytometry to identify candidate therapeutic targets in multiple sclerosis.

Sat Feb 01 00:00:00 EST 2020

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells.

Nature

Zhang B,Ma S,Rachmin I,He M,Baral P,Choi S,Gonçalves WA,Shwartz Y,Fast EM,Su Y,Zon LI,Regev A,Buenrostro JD,Cunha TM,Chiu IM,Fisher DE,Hsu YC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Wed Jan 01 00:00:00 EST 2020

Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP.

Immunity

Zhou Y,Fei M,Zhang G,Liang WC,Lin W,Wu Y,Piskol R,Ridgway J,McNamara E,Huang H,Zhang J,Oh J,Patel JM,Jakubiak D,Lau J,Blackwood B,Bravo DD,Shi Y,Wang J,Hu HM,Lee WP,Jesudason R,Sangaraju D,Modrusan Z,Anderson KR,Warming S,Roose-Girma M,Yan M

11-0112-41 was used in Flow Cytometry to examine the effect of blocking apoptotic cell clearance on anti-tumor immune response.

Tue Feb 18 00:00:00 EST 2020

Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.

Cancer cell

Marjanovic ND,Hofree M,Chan JE,Canner D,Wu K,Trakala M,Hartmann GG,Smith OC,Kim JY,Evans KV,Hudson A,Ashenberg O,Porter CBM,Bejnood A,Subramanian A,Pitter K,Yan Y,Delorey T,Phillips DR,Shah N,Chaudhary O,Tsankov A,Hollmann T,Rekhtman N,Massion PP,Poirier JT,Mazutis L,Li R,Lee JH,Amon A,Rudin CM,Jacks T,Regev A,Tammela T

11-0112-41 was used in Flow Cytometry to profile cellular transcriptomes of lung tumours at different stages.

Mon Aug 10 00:00:00 EDT 2020

Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.

Nano-micro letters

Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat Nov 21 00:00:00 EST 2020

The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens.

The Journal of experimental medicine

Kang L,Zhang X,Ji L,Kou T,Smith SM,Zhao B,Guo X,Pineda-Torra I,Wu L,Hu X

11-0112-41 was used in Flow Cytometry to demonstrate that colonic macrophage-intrinsic RBP-J dynamically orchestrates intestinal immunity against pathogen infections by interfacing with key immune cells of T and innate lymphoid cell lineages.

Mon Apr 06 00:00:00 EDT 2020

LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes.

The EMBO journal

Liu Z,Xu E,Zhao HT,Cole T,West AB

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunocytochemistry

Thu Oct 15 00:00:00 EDT 2020

IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.

Arteriosclerosis, thrombosis, and vascular biology

Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2020

Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.

PLoS biology

Li J,Zhao Y,Choi J,Ting KK,Coleman P,Chen J,Cogger VC,Wan L,Shi Z,Moller T,Zheng X,Vadas MA,Gamble JR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Mon Jun 01 00:00:00 EDT 2020

Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.

British journal of pharmacology

De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat Feb 01 00:00:00 EST 2020

Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.

Mucosal immunology

Wang C,Li Q,Lv J,Sun X,Cao Y,Yu K,Miao C,Zhang ZS,Yao Z,Wang Q

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.

Glia

Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2020

Deficiency in ZMPSTE24 and resulting farnesyl-prelamin A accumulation only modestly affect mouse adipose tissue stores.

Journal of lipid research

Heizer PJ,Yang Y,Tu Y,Kim PH,Chen NY,Hu Y,Yoshinaga Y,de Jong PJ,Vergnes L,Morales JE,Li RL,Jackson N,Reue K,Young SG,Fong LG

11-0112 was used in Flow cytometry/Cell sorting to generate a conditional knockout Zmpste24 allele and use it to create adipocyte-specific Zmpste24-knockout mice.

Sun Mar 01 00:00:00 EST 2020

Inhibition of IDO leads to IL-6-dependent systemic inflammation in mice when combined with photodynamic therapy.

Cancer immunology, immunotherapy : CII

Wachowska M,Stachura J,Tonecka K,Fidyt K,Braniewska A,Sas Z,Kotula I,Rygiel TP,Boon L,Golab J,Muchowicz A

11-0112-41 was used in Flow Cytometry to investigate the antitumor potential of photodynamic therapy combined with indoleamine 2,3-dioxygenase 1 inhibitor in the murine 4T1 and E0771 orthotopic breast cancer models.

Mon Jun 01 00:00:00 EDT 2020

Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging.

The journals of gerontology. Series A, Biological sciences and medical sciences

Mau T,O'Brien M,Ghosh AK,Miller RA,Yung R

11-0112 was used in Flow cytometry/Cell sorting to study the effects of three drugs identified in the Interventions Testing Program on inflammation in gonadal white adipose tissue of HET3 mice.

Wed Jan 01 00:00:00 EST 2020

Characterization and regulation of osteoclast precursors following chronic Porphyromonas gingivalis infection.

Journal of leukocyte biology

Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Oct 01 00:00:00 EDT 2020

IL-1-dependent electrophysiological changes and cardiac neural remodeling in a mouse model of Kawasaki disease vasculitis.

Clinical and experimental immunology

Abe M,Rastelli DD,Gomez AC,Cingolani E,Lee Y,Soni PR,Fishbein MC,Lehman TJA,Shimada K,Crother TR,Chen S,Noval Rivas M,Arditi M

11-0112 was used in Immunohistochemistry to show that these ECG changes are recapitulated in the Lactobacillus casei cell wall extract (LCWE)-induced KD vasculitis mouse model.

Sun Mar 01 00:00:00 EST 2020

Mouse bone marrow mesenchymal stem cells with distinct p53 statuses display differential characteristics.

Molecular medicine reports

Wang B,Wang L,Mao J,Wen H,Xu L,Ren Y,Du H,Yang H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri May 01 00:00:00 EDT 2020

Pharmacological modulation and genetic deletion of REV-ERBα and REV-ERBβ regulates dendritic cell development.

Biochemical and biophysical research communications

Amir M,Campbell S,Kamenecka TM,Solt LA

11-0112-41 was used in Flow Cytometry to define the role of the nuclear receptors REV-ERBα and REV-ERBβ in dendritic cells.

Sun Jul 05 00:00:00 EDT 2020

Senolytic Agent Navitoclax Inhibits Angiotensin II-Induced Heart Failure in Mice.

Journal of cardiovascular pharmacology

Jia K,Dai Y,Liu A,Li X,Wu L,Lu L,Bao Y,Jin Q

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Thu Oct 01 00:00:00 EDT 2020

Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.

BioMed research international

Jiang JK,Hong LJ,Lu YQ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Dec 16 00:00:00 EST 2020

Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.

BioMed research international

Jiang JK,Hong LJ,Lu YQ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Dec 16 00:00:00 EST 2020

Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche.

Integrative biology : quantitative biosciences from nano to macro

Gilchrist AE,Harley BAC

11-0112-41 was used in Flow Cytometry to investigate the mechanism of how marrow-derived mesenchymal stromal and progenitor cells impacts hematopoietic stem cells fate decisions.

Fri Jul 10 00:00:00 EDT 2020

Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells.

Cell death & disease

Zheng Z,Jia S,Shao C,Shi Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu May 07 00:00:00 EDT 2020

Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells.

Cell death & disease

Zheng Z,Jia S,Shao C,Shi Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu May 07 00:00:00 EDT 2020

Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure.

Frontiers in immunology

Hsu CY,Lin YC,Chang LY,Huang SK,Huang CH,Yang CK,Huang CT,Lin CY

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jun 15 00:00:00 EDT 2021

Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.

Journal of clinical & cellular immunology

Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat Aug 13 00:00:00 EDT 2022

The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.

Nature communications

Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2020

The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.

Nature communications

Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2020

Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.

Cancers

Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Nov 20 00:00:00 EST 2020

Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.

Cancers

Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Nov 20 00:00:00 EST 2020

Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization.

Frontiers in immunology

Chandran S,Schilke RM,Blackburn CMR,Yurochko A,Mirza R,Scott RS,Finck BN,Woolard MD

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Mar 29 00:00:00 EDT 2021

Ly6c^Lo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.

Scientific reports

Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Apr 28 00:00:00 EDT 2020

Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.

Cancers

Kuziel G,Thompson V,D'Amato JV,Arendt LM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jul 28 00:00:00 EDT 2020

The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells.

Scientific reports

Rai V,Wood MB,Feng H,Schabla NM,Tu S,Zuo J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Sep 16 00:00:00 EDT 2020

The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells.

Scientific reports

Rai V,Wood MB,Feng H,Schabla NM,Tu S,Zuo J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Sep 16 00:00:00 EDT 2020

Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.

ImmunoHorizons

Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Oct 19 00:00:00 EDT 2020

TNFAIP3 Plays a Role in Aging of the Hematopoietic System.

Frontiers in immunology

Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Apr 28 00:00:00 EDT 2021

Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.

eLife

Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

CD103⁺ cDC1 and endogenous CD8⁺ T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.

Nature communications

Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Dec 02 00:00:00 EST 2020

Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System.

Biomedicines

Hong Y,Singh N,Bamopoulos S,Gjerga E,Schmalbrock LK,Balabanian K,Schick M,Keller U,Wirth M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Dec 09 00:00:00 EST 2020

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.

Cell death & disease

Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Nov 30 00:00:00 EST 2020

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.

Cell death & disease

Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Nov 30 00:00:00 EST 2020

L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men.

Cells

Drescher HK,Schippers A,Rosenhain S,Gremse F,Bongiovanni L,Bruin A,Eswaran S,Gallage SU,Pfister D,Szydlowska M,Heikenwalder M,Weiskirchen S,Wagner N,Trautwein C,Weiskirchen R,Kroy DC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Apr 29 00:00:00 EDT 2020

Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.

JCI insight

Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Aug 20 00:00:00 EDT 2020

Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.

Frontiers in immunology

Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Apr 12 00:00:00 EDT 2021

Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.

Nature communications

Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Aug 27 00:00:00 EDT 2020

Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.

JCI insight

Hadas R,Gershon E,Cohen A,Atrakchi O,Lazar S,Golani O,Dassa B,Elbaz M,Cohen G,Eilam R,Dekel N,Neeman M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2020

Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b⁺Ly6G^- myeloid cells.

Aging

Fang Y,Gu Y,Li L,Zhu L,Qian J,Zhao C,Xu L,Wei W,Du Y,Yuan N,Zhang S,Yuan Y,Xu Y,Jiang C,Wang J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Nov 24 00:00:00 EST 2020

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.

Cells

Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jul 07 00:00:00 EDT 2020

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.

Stem cell research & therapy

Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Nov 27 00:00:00 EST 2020

Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.

Stem cell research & therapy

Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Nov 27 00:00:00 EST 2020

Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.

Cell reports

Cham LB,Torrez Dulgeroff LB,Tal MC,Adomati T,Li F,Bhat H,Huang A,Lang PA,Moreno ME,Rivera JM,Galkina SA,Kosikova G,Stoddart CA,McCune JM,Myers LM,Weissman IL,Lang KS,Hasenkrug KJ

11-0112 was used in Flow cytometry/Cell sorting to indicate that CD47 blockade not only enhances the function of innate immune cells but also links to adaptive immune responses through improved APC function.

Tue Apr 14 00:00:00 EDT 2020

GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.

Cells

Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jan 03 00:00:00 EST 2020

Differential Activation of Macrophages Based on Their Environment in Advanced Age.

Chonnam medical journal

Lee DY,Lim JS,Cho KA

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2020

Role of IL-4 in bone marrow driven dysregulated angiogenesis and age-related macular degeneration.

eLife

Baba T,Miyazaki D,Inata K,Uotani R,Miyake H,Sasaki SI,Shimizu Y,Inoue Y,Nakamura K

11-0112 was used in Immunohistochemistry to determine the functional role of IL-4 in CNV formation using murine choroidal neovascularization model.

Tue May 05 00:00:00 EDT 2020

Macrophage NCOR1 Deficiency Ameliorates Myocardial Infarction and Neointimal Hyperplasia in Mice.

Journal of the American Heart Association

Du LJ,Sun JY,Zhang WC,Wang YL,Zhu H,Liu T,Gao MZ,Zheng C,Zhang YY,Liu Y,Liu Y,Shao S,Zhang XQ,Leng Q,Auwerx J,Duan SZ

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that NCOR1 is a critical regulator of macrophage inflammation and proliferation and that deficiency of NCOR1 in macrophages attenuates MI and neointimal hyperplasia.

Tue Aug 04 00:00:00 EDT 2020

Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage.

Nature communications

Chen J,Wang L,Xu H,Xing L,Zhuang Z,Zheng Y,Li X,Wang C,Chen S,Guo Z,Liang Q,Wang Y

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that the meningeal lymphatics drain extravasated erythrocytes from CSF into CLNs after SAH, while suggesting that modulating this draining may offer therapeutic approaches to alleviate SAH severity.

Mon Jun 22 00:00:00 EDT 2020

Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma.

Cancers

Shirley SA,Lundberg CG,Heller R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Wed Oct 21 00:00:00 EDT 2020

PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitis.

Theranostics

Jin K,Liu Y,Shi Y,Zhang H,Sun Y,Zhangyuan G,Wang F,Yu W,Wang J,Tao X,Chen X,Zhang W,Sun B

11-0112 was used in Flow cytometry/Cell sorting to indicate that PTPROt plays a dual role in inflammation via the NF-κB signaling pathway in liver macrophages during NASH.

Mon Jul 26 00:00:00 EDT 2021

Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues.

Cells

Iannotta L,Biosa A,Kluss JH,Tombesi G,Kaganovich A,Cogo S,Plotegher N,Civiero L,Lobbestael E,Baekelandt V,Cookson MR,Greggio E

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry (PFA fixed)

Thu Oct 22 00:00:00 EDT 2020

Chimeric apoptotic bodies functionalized with natural membrane and modular delivery system for inflammation modulation.

Science advances

Dou G,Tian R,Liu X,Yuan P,Ye Q,Liu J,Liu S,Zhou J,Deng Z,Chen X,Liu S,Jin Y

11-0112 was used in Flow cytometry/Cell sorting to provides strategies to arbitrarily engineer modular EVs that integrate the advantages of natural EVs and synthetic materials for various applications.

Wed Jul 01 00:00:00 EDT 2020

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.

Cell reports

Hidalgo San Jose L,Sunshine MJ,Dillingham CH,Chua BA,Kruta M,Hong Y,Hatters DM,Signer RAJ

11-0112 was used in Flow cytometry/Cell sorting to show that hematopoietic stem cells (HSCs) are dependent on low protein synthesis to maintain proteostasis, which promotes their self-renewal.

Tue Jan 07 00:00:00 EST 2020

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.

Cell reports

Viaud M,Abdel-Wahab O,Gall J,Ivanov S,Guinamard R,Sore S,Merlin J,Ayrault M,Guilbaud E,Jacquel A,Auberger P,Wang N,Levine RL,Tall AR,Yvan-Charvet L

11-0112 was used in Flow cytometry/Cell sorting to identify somatic mutations in ABCA1 that subvert its anti-proliferative and cholesterol efflux functions and permit the progression of myeloid neoplasms.

Tue Mar 10 00:00:00 EDT 2020

Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.

Frontiers in pharmacology

Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y

11-0112-41 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.

Tue Feb 16 00:00:00 EST 2021

Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.

Frontiers in pharmacology

Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y

11-0112-41 was used in Flow Cytometry to find that FGFR3 had a novel regulatory mechanism for the stemness of LSCs in AML, and provided a promising anti-leukemia approach by interrupting FGFR3.

Tue Feb 16 00:00:00 EST 2021

Neurokinin-1 Receptor Signaling Is Required for Efficient Ca²⁺ Flux in T-Cell-Receptor-Activated T Cells.

Cell reports

Morelli AE,Sumpter TL,Rojas-Canales DM,Bandyopadhyay M,Chen Z,Tkacheva O,Shufesky WJ,Wallace CT,Watkins SC,Berger A,Paige CJ,Falo LD,Larregina AT

11-0112 was used in Flow cytometry/Cell sorting to demonstrate an effect of the NK1R in T cells that is relevant for immunotherapies based on pro-inflammatory neuropeptides and its receptors.

Tue Mar 10 00:00:00 EDT 2020

Glucocorticoids Promote the Onset of Acute Experimental Colitis and Cancer by Upregulating mTOR Signaling in Intestinal Epithelial Cells.

Cancers

Zhang Z,Dong L,Jia A,Chen X,Yang Q,Wang Y,Wang Y,Liu R,Cao Y,He Y,Bi Y,Liu G

11-0112 was used in Flow cytometry/Cell sorting to indicate that glucocorticoid-induced mTOR signaling in epithelial cells is required in the early stages of acute ulcerative colitis by modulating the dynamics of innate immune cell recruitment and activation.

Sat Apr 11 00:00:00 EDT 2020

Diverse CD8 T Cell Responses to Viral Infection Revealed by the Collaborative Cross.

Cell reports

Martin MD,Sompallae R,Winborn CS,Harty JT,Badovinac VP

11-0112 was used in Flow cytometry/Cell sorting to advance the utility of the Collaborative Cross (CC) as a tool to analyze the immune response to viral infection.

Tue Apr 14 00:00:00 EDT 2020

A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling.

Cell reports

Donado CA,Cao AB,Simmons DP,Croker BA,Brennan PJ,Brenner MB

11-0112 was used in Flow cytometry/Cell sorting to describe an alternative, two-cell model for IL-1β release where invariant natural killer T (iNKT) cells use the death receptor pathway to instruct antigen-presenting cells to secrete IL-1β.

Tue Apr 07 00:00:00 EDT 2020

The Innate Immune Response to Infection Induces Erythropoietin-Dependent Replenishment of the Dendritic Cell Compartment.

Frontiers in immunology

Einwächter H,Heiseke A,Schlitzer A,Gasteiger G,Adler H,Voehringer D,Manz MG,Ruzsics Z,Dölken L,Koszinowski UH,Sparwasser T,Reindl W,Jordan S

11-0112-41 was used in Flow Cytometry to investigate the molecular and cellular mechanisms of inflammation-induced dendritic cell generation.

Mon Apr 19 00:00:00 EDT 2021

NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis.

EBioMedicine

Wei M,Ma Y,Shen L,Xu Y,Liu L,Bu X,Guo Z,Qin H,Li Z,Wang Z,Wu K,Yao L,Li J,Zhang J

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that NDRG2 is an essential colonic epithelial barrier regulator and plays an important role in gut homeostasis maintenance and colitis-associated tumour development.

Sun Nov 01 00:00:00 EDT 2020

Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.

Communications biology

Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S

11-0112 was used in Flow cytometry/Cell sorting to show that a specific small-molecule tankyrase inhibitor, G007-LK, decreases WNT/β-catenin and YAP signaling in the syngeneic murine B16-F10 and Clone M-3 melanoma models and sensitizes the tumors to anti-PD-1 immune checkpoint therapy.

Fri Apr 24 00:00:00 EDT 2020

GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation.

Cell reports

Castro-Dopico T,Fleming A,Dennison TW,Ferdinand JR,Harcourt K,Stewart BJ,Cader Z,Tuong ZK,Jing C,Lok LSC,Mathews RJ,Portet A,Kaser A,Clare S,Clatworthy MR

11-0112 was used in Flow cytometry/Cell sorting to identify granulocyte-macrophage colony stimulating factor (GM-CSF) as a critical regulator of intestinal macrophage activation in patients with IBD and mice with dextran sodium sulfate (DSS)-induced colitis.

Tue Jul 07 00:00:00 EDT 2020

Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity.

Cell reports

Han CY,Kang I,Harten IA,Gebe JA,Chan CK,Omer M,Alonge KM,den Hartigh LJ,Gomes Kjerulf D,Goodspeed L,Subramanian S,Wang S,Kim F,Birk DE,Wight TN,Chait A

11-0112-41 was used in Flow Cytometry to provide insights into the role of adipocyte- and macrophage-derived proteoglycans in adipose tissue inflammation in obesity.

Tue Jun 30 00:00:00 EDT 2020

Distinct Waves from the Hemogenic Endothelium Give Rise to Layered Lymphoid Tissue Inducer Cell Ontogeny.

Cell reports

Simic M,Manosalva I,Spinelli L,Gentek R,Shayan RR,Siret C,Girard-Madoux M,Wang S,de Fabritus L,Verschoor J,Kerdiles YM,Bajenoff M,Stumm R,Golub R,van de Pavert SA

11-0112 was used in Flow cytometry/Cell sorting to identify a major contribution from embryonic hemogenic endothelium, but not the yolk sac, toward LTi progenitors.

Tue Aug 11 00:00:00 EDT 2020

Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.

Nature

Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S

11-0112 was used in Flow cytometry/Cell sorting to identify polyvinyl alcohol as a functionally superior replacement for serum albumin that is compatible with good manufacturing practice.

Mon Jul 01 00:00:00 EDT 2019

Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS.

Cell

Chao CC,Gutiérrez-Vázquez C,Rothhammer V,Mayo L,Wheeler MA,Tjon EC,Zandee SEJ,Blain M,de Lima KA,Takenaka MC,Avila-Pacheco J,Hewson P,Liu L,Sanmarco LM,Borucki DM,Lipof GZ,Trauger SA,Clish CB,Antel JP,Prat A,Quintana FJ

11-0112-41 was used in Flow Cytometry to define a novel immunometabolic mechanism that drives pro-inflammatory astrocyte activities.

Thu Dec 12 00:00:00 EST 2019

The cis-Regulatory Atlas of the Mouse Immune System.

Cell

Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C

11-0112-41 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.

Thu Feb 07 00:00:00 EST 2019

A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation.

Immunity

Roy K,Mitchell S,Liu Y,Ohta S,Lin YS,Metzig MO,Nutt SL,Hoffmann A

11-0112-41 was used in Flow Cytometry to provide a mechanistic explanation of how dysregulation of this bi-stable circuit might result in pathologic B cell population phenotypes and thus offer new avenues for diagnostic stratification and treatment.

Tue Mar 19 00:00:00 EDT 2019

Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis.

Cell metabolism

Camell CD,Günther P,Lee A,Goldberg EL,Spadaro O,Youm YH,Bartke A,Hubbard GB,Ikeno Y,Ruddle NH,Schultze J,Dixit VD

11-0112 was used in Flow cytometry/Cell sorting to study the role of ageing within alterations of adipose tissue.

Tue Dec 03 00:00:00 EST 2019

Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice.

Nature immunology

Piliponsky AM,Shubin NJ,Lahiri AK,Truong P,Clauson M,Niino K,Tsuha AL,Nedospasov SA,Karasuyama H,Reber LL,Tsai M,Mukai K,Galli SJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Feb 01 00:00:00 EST 2019

Central nervous system regeneration is driven by microglia necroptosis and repopulation.

Nature neuroscience

Lloyd AF,Davies CL,Holloway RK,Labrak Y,Ireland G,Carradori D,Dillenburg A,Borger E,Soong D,Richardson JC,Kuhlmann T,Williams A,Pollard JW,des Rieux A,Priller J,Miron VE

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jul 01 00:00:00 EDT 2019

Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module.

Nature neuroscience

Munji RN,Soung AL,Weiner GA,Sohet F,Semple BD,Trivedi A,Gimlin K,Kotoda M,Korai M,Aydin S,Batugal A,Cabangcala AC,Schupp PG,Oldham MC,Hashimoto T,Noble-Haeusslein LJ,Daneman R

11-0112 was used in Flow cytometry/Cell sorting to analyse the gene expression of endothelial cells in mice, comparing brain endothelial cells with peripheral endothelial cells.

Fri Nov 01 00:00:00 EDT 2019

TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.

Cell stem cell

Yamashita M,Passegué E

11-0112 was used in Flow cytometry/Cell sorting to reveal several TNF-α-mediated pro-survival mechanisms unique to HSCs, highlight an important role for necroptosis in HSC killing, and establish TNF-α as a major pro-survival and pro-regeneration factor for HSCs.

Thu Sep 05 00:00:00 EDT 2019

Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis.

The Journal of experimental medicine

Li S,Wu Y,Yang D,Wu C,Ma C,Liu X,Moynagh PN,Wang B,Hu G,Yang S

11-0112-41 was used in Flow Cytometry to study how GSDMD deficiency in peripheral myeloid cells impaired the infiltration of immune cells into the CNS, leading to the suppression of neuroinflammation and demyelination.

Mon Nov 04 00:00:00 EST 2019

Ly6G⁺ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model.

Cell death and differentiation

Jeon HY,Ham SW,Kim JK,Jin X,Lee SY,Shin YJ,Choi CY,Sa JK,Kim SH,Chun T,Jin X,Nam DH,Kim H

11-0112-41 was used in Flow Cytometry to demonstrate that radiation-induced senescent glioblastoma cells exhibit a senescence-associated secretory phenotype that functions through NFκB signalling to influence changes in the tumour microenvironment.

Tue Oct 01 00:00:00 EDT 2019

STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion.

Cell death and differentiation

Zhang CX,Ye SB,Ni JJ,Cai TT,Liu YN,Huang DJ,Mai HQ,Chen QY,He J,Zhang XS,Zeng YX,Li J,Cui J

11-0112-41 was used in Flow Cytometry to investigate the role of stimulator of interferon genes (STING) in regulation of myeloid-derived suppressor cell differentiation and antitumor immunity in Epstein-Barr virus-associated nasopharyngeal carcinomas.

Fri Nov 01 00:00:00 EDT 2019

Low-Dose Apatinib Optimizes Tumor Microenvironment and Potentiates Antitumor Effect of PD-1/PD-L1 Blockade in Lung Cancer.

Cancer immunology research

Zhao S,Ren S,Jiang T,Zhu B,Li X,Zhao C,Jia Y,Shi J,Zhang L,Liu X,Qiao M,Chen X,Su C,Yu H,Zhou C,Zhang J,Camidge DR,Hirsch FR

11-0112 was used in Flow cytometry/Cell sorting to analyze the impact of apatinib, a smallmolecule VEGFR2-TKI, on the TME in murine Lewis lung carcinoma (LLC) models at different doses alone and in combination with an anti–PD-L1.

Mon Apr 01 00:00:00 EDT 2019

Ablation of endothelial Pfkfb3 protects mice from acute lung injury in LPS-induced endotoxemia.

Pharmacological research

Wang L,Cao Y,Gorshkov B,Zhou Y,Yang Q,Xu J,Ma Q,Zhang X,Wang J,Mao X,Zeng X,Su Y,Verin AD,Hong M,Liu Z,Huo Y

11-0112 was used in Flow cytometry/Cell sorting to investigate if the expression and activity of PFKFB3 was markedly increased in lipopolysaccharide (LPS)-treated human pulmonary arterial endothelial cells (HPAECs) in vitro and in lung endothelial cells of mice challenged with LPS in vivo.

Thu Aug 01 00:00:00 EDT 2019

Inactivation of endothelial adenosine A_2A receptors protects mice from cerebral ischaemia-induced brain injury.

British journal of pharmacology

Zhou Y,Zeng X,Li G,Yang Q,Xu J,Zhang M,Mao X,Cao Y,Wang L,Xu Y,Wang Y,Zhang Y,Xu Z,Wu C,Chen JF,Hoda MN,Liu Z,Hong M,Huo Y

11-0112 was used in Flow cytometry/Cell sorting to help open new approaches to vascular protection after ischaemic stroke.

Mon Jul 01 00:00:00 EDT 2019

Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages.

British journal of pharmacology

Feng L,Sun Y,Song P,Xu L,Wu X,Wu X,Shen Y,Sun Y,Kong L,Wu X,Xu Q

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

Imiquimod-Induced Psoriasis in Mice Depends on the IL-17 Signaling of Keratinocytes.

The Journal of investigative dermatology

Moos S,Mohebiany AN,Waisman A,Kurschus FC

11-0112 was used in Flow cytometry/Cell sorting to study if keratinocytes are a critical cellular target for IL-17A mediated neutrophil attraction and psoriasis development.

Wed May 01 00:00:00 EDT 2019

Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Rotterman TM,Akhter ET,Lane AR,MacPherson KP,García VV,Tansey MG,Alvarez FJ

11-0112 was used in Flow cytometry/Cell sorting to show that both activation of ventral microglia and a CCR2-dependent mechanism are necessary for removal of VGLUT1 synapses and alterations in Ia-circuit function following nerve injuries.

Wed May 01 00:00:00 EDT 2019

Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.

Journal of cellular physiology

Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed May 01 00:00:00 EDT 2019

Identification of a novel selective and potent inhibitor of glycogen synthase kinase-3.

American journal of physiology. Cell physiology

Noori MS,Bhatt PM,Courreges MC,Ghazanfari D,Cuckler C,Orac CM,McMills MC,Schwartz FL,Deosarkar SP,Bergmeier SC,McCall KD,Goetz DJ

11-0112 was used in Flow cytometry/Cell sorting to reveal a novel organic compound, COB-187, which can selectively and potently inhibit glycogen synthase kinase-3.

Sun Dec 01 00:00:00 EST 2019

Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland.

Investigative ophthalmology & visual science

Lee HK,Kim KW,Ryu JS,Jeong HJ,Lee SM,Kim MK

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that a unilateral cut of the corneal nerve results in activation of immune cells on the ocular surface and dysregulation of lacrimal secretion bilaterally through the bidirectional neuronal signals.

Wed Jan 02 00:00:00 EST 2019

Puerarin alters the function of monocytes/macrophages and exhibits chondroprotection in mice.

Molecular medicine reports

Peng L,Xie Z,Pei J,Wang B,Gao Y,Qu Y

11-0112 was used in Flow cytometry/Cell sorting to show puerarin may be a target in the treatment of osteoarthritis as administration diminished the recruitment of inflammatory monocytes in arthritic tissues.

Mon Apr 01 00:00:00 EDT 2019

Antiallodynic Effects of Cannabinoid Receptor 2 (CB₂R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.

Pain research & management

Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Dec 16 00:00:00 EST 2019

Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.

Anti-cancer drugs

Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Oct 01 00:00:00 EDT 2019

TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.

Cell reports

Zeng J,Wang Y,Luo Z,Chang LC,Yoo JS,Yan H,Choi Y,Xie X,Deverman BE,Gradinaru V,Gupton SL,Zlokovic BV,Zhao Z,Jung JU

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Apr 09 00:00:00 EDT 2019

Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.

Nature communications

Zhang X,Zhang H,Xu C,Li X,Li M,Wu X,Pu W,Zhou B,Wang H,Li D,Ding Q,Ying H,Wang H,Zhang H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Sep 13 00:00:00 EDT 2019

PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells.

Cell reports

Tan DQ,Li Y,Yang C,Li J,Tan SH,Chin DWL,Nakamura-Ishizu A,Yang H,Suda T

11-0112 was used in Flow cytometry/Cell sorting to establish the importance of cell-intrinsic protein arginine methyltransferase 5 activity in hematopoietic stem cells.

Tue Feb 26 00:00:00 EST 2019

The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells.

Cell reports

Araujo LP,Maricato JT,Guereschi MG,Takenaka MC,Nascimento VM,de Melo FM,Quintana FJ,Brum PC,Basso AS

11-0112-41 was used in Flow Cytometry to uncover a suppressive role for the SNS in CNS autoimmunity while they identify potential targets for therapeutic intervention.

Tue Sep 17 00:00:00 EDT 2019

Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine.

Scientific reports

Kimura H,Imura YK,Tomiyasu H,Mihara T,Kaji N,Ohno K,Unno T,Tanahashi Y,Jan TR,Tsubone H,Ozaki H,Hori M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Apr 10 00:00:00 EDT 2019

Phc2 controls hematopoietic stem and progenitor cell mobilization from bone marrow by repressing Vcam1 expression.

Nature communications

Bae J,Choi SP,Isono K,Lee JY,Park SW,Choi CY,Han J,Kim SH,Lee HH,Park K,Jin HY,Lee SJ,Park CG,Koseki H,Lee YS,Chun T

11-0112-41 was used in Flow cytometry/Cell sorting to determine the role of PHc2 in controlling the mobilisation of hematopoietic stem and progenitor cells.

Fri Aug 02 00:00:00 EDT 2019

MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.

Journal for immunotherapy of cancer

Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Mycobacterium tuberculosis Drives Expansion of Low-Density Neutrophils Equipped With Regulatory Activities.

Frontiers in immunology

La Manna MP,Orlando V,Paraboschi EM,Tamburini B,Di Carlo P,Cascio A,Asselta R,Dieli F,Caccamo N

11-0112-41 was used in Flow cytometry/Cell sorting to analyze total neutrophils and their low-density and normal-density subsets in patients with active tuberculosis disease, in terms of frequency, phenotype, functional features, and gene expression signature.

Thu Nov 05 00:00:00 EST 2020

Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.

Cellular and molecular gastroenterology and hepatology

Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jun 04 00:00:00 EDT 2019

Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.

Frontiers in immunology

Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Oct 14 00:00:00 EDT 2020

Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.

Frontiers in immunology

Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Sep 28 00:00:00 EDT 2020

Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.

Nature metabolism

Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jan 01 00:00:00 EST 2019

Evodiamine Augments NLRP3 Inflammasome Activation and Anti-bacterial Responses Through Inducing α-Tubulin Acetylation.

Frontiers in pharmacology

Li CG,Zeng QZ,Chen MY,Xu LH,Zhang CC,Mai FY,Zeng CY,He XH,Ouyang DY

11-0112 was used in Flow cytometry/Cell sorting to determine the effect of evodiamine on NLRP3 inflammasome activation in macrophages.

Wed Sep 30 00:00:00 EDT 2020

Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.

Nature communications

Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Feb 22 00:00:00 EST 2019

Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.

Nature communications

Zhu H,Bhatt B,Sivaprakasam S,Cai Y,Liu S,Kodeboyina SK,Patel N,Savage NM,Sharma A,Kaufman RJ,Li H,Singh N

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Mar 06 00:00:00 EST 2019

The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.

Scientific reports

Tellez Freitas CM,Burrell HR,Valdoz JC,Hamblin GJ,Raymond CM,Cox TD,Johnson DK,Andersen JL,Weber KS,Bridgewater LC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jan 30 00:00:00 EST 2019

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.

Nature communications

Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Feb 12 00:00:00 EST 2019

Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.

Cellular and molecular gastroenterology and hepatology

Kiyohara H,Sujino T,Teratani T,Miyamoto K,Arai MM,Nomura E,Harada Y,Aoki R,Koda Y,Mikami Y,Mizuno S,Naganuma M,Hisamatsu T,Kanai T

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Apr 29 00:00:00 EDT 2019

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.

Cell reports

Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunoprecipitation

Tue Jun 04 00:00:00 EDT 2019

Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.

Nature communications

Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Nov 28 00:00:00 EST 2019

Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.

Nature

Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Sun Apr 01 00:00:00 EDT 2018

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Nature

Morioka S,Perry JSA,Raymond MH,Medina CB,Zhu Y,Zhao L,Serbulea V,Onengut-Gumuscu S,Leitinger N,Kucenas S,Rathmell JC,Makowski L,Ravichandran KS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Nov 01 00:00:00 EDT 2018

Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.

Nature

Meisel M,Hinterleitner R,Pacis A,Chen L,Earley ZM,Mayassi T,Pierre JF,Ernest JD,Galipeau HJ,Thuille N,Bouziat R,Buscarlet M,Ringus DL,Wang Y,Li Y,Dinh V,Kim SM,McDonald BD,Zurenski MA,Musch MW,Furtado GC,Lira SA,Baier G,Chang EB,Eren AM,Weber CR,Busque L,Godley LA,Verdú EF,Barreiro LB,Jabri B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue May 01 00:00:00 EDT 2018

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.

Cell

Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Jan 25 00:00:00 EST 2018

Circuit Design Features of a Stable Two-Cell System.

Cell

Zhou X,Franklin RA,Adler M,Jacox JB,Bailis W,Shyer JA,Flavell RA,Mayo A,Alon U,Medzhitov R

11-0112 was used in Flow cytometry/Cell sorting to illustrate principles of cell circuit design and provide a quantitative perspective on cell interactions.

Thu Feb 08 00:00:00 EST 2018

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Cell

Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Jun 28 00:00:00 EDT 2018

Chanzyme TRPM7 Mediates the Ca²⁺ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.

Immunity

Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jan 16 00:00:00 EST 2018

Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A.

Immunity

Wang M,Zhang S,Zheng G,Huang J,Songyang Z,Zhao X,Lin X

11-0112 was used in Flow cytometry/Cell sorting to show CARMA2 serves as a key mediator of IL-17A signaling and its constitutive activation in keratinocytes leads to the onset of psoriasis.

Tue Jul 17 00:00:00 EDT 2018

Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells.

Immunity

Hu G,Cui K,Fang D,Hirose S,Wang X,Wangsa D,Jin W,Ried T,Liu P,Zhu J,Rothenberg EV,Zhao K

11-0112 was used in Flow cytometry/Cell sorting to find that abrupt genome-wide changes at all three levels of chromatin organization occur during the transition from double-negative stage 2 (DN2) to DN3, accompanying the T lineage commitment.

Tue Feb 20 00:00:00 EST 2018

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.

Immunity

Deng M,Tang Y,Li W,Wang X,Zhang R,Zhang X,Zhao X,Liu J,Tang C,Liu Z,Huang Y,Peng H,Xiao L,Tang D,Scott MJ,Wang Q,Liu J,Xiao X,Watkins S,Li J,Yang H,Wang H,Chen F,Tracey KJ,Billiar TR,Lu B

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that hepatocyte released HMGB1 mediates caspase-11- dependent pyroptosis and lethality in sepsis.

Tue Oct 16 00:00:00 EDT 2018

E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.

Immunity

Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Feb 20 00:00:00 EST 2018

E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.

Immunity

Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Feb 20 00:00:00 EST 2018

A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion.

Immunity

Xia P,Wang S,Ye B,Du Y,Li C,Xiong Z,Qu Y,Fan Z

11-0112 was used in Flow cytometry/Cell sorting to study circular RNA-mediated maintenance of hematopoeitic stem cell homeostasis.

Tue Apr 17 00:00:00 EDT 2018

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.

Immunity

Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jun 19 00:00:00 EDT 2018

CD150^high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine.

Cell stem cell

Hirata Y,Furuhashi K,Ishii H,Li HW,Pinho S,Ding L,Robson SC,Frenette PS,Fujisaki J

11-0112-41 was used in Flow Cytometry to describe a Treg subpopulation that controls hematopoietic stem cell (HSC) quiescence and engraftment.

Thu Mar 01 00:00:00 EST 2018

Insulin resistance causes inflammation in adipose tissue.

The Journal of clinical investigation

Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Apr 02 00:00:00 EDT 2018

Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease.

The Journal of clinical investigation

Tsantikos E,Lau M,Castelino CM,Maxwell MJ,Passey SL,Hansen MJ,McGregor NE,Sims NA,Steinfort DP,Irving LB,Anderson GP,Hibbs ML

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.

Journal of the American Society of Nephrology : JASN

Micanovic R,Khan S,Janosevic D,Lee ME,Hato T,Srour EF,Winfree S,Ghosh J,Tong Y,Rice SE,Dagher PC,Wu XR,El-Achkar TM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Mar 01 00:00:00 EST 2018

11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.

Journal of autoimmunity

Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Aug 01 00:00:00 EDT 2018

MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.

Proceedings of the National Academy of Sciences of the United States of America

Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Tue May 01 00:00:00 EDT 2018

MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.

Proceedings of the National Academy of Sciences of the United States of America

Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Tue May 01 00:00:00 EDT 2018

The Synergy of Aging and LPS Exposure in a Mouse Model of Parkinson's Disease.

Aging and disease

Zhao YF,Zhang JF,Lou ZY,Zu HB,Wang ZG,Zeng WC,Xiao BG

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Mon Oct 01 00:00:00 EDT 2018

De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or Macrophages.

Frontiers in immunology

Stüve P,Minarrieta L,Erdmann H,Arnold-Schrauf C,Swallow M,Guderian M,Krull F,Hölscher A,Ghorbani P,Behrends J,Abraham WR,Hölscher C,Sparwasser TD,Berod L

11-0112-41 was used in Flow Cytometry to reveal that acetyl-CoA carboxylase 1-dependent fatty acid synthesis is a crucial mechanism in T cells, but not dendritic cells or macrophages, to fight against mycobacterial infection.

Wed Apr 10 00:00:00 EDT 2019

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.

Glia

Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors.

PLoS pathogens

Leoni V,Vannini A,Gatta V,Rambaldi J,Sanapo M,Barboni C,Zaghini A,Nanni P,Lollini PL,Casiraghi C,Campadelli-Fiume G

11-0112 was used in Flow cytometry/Cell sorting to analyse the efficacy of a fully-virulent HER2-retargeted oncolytic HSV, demonstrating its ability to elicit a local immune response and systemic therapy vaccine effects.

Wed Aug 01 00:00:00 EDT 2018

Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes.

Journal of cellular physiology

Liron T,Raphael B,Hiram-Bab S,Bab IA,Gabet Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Apr 01 00:00:00 EDT 2018

Isolation and characterization of mesenchymal stem cells and its antitumor application on ovarian cancer cell line.

Artificial cells, nanomedicine, and biotechnology

Mohammadian F,Negahdari B

11-0112-41 was used in Flow Cytometry to study the mechanisms regulating mesenchymal stem cells therapeutic activity and their undifferentiated state maintenance.

Sat Dec 01 00:00:00 EST 2018

Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.

Journal of leukocyte biology

Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Feb 01 00:00:00 EST 2018

Betaine Ameliorates Experimental Autoimmune Encephalomyelitis by Inhibiting Dendritic Cell-Derived IL-6 Production and Th17 Differentiation.

Journal of immunology (Baltimore, Md. : 1950)

Yang C,Lai W,Zhou J,Zheng X,Cai Y,Yang W,Xie S,Gao Y,Du C

11-0112 was used in Flow cytometry/Cell sorting to demonstrate the pivotal roles of betaine in modulating MS pathogenesis and suggested that it may serve as a potential novel drug candidate for the treatment of MS.

Thu Feb 15 00:00:00 EST 2018

The Outcome of the Cryptococcus neoformans-Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.

Journal of immunology (Baltimore, Md. : 1950)

De Leon-Rodriguez CM,Rossi DCP,Fu MS,Dragotakes Q,Coelho C,Guerrero Ros I,Caballero B,Nolan SJ,Casadevall A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Jul 15 00:00:00 EDT 2018

Mesenchymal Stem Cells Recruit CCR2⁺ Monocytes To Suppress Allergic Airway Inflammation.

Journal of immunology (Baltimore, Md. : 1950)

Takeda K,Webb TL,Ning F,Shiraishi Y,Regan DP,Chow L,Smith MJ,Ashino S,Guth AM,Hopkins S,Gelfand EW,Dow S

11-0112 was used in Flow cytometry/Cell sorting to show that mesenchymal stem cell activation by IFN-γ, followed by increased expression of CCL2 and recruitment of monocytes to the lungs, is essential for suppression by mesenchymal stem cells in allergen-induced airway hyperresponsiveness and airway inflammation.

Thu Feb 15 00:00:00 EST 2018

Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.

American journal of physiology. Gastrointestinal and liver physiology

Zimmerman KA,Song CJ,Gonzalez-Mize N,Li Z,Yoder BK

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jun 01 00:00:00 EDT 2018

Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.

Molecular medicine reports

Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

A novel method to isolate mesenchymal stem cells from mouse umbilical cord.

Molecular medicine reports

Zhang B,Zhang J,Shi H,Mao F,Wang J,Yan Y,Zhang X,Qian H,Xu W

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jan 01 00:00:00 EST 2018

High fish oil diet promotes liver inflammation and activates the complement system.

Molecular medicine reports

Jin H,Yan C,Xiao T,Yan N,Xu J,Zhou L,Zhou X,Shao Q,Xia S

11-0112 was used in Flow cytometry/Cell sorting to study the effects of a high fish oil diet in mice, thus revealing induced inflammation and activation of the complement system in the liver.

Tue May 01 00:00:00 EDT 2018

Morphine-potentiated cognitive deficits correlate to suppressed hippocampal iNOS RNA expression and an absent type 1 interferon response in LP-BM5 murine AIDS.

Journal of neuroimmunology

McLane VD,Kumar S,Leeming R,Rau S,Willis CL,Cao L

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Fri Jun 15 00:00:00 EDT 2018

Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow.

Experimental and therapeutic medicine

Wang X,Zhao Z,Zhang H,Hou J,Feng W,Zhang M,Guo J,Xia J,Ge Q,Chen X,Wu X

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat Dec 01 00:00:00 EST 2018

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis.

Nature communications

Clemente C,Rius C,Alonso-Herranz L,Martín-Alonso M,Pollán Á,Camafeita E,Martínez F,Mota RA,Núñez V,Rodríguez C,Seiki M,Martínez-González J,Andrés V,Ricote M,Arroyo AG

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Neutralization

Fri Mar 02 00:00:00 EST 2018

Contribution of CD137L to Sensory Hypersensitivity in a Murine Model of Neuropathic Pain.

eNeuro

Wakley AA,Leeming R,Malon J,Arabatzis TJ,Yuen Koh W,Cao L

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Fri Apr 19 00:00:00 EDT 2019

iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.

JCI insight

Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Feb 08 00:00:00 EST 2018

A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.

Nature communications

Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Apr 18 00:00:00 EDT 2018

Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.

Frontiers in immunology

Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Sep 25 00:00:00 EDT 2019

Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.

Journal of neuroinflammation

Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Sep 21 00:00:00 EDT 2018

Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production both in vitro and in a mouse model of inflammation.

The Journal of biological chemistry

Castelblanco M,Lugrin J,Ehirchiou D,Nasi S,Ishii I,So A,Martinon F,Busso N

11-0112 was used in Flow cytometry/Cell sorting to study the effects of exogenous and endogenous hydorgen sulfide (H2S) on NLRP3 inflammasome activation.

Fri Feb 16 00:00:00 EST 2018

Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis.

Cell death & disease

Lai D,Tang J,Chen L,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Fang X,Shu Q,Fan J

11-0112 was used in Flow cytometry/Cell sorting to describe the function of ILC2 in the regulation of lung inflammation by protecting lung endothelial cell from pyroptosis.

Tue Mar 06 00:00:00 EST 2018

Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.

Oncotarget

Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Apr 24 00:00:00 EDT 2018

BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.

Oncotarget

Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Apr 03 00:00:00 EDT 2018

An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.

Scientific reports

Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Nov 02 00:00:00 EDT 2018

Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model.

JCI insight

Flemming S,Luissint AC,Nusrat A,Parkos CA

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu Oct 18 00:00:00 EDT 2018

Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.

Frontiers in physiology

Lim D,Kim W,Lee C,Bae H,Kim J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Wed Sep 30 00:00:00 EDT 2020

Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.

Frontiers in physiology

Lim D,Kim W,Lee C,Bae H,Kim J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Wed Sep 30 00:00:00 EDT 2020

Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria.

Journal of neuroinflammation

Wilson KD,Ochoa LF,Solomon OD,Pal R,Cardona SM,Carpio VH,Keiser PH,Cardona AE,Vargas G,Stephens R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Mon Jun 04 00:00:00 EDT 2018

CD24-p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages.

Cell discovery

Li D,Hu M,Liu Y,Ye P,Du P,Li CS,Cheng L,Liu P,Jiang J,Su L,Wang S,Zheng P,Liu Y

11-0112-41 was used in Flow cytometry/Cell sorting to show that targeted mutation of Cd24 dramatically increased HCC burden while reducing intrahepatic macrophages and DEN-induced hepatocyte apoptosis.

Thu Oct 01 00:00:00 EDT 2020

RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.

The Journal of biological chemistry

Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jun 15 00:00:00 EDT 2018

JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression.

Nature medicine

Zhao X,Guo Y,Jiang C,Chang Q,Zhang S,Luo T,Zhang B,Jia X,Hung MC,Dong C,Lin X

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.

Nature

Kim S,Kim H,Yim YS,Ha S,Atarashi K,Tan TG,Longman RS,Honda K,Littman DR,Choi GB,Huh JR

11-0112 was used in Flow cytometry/Cell sorting to suggest that defined gut commensal bacteria with a propensity to induce TH17 cells may increase the risk of neurodevelopmental disorders in the offspring of pregnant mothers undergoing immune system activation owing to infections or autoinflammatory syndromes.

Thu Sep 28 00:00:00 EDT 2017

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Nature

Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Apr 06 00:00:00 EDT 2017

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.

Nature

Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu May 18 00:00:00 EDT 2017

A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.

Nature

Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu May 18 00:00:00 EDT 2017

Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.

Nature immunology

Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Feb 01 00:00:00 EST 2017

Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.

Circulation research

Yan X,Zhang H,Fan Q,Hu J,Tao R,Chen Q,Iwakura Y,Shen W,Lu L,Zhang Q,Zhang R

11-0112 was used in Flow cytometry/Cell sorting to determine whether Dectin-2 signalling is involved in the healing process and cardiac remodelling after myocardial infarction and to elucidate the underlying molecular mechanisms.

Fri Mar 31 00:00:00 EDT 2017

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.

The Journal of clinical investigation

Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Mar 01 00:00:00 EST 2017

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling.

The Journal of clinical investigation

Quiros M,Nishio H,Neumann PA,Siuda D,Brazil JC,Azcutia V,Hilgarth R,O'Leary MN,Garcia-Hernandez V,Leoni G,Feng M,Bernal G,Williams H,Dedhia PH,Gerner-Smidt C,Spence J,Parkos CA,Denning TL,Nusrat A

11-0112 was used in Flow cytometry/Cell sorting to investigate the mechanisms involved in crosstalk between immune cells and the epithelium in mucosal barrier repair.

Fri Sep 01 00:00:00 EDT 2017

DC subset-specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo.

The Journal of experimental medicine

Lehmann CHK,Baranska A,Heidkamp GF,Heger L,Neubert K,Lühr JJ,Hoffmann A,Reimer KC,Brückner C,Beck S,Seeling M,Kießling M,Soulat D,Krug AB,Ravetch JV,Leusen JHW,Nimmerjahn F,Dudziak D

11-0112 was used in Flow cytometry/Cell sorting to suggest that targeting antigens to FcγRs on DCs may be a promising approach to raise immunogenic or tolerogenic T cell responses to antigens of choice.

Mon May 01 00:00:00 EDT 2017

Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.

The EMBO journal

Kawasaki T,Ito K,Miyata H,Akira S,Kawai T

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jun 14 00:00:00 EDT 2017

Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis.

Autophagy

Qiang L,Sample A,Shea CR,Soltani K,Macleod KF,He YY

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Fri Jul 05 00:00:00 EDT 2019

Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.

Proceedings of the National Academy of Sciences of the United States of America

Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue May 16 00:00:00 EDT 2017

IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.

PLoS medicine

Xu J,Guardado J,Hoffman R,Xu H,Namas R,Vodovotz Y,Xu L,Ramadan M,Brown J,Turnquist HR,Billiar TR

11-0112 was used in Flow cytometry/Cell sorting to suggest that IL33 may initiate early detrimental type 2 immune responses after trauma through ILC2 regulation of neutrophil IL5 production.

Sat Jul 01 00:00:00 EDT 2017

CCR2^- and CCR2⁺ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.

Mucosal immunology

Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Sep 01 00:00:00 EDT 2017

Depletion of microglia exacerbates postischemic inflammation and brain injury.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Wang W,Wang H,Zhou X,Li X,Sun W,Dellinger M,Boyce BF,Xing L

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Lung Epithelial Cell-Derived Microvesicles Regulate Macrophage Migration via MicroRNA-17/221-Induced Integrin β₁ Recycling.

Journal of immunology (Baltimore, Md. : 1950)

Lee H,Zhang D,Wu J,Otterbein LE,Jin Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Aug 15 00:00:00 EDT 2017

Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis.

Journal of immunology (Baltimore, Md. : 1950)

Jie Z,Liang Y,Yi P,Tang H,Soong L,Cong Y,Zhang K,Sun J

11-0112 was used in Flow cytometry/Cell sorting to determine the role of retinoic acid in IL-22 production during hepatitis infection.

Mon May 01 00:00:00 EDT 2017

The Upregulation of Integrin α_Dβ₂ (CD11d/CD18) on Inflammatory Macrophages Promotes Macrophage Retention in Vascular Lesions and Development of Atherosclerosis.

Journal of immunology (Baltimore, Md. : 1950)

Aziz MH,Cui K,Das M,Brown KE,Ardell CL,Febbraio M,Pluskota E,Han J,Wu H,Ballantyne CM,Smith JD,Cathcart MK,Yakubenko VP

11-0112 was used in Flow cytometry/Cell sorting to study the mechanism by which inflammation mediated CD11d upregulation contributes to macrophage retention at inflammatory sites during atherogenesis.

Thu Jun 15 00:00:00 EDT 2017

Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.

International journal of molecular medicine

Zhang B,Wang B,Cao S,Wang Y,Wu D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Impaired phagocytosis of apoptotic cells causes accumulation of bone marrow-derived macrophages in aged mice.

BMB reports

Kim OH,Kim H,Kang J,Yang D,Kang YH,Lee DH,Cheon GJ,Park SC,Oh BC

11-0112 was used in Flow cytometry/Cell sorting to identify age-dependent macrophage accumulation in the bone marrow, showing that ageing significantly increases the number of M1 macrophages and impairs polarisation of BMDMs.

Sun Jan 01 00:00:00 EST 2017

ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.

RNA biology

Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu May 04 00:00:00 EDT 2017

β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.

Journal of cellular biochemistry

Vafaei R,Nassiri SM,Siavashi V

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Dec 01 00:00:00 EST 2017

Impact of supplementation with a food-derived microbial community on obesity-associated inflammation and gut microbiota composition.

Genes & nutrition

Roselli M,Devirgiliis C,Zinno P,Guantario B,Finamore A,Rami R,Perozzi G

11-0112 was used in Flow cytometry/Cell sorting to study, using a mouse model, the effects of supplementary dietary microbes on obesity-associated inflammation and gut microbiota composition.

Thu Oct 01 00:00:00 EDT 2020

Growth inhibition of formed corneal neovascularization following Fosaprepitant treatment.

Acta ophthalmologica

Bignami F,Lorusso A,Rama P,Ferrari G

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Nov 01 00:00:00 EDT 2017

Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2.

Alcoholism, clinical and experimental research

Lawrimore CJ,Crews FT

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon May 01 00:00:00 EDT 2017

Differential effect of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) on leukocyte infiltration during contact hypersensitivity responses.

PeerJ

Early M,Schroeder WG,Unnithan R,Gilchrist JM,Muller WA,Schenkel A

11-0112 was used in Flow cytometry/Cell sorting to examine the role of PECAM-1 in the migration capacity of several different leukocyte populations after primary and secondary application.

Mon Dec 14 00:00:00 EST 2020

Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.

Oncotarget

Zamanian-Daryoush M,Lindner DJ,DiDonato JA,Wagner M,Buffa J,Rayman P,Parks JS,Westerterp M,Tall AR,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Sep 22 00:00:00 EDT 2017

Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment.

Scientific reports

Yeku OO,Purdon TJ,Koneru M,Spriggs D,Brentjens RJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Sep 05 00:00:00 EDT 2017

Characterisation of innate lymphoid cell populations at different sites in mice with defective T cell immunity.

Wellcome open research

Dutton EE,Camelo A,Sleeman M,Herbst R,Carlesso G,Belz GT,Withers DR

11-0112-41 was used in Flow Cytometry to compare the innate lymphoid cell populations at different sites in mice with defective T cell immunity.

Sat Jan 09 00:00:00 EST 2021

Hepatic stroma-educated regulatory DCs suppress CD8⁺ T cell proliferation in mice.

Oncotarget

Wang Q,He H,Chen D,Wang C,Xu Y,Song W

11-0112 was used in Flow cytometry/Cell sorting to assess whether and how liver dendritic cells suppress CD8+ T cells.

Tue Nov 07 00:00:00 EST 2017

MiR-125a Is a critical modulator for neutrophil development.

PLoS genetics

Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Oct 01 00:00:00 EDT 2017

Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.

Stem cell research & therapy

Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Nov 10 00:00:00 EST 2017

Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.

Oncotarget

Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Dec 12 00:00:00 EST 2017

Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling.

Oncotarget

Li CG,Yan L,Jing YY,Xu LH,Liang YD,Wei HX,Hu B,Pan H,Zha QB,Ouyang DY,He XH

11-0112 was used in Flow cytometry/Cell sorting to investigate how berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling.

Tue Jan 03 00:00:00 EST 2017

Berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling.

Oncotarget

Li CG,Yan L,Jing YY,Xu LH,Liang YD,Wei HX,Hu B,Pan H,Zha QB,Ouyang DY,He XH

11-0112 was used in Flow cytometry/Cell sorting to investigate how berberine augments ATP-induced inflammasome activation in macrophages by enhancing AMPK signaling.

Tue Jan 03 00:00:00 EST 2017

HDAC3 inhibition ameliorates spinal cord injury by immunomodulation.

Scientific reports

Kuboyama T,Wahane S,Huang Y,Zhou X,Wong JK,Koemeter-Cox A,Martini M,Friedel RH,Zou H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Thu Aug 17 00:00:00 EDT 2017

Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.

Cell death & disease

Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Jun 01 00:00:00 EDT 2017

Interleukin-1β signaling in fenestrated capillaries is sufficient to trigger sickness responses in mice.

Journal of neuroinflammation

Knoll JG,Krasnow SM,Marks DL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu Nov 09 00:00:00 EST 2017

Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.

NPJ vaccines

Stephen J,Scales HE,Benson RA,Erben D,Garside P,Brewer JM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Apr 08 00:00:00 EDT 2022

IFNGR1 signaling is associated with adverse pregnancy outcomes during infection with malaria parasites.

PloS one

Niikura M,Inoue SI,Mineo S,Asahi H,Kobayashi F

11-0112 was used in Flow cytometry/Cell sorting to explore the role of IFN-γ receptor 1 signalling in placental pathology during severe malaria using luciferase-expressing rodent malaria parasites, P. berghei NK65.

Wed Nov 29 00:00:00 EST 2017

In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.

Particle and fibre toxicology

Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Apr 14 00:00:00 EDT 2017

Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.

JCI insight

Kienhöfer D,Hahn J,Stoof J,Csepregi JZ,Reinwald C,Urbonaviciute V,Johnsson C,Maueröder C,Podolska MJ,Biermann MH,Leppkes M,Harrer T,Hultqvist M,Olofsson P,Munoz LE,Mocsai A,Herrmann M,Schett G,Holmdahl R,Hoffmann MH

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu May 18 00:00:00 EDT 2017

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation.

Nature communications

Xu Y,Wang Y,Yan S,Yang Q,Zhou Y,Zeng X,Liu Z,An X,Toque HA,Dong Z,Jiang X,Fulton DJ,Weintraub NL,Li Q,Bagi Z,Hong M,Boison D,Wu C,Huo Y

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Oct 16 00:00:00 EDT 2017

Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4.

Frontiers in microbiology

Lai CY,Strange DP,Wong TAS,Lehrer AT,Verma S

11-0112 was used in Flow cytometry/Cell sorting to investigate the early immune response to purified Ebola virus glycoprotein alone in vitro and in vivo.

Tue Sep 29 00:00:00 EDT 2020

CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4⁺ TH cells in vivo and vaccinate the host against parental MHC-II-negative tumor cells.

Oncoimmunology

Bou Nasser Eddine F,Forlani G,Lombardo L,Tedeschi A,Tosi G,Accolla RS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2021

Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6.

Science advances

Kim E,Beon J,Lee S,Park SJ,Ahn H,Kim MG,Park JE,Kim W,Yuk JM,Kang SJ,Lee SH,Jo EK,Seong RH,Kim S

11-0112 was used in Flow cytometry/Cell sorting to investigate how TRAF6 protein stability is controlled in TLR signalling, showing that Inositol polyphosphate multikinase stabilises TRAF6 and promotes TLR-induced inflammation.

Sat Apr 01 00:00:00 EDT 2017

Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.

JCI insight

Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Sep 21 00:00:00 EDT 2017

Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.

Cell

Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Oct 06 00:00:00 EDT 2016

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

Cell

Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Aug 25 00:00:00 EDT 2016

Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.

Nature immunology

Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun May 01 00:00:00 EDT 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Fri Jan 01 00:00:00 EST 2016

Oligodendrocyte death results in immune-mediated CNS demyelination.

Nature neuroscience

Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Fri Jan 01 00:00:00 EST 2016

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.

Nature cell biology

Pietras EM,Mirantes-Barbeito C,Fong S,Loeffler D,Kovtonyuk LV,Zhang S,Lakshminarasimhan R,Chin CP,Techner JM,Will B,Nerlov C,Steidl U,Manz MG,Schroeder T,Passegué E

11-0112 was used in Flow cytometry/Cell sorting to identify a critical regulatory circuit that tailors HSC responses to acute needs, and is likely to underlie deregulated blood homeostasis in chronic inflammation conditions.

Wed Jun 01 00:00:00 EDT 2016

The breast tumor microenvironment alters the phenotype and function of natural killer cells.

Cellular & molecular immunology

Krneta T,Gillgrass A,Chew M,Ashkar AA

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes.

The Journal of clinical investigation

Inoue T,Abe C,Sung SS,Moscalu S,Jankowski J,Huang L,Ye H,Rosin DL,Guyenet PG,Okusa MD

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that vagus nerve stimulation-mediated attenuation of attenuated acute kidney injury and systemic inflammation depends on α7nAChR-positive splenocytes.

Mon May 02 00:00:00 EDT 2016

Alternatively activated macrophages determine repair of the infarcted adult murine heart.

The Journal of clinical investigation

Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jun 01 00:00:00 EDT 2016

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.

Science translational medicine

Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L

11-0112 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.

Wed Nov 02 00:00:00 EDT 2016

Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells.

Leukemia

Wen S,Dooner M,Cheng Y,Papa E,Del Tatto M,Pereira M,Deng Y,Goldberg L,Aliotta J,Chatterjee D,Stewart C,Carpanetto A,Collino F,Bruno S,Camussi G,Quesenberry P

11-0112 was used in Flow cytometry/Cell sorting to evaluate the capacity of mesenchymal stromal cell-derived extracellular vesicles to rescue murine marrow hematopoietic cells damage following exposure to radiation, showing that damage could be reversed using both murine and human MSC-EVs.

Tue Nov 01 00:00:00 EDT 2016

Platelets Guide Leukocytes to Their Sites of Extravasation.

PLoS biology

Zuchtriegel G,Uhl B,Puhr-Westerheide D,Pörnbacher M,Lauber K,Krombach F,Reichel CA

11-0112 was used in Blocking experiments to uncover a platelet-directed, spatiotemporally organised, multicellular crosstalk that is essential for effective trafficking of leukocytes to the site of inflammation.

Sun May 01 00:00:00 EDT 2016

ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.

Frontiers in immunology

Zha QB,Wei HX,Li CG,Liang YD,Xu LH,Bai WJ,Pan H,He XH,Ouyang DY

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Nov 20 00:00:00 EST 2019

Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo.

Oncogene

Hobbs RP,Batazzi AS,Han MC,Coulombe PA

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu Oct 27 00:00:00 EDT 2016

Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.

Stem cells translational medicine

Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Sep 01 00:00:00 EDT 2016

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.

Immunology

Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sat Oct 01 00:00:00 EDT 2016

Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor.

Journal of cellular physiology

Li Y,Adomat H,Guns ET,Hojabrpour P,Duronio V,Curran TA,Jalili RB,Jia W,Delwar Z,Zhang Y,Elizei SS,Ghahary A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunocytochemistry

Wed Jun 01 00:00:00 EDT 2016

Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.

Journal of ginseng research

Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.

Journal of ginseng research

Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.

Disease models & mechanisms

Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Apr 01 00:00:00 EDT 2016

Lymphatic endothelial lineage assemblage during corneal lymphangiogenesis.

Laboratory investigation; a journal of technical methods and pathology

Connor AL,Kelley PM,Tempero RM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Tue Mar 01 00:00:00 EST 2016

Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.

Journal of immunology (Baltimore, Md. : 1950)

Menendez CM,Jinkins JK,Carr DJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Aug 15 00:00:00 EDT 2016

G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.

Journal of immunology (Baltimore, Md. : 1950)

Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A

11-0112 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.

Tue Nov 01 00:00:00 EDT 2016

Effects of ketanserin on experimental colitis in mice and macrophage function.

International journal of molecular medicine

Xiao J,Shao L,Shen J,Jiang W,Feng Y,Zheng P,Liu F

11-0112 was used in Flow cytometry/Cell sorting to study the effects of ketanserin on experimental colitis in mice and macrophage function.

Tue Mar 01 00:00:00 EST 2016

Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro.

Journal of immunology research

Ufimtseva E

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Tue Nov 08 00:00:00 EST 2016

ECM-Dependence of Endothelial Progenitor Cell Features.

Journal of cellular biochemistry

Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Rho kinase II interference by small hairpin RNA ameliorates 1‑methyl‑4‑phenyl‑1,2,3,6‑tetrahydropyridine‑induced parkinsonism in mice.

Molecular medicine reports

Zhang Q,Zhao YF,Xi JY,Yu WB,Xiao BG

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu Dec 01 00:00:00 EST 2016

Immunosuppression, peripheral inflammation and invasive infection from endogenous gut microbiota activate retinal microglia in mouse models.

Microbiology and immunology

Maneu V,Noailles A,Gómez-Vicente V,Carpena N,Cuenca N,Gil ML,Gozalbo D

11-0112 was used in Flow cytometry/Cell sorting to determine whether non-ocular conditions could lead to the activation of retinal microglia.

Thu Sep 01 00:00:00 EDT 2016

Sertoli cell condition medium can induce germ like cells from bone marrow derived mesenchymal stem cells.

Iranian journal of basic medical sciences

Monfared MH,Minaee B,Rastegar T,Khrazinejad E,Barbarestani M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Nov 01 00:00:00 EDT 2016

Kappa opioid receptor activation alleviates experimental autoimmune encephalomyelitis and promotes oligodendrocyte-mediated remyelination.

Nature communications

Du C,Duan Y,Wei W,Cai Y,Chai H,Lv J,Du X,Zhu J,Xie X

11-0112 was used in Flow cytometry/Cell sorting to show that kappa opioid receptor activation alleviates autoimmune encephalomyelitis and promotes remyelination..

Mon Apr 04 00:00:00 EDT 2016

Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.

Stem cell reports

Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Aug 09 00:00:00 EDT 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Fri Nov 11 00:00:00 EST 2016

Macrophages form functional vascular mimicry channels in vivo.

Scientific reports

Barnett FH,Rosenfeld M,Wood M,Kiosses WB,Usui Y,Marchetti V,Aguilar E,Friedlander M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Fri Nov 11 00:00:00 EST 2016

Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.

Cell death & disease

Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Jul 28 00:00:00 EDT 2016

Erythropoietin treatment in murine multiple myeloma: immune gain and bone loss.

Scientific reports

Deshet-Unger N,Hiram-Bab S,Haim-Ohana Y,Mittelman M,Gabet Y,Neumann D

11-0112 was used in Flow cytometry/Cell sorting to reveal that in multiple myeloma, erythropoietin may act as a double-edged sword by stimulating the immune response whilst accelerating bone resorption.

Tue Aug 02 00:00:00 EDT 2016

miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.

Nature communications

Jiang X,Hu C,Arnovitz S,Bugno J,Yu M,Zuo Z,Chen P,Huang H,Ulrich B,Gurbuxani S,Weng H,Strong J,Wang Y,Li Y,Salat J,Li S,Elkahloun AG,Yang Y,Neilly MB,Larson RA,Le Beau MM,Herold T,Bohlander SK,Liu PP,Zhang J,Li Z,He C,Jin J,Hong S,Chen J

11-0112 was used in Flow cytometry/Cell sorting to investigate the anti-tumourigenic role of miR-22, showing that it has an anti-tumour role in acute myeloid leukaemia.

Tue Apr 26 00:00:00 EDT 2016

Peripheral Leukocyte Migration in Ferrets in Response to Infection with Seasonal Influenza Virus.

PloS one

Music N,Reber AJ,Kim JH,York IA

11-0112 was used in Flow cytometry/Cell sorting to show that lymphocytes differentially home to lymph nodes and tissues based on cell type and proximity to the site of infection.

Wed Jul 12 00:00:00 EDT 2017

Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.

Oncoimmunology

Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

BubR1 Insufficiency Results in Decreased Macrophage Proliferation and Attenuated Atherogenesis in Apolipoprotein E-Deficient Mice.

Journal of the American Heart Association

Tanaka S,Matsumoto T,Matsubara Y,Harada Y,Kyuragi R,Koga JI,Egashira K,Nakashima Y,Yonemitsu Y,Maehara Y

11-0112 was used in Flow cytometry/Cell sorting to investigate the effects of BubR1 on atherosclerosis.

Sat Sep 24 00:00:00 EDT 2016

Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke.

Nature communications

Szalay G,Martinecz B,Lénárt N,Környei Z,Orsolits B,Judák L,Császár E,Fekete R,West BL,Katona G,Rózsa B,Dénes Á

11-0112 was used in Flow cytometry/Cell sorting to investigate the influence of microglia on neuronal activity and survival in the injured brain in vivo.

Tue May 03 00:00:00 EDT 2016

Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.

JCI insight

Wang Y,Golden JB,Fritz Y,Zhang X,Diaconu D,Camhi MI,Gao H,Dawes SM,Xing X,Ganesh SK,Gudjonsson JE,Simon DI,McCormick TS,Ward NL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Dec 08 00:00:00 EST 2016

Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome.

Scientific reports

Sakata K,Araki K,Nakano H,Nishina T,Komazawa-Sakon S,Murai S,Lee GE,Hashimoto D,Suzuki C,Uchiyama Y,Notohara K,Gukovskaya AS,Gukovsky I,Yamamura KI,Baba H,Ohmuraya M

11-0112 was used in Immunohistochemistry to study a novel method to rescue a lethal phenotype through integration of a target gene onto the X chromosome.

Tue Nov 15 00:00:00 EST 2016

Dendritic cell-derived nitric oxide inhibits the differentiation of effector dendritic cells.

Oncotarget

Si C,Zhang R,Wu T,Lu G,Hu Y,Zhang H,Xu F,Wei P,Chen K,Tang H,Yeretssian G,Xiong H

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that DC-derived nitric oxide restrains effector DC development to treat autoimmune and inflammatory diseases.

Tue Nov 15 00:00:00 EST 2016

Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.

Aging

McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jul 01 00:00:00 EDT 2016

NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.

Nature communications

Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Sep 07 00:00:00 EDT 2016

The impact of ranitidine on monocyte responses in the context of solid tumors.

Oncotarget

Vila-Leahey A,Rogers D,Marshall JS

11-0112 was used in Flow cytometry/Cell sorting to examine the impact of oral ranitidine treatment on multiple murine tumour models.

Tue Mar 08 00:00:00 EST 2016

Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice.

Scientific reports

Watari K,Shibata T,Nabeshima H,Shinoda A,Fukunaga Y,Kawahara A,Karasuyama K,Fukushi J,Iwamoto Y,Kuwano M,Ono M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jan 18 00:00:00 EST 2016

Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma.

Journal for immunotherapy of cancer

Patel MA,Kim JE,Theodros D,Tam A,Velarde E,Kochel CM,Francica B,Nirschl TR,Ghasemzadeh A,Mathios D,Harris-Bookman S,Jackson CC,Jackson C,Ye X,Tran PT,Tyler B,Coric V,Selby M,Brem H,Drake CG,Pardoll DM,Lim M

11-0112 was used in Flow cytometry/Cell sorting to provide preclinical evidence for the use of anti-GITR (1) non-depleting antibodies in combination with SRS in GBM.

Wed May 18 00:00:00 EDT 2016

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.

Oncoimmunology

Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Feb 01 00:00:00 EST 2016

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Scientific reports

Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jun 15 00:00:00 EDT 2016

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

Nature medicine

Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jun 01 00:00:00 EDT 2015

Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt.

Nature medicine

Wilson JE,Petrucelli AS,Chen L,Koblansky AA,Truax AD,Oyama Y,Rogers AB,Brickey WJ,Wang Y,Schneider M,Mühlbauer M,Chou WC,Barker BR,Jobin C,Allbritton NL,Ramsden DA,Davis BK,Ting JP

11-0112 was used in Flow cytometry/Cell sorting to show AIM2 regulates colon tumorigenesis by reducing activation of both DNA-PK and Akt, suggesting that Akt inhibitors could be used in treatment of certain cancers.

Sat Aug 01 00:00:00 EDT 2015

Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool.

Nature

Mesa KR,Rompolas P,Zito G,Myung P,Sun TY,Brown S,Gonzalez DG,Blagoev KB,Haberman AM,Greco V

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu Jun 04 00:00:00 EDT 2015

Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.

Nature biotechnology

Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that injected mesoporous silica rods assemble in vivo to form structures providing a 3D cellular microenvironment for host immune cells.

Thu Jan 01 00:00:00 EST 2015

High salt primes a specific activation state of macrophages, M(Na).

Cell research

Zhang WC,Zheng XJ,Du LJ,Sun JY,Shen ZX,Shi C,Sun S,Zhang Z,Chen XQ,Qin M,Liu X,Tao J,Jia L,Fan HY,Zhou B,Yu Y,Ying H,Hui L,Liu X,Yi X,Liu X,Zhang L,Duan SZ

11-0112 was used in Flow cytometry/Cell sorting to investigate the mechanisms of high salt in disease risk, showing that it primes a specific activation state of macrophages.

Sat Aug 01 00:00:00 EDT 2015

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes.

Nature genetics

Hobbs RP,DePianto DJ,Jacob JT,Han MC,Chung BM,Batazzi AS,Poll BG,Guo Y,Han J,Ong S,Zheng W,Taube JM,Čiháková D,Wan F,Coulombe PA

11-0112 was used in Flow cytometry/Cell sorting to provide new insight into keratin intermediate filament and Aire function, as well as a molecular basis for the K17-dependent amplification of inflammatory and immune responses in diseased epithelia.

Sat Aug 01 00:00:00 EDT 2015

Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia.

Cancer cell

Wu SC,Li LS,Kopp N,Montero J,Chapuy B,Yoda A,Christie AL,Liu H,Christodoulou A,van Bodegom D,van der Zwet J,Layer JV,Tivey T,Lane AA,Ryan JA,Ng SY,DeAngelo DJ,Stone RM,Steensma D,Wadleigh M,Harris M,Mandon E,Ebel N,Andraos R,Romanet V,Dölemeyer A,Sterker D,Zender M,Rodig SJ,Murakami M,Hofmann F,Kuo F,Eck MJ,Silverman LB,Sallan SE,Letai A,Baffert F,Vangrevelinghe E,Radimerski T,Gaul C,Weinstock DM

11-0112 was used in Flow cytometry/Cell sorting to support the testing of type II JAK2 inhibition in patients with JAK2-dependent leukemias and other disorders.

Mon Jul 13 00:00:00 EDT 2015

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Cell metabolism

Lodhi IJ,Wei X,Yin L,Feng C,Adak S,Abou-Ezzi G,Hsu FF,Link DC,Semenkovich CF

11-0112 was used in Flow cytometry/Cell sorting to investigate the immunometabolism pathway by which peroxisomal lipid synthesis regulates neutrophil development and inflammation.

Tue Jan 06 00:00:00 EST 2015

Host microbiota constantly control maturation and function of microglia in the CNS.

Nature neuroscience

Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Blood

Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Nov 19 00:00:00 EST 2015

CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.

Cell stem cell

Iwasaki M,Liedtke M,Gentles AJ,Cleary ML

11-0112 was used in Flow cytometry/Cell sorting to study how CD93 expression may indicate leukaemia initiating stem cells that have a MLL gene rearrangement.

Thu Oct 01 00:00:00 EDT 2015

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.

The Journal of clinical investigation

Fond AM,Lee CS,Schulman IG,Kiss RS,Ravichandran KS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jul 01 00:00:00 EDT 2015

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.

The Journal of clinical investigation

Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.

The Journal of clinical investigation

Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Dec 01 00:00:00 EST 2015

STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.

The Journal of clinical investigation

Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Nov 02 00:00:00 EST 2015

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.

Brain : a journal of neurology

Natrajan MS,de la Fuente AG,Crawford AH,Linehan E,Nuñez V,Johnson KR,Wu T,Fitzgerald DC,Ricote M,Bielekova B,Franklin RJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Dec 01 00:00:00 EST 2015

Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.

Journal of the American Society of Nephrology : JASN

Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Cis-regulatory mechanisms governing stem and progenitor cell transitions.

Science advances

Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response.

EMBO molecular medicine

Chan JK,Glass GE,Ersek A,Freidin A,Williams GA,Gowers K,Espirito Santo AI,Jeffery R,Otto WR,Poulsom R,Feldmann M,Rankin SM,Horwood NJ,Nanchahal J

11-0112 was used in Flow cytometry/Cell sorting to investigate the optimal treatment course of low-dose recombinant human TNF to augment bone fracture repair in a mouse model, and the major cells involved.

Fri May 01 00:00:00 EDT 2015

Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.

Cancer research

Kratochvill F,Gratz N,Qualls JE,Van De Velde LA,Chi H,Kovarik P,Murray PJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Western Blot

Sat Aug 01 00:00:00 EDT 2015

The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes.

Proceedings of the National Academy of Sciences of the United States of America

Collins PL,Kyle KE,Egawa T,Shinkai Y,Oltz EM

11-0112 was used in Flow cytometry/Cell sorting to investigate mechanisms of endogenous retrovirus repression in differentiated cells.

Tue Jul 07 00:00:00 EDT 2015

COX/mPGES-1/PGE2 pathway depicts an inflammatory-dependent high-risk neuroblastoma subset.

Proceedings of the National Academy of Sciences of the United States of America

Larsson K,Kock A,Idborg H,Arsenian Henriksson M,Martinsson T,Johnsen JI,Korotkova M,Kogner P,Jakobsson PJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Tue Jun 30 00:00:00 EDT 2015

Mast cells boost myeloid-derived suppressor cell activity and contribute to the development of tumor-favoring microenvironment.

Cancer immunology research

Danelli L,Frossi B,Gri G,Mion F,Guarnotta C,Bongiovanni L,Tripodo C,Mariuzzi L,Marzinotto S,Rigoni A,Blank U,Colombo MP,Pucillo CE

11-0112 was used in Flow cytometry/Cell sorting to examine the interactions between myeloid-derived suppressor cells and mast cells in the mucosa of patients with colon carcinoma.

Thu Jan 01 00:00:00 EST 2015

Spatiotemporal expression dynamics of selectins govern the sequential extravasation of neutrophils and monocytes in the acute inflammatory response.

Arteriosclerosis, thrombosis, and vascular biology

Zuchtriegel G,Uhl B,Hessenauer ME,Kurz AR,Rehberg M,Lauber K,Krombach F,Reichel CA

11-0112 was used in Flow cytometry/Cell sorting to provide novel insights into the mechanisms initiating the sequential infiltration of the perivascular tissue by neutrophils and monocytes in the acute inflammatory response.

Wed Apr 01 00:00:00 EDT 2015

Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases.

Breast cancer research : BCR

Tabariès S,Ouellet V,Hsu BE,Annis MG,Rose AA,Meunier L,Carmona E,Tam CE,Mes-Masson AM,Siegel PM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Fri Mar 27 00:00:00 EDT 2015

Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.

Glia

Verheijden S,Beckers L,Casazza A,Butovsky O,Mazzone M,Baes M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Aging-like changes in the transcriptome of irradiated microglia.

Glia

Li MD,Burns TC,Kumar S,Morgan AA,Sloan SA,Palmer TD

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri May 01 00:00:00 EDT 2015

Limited Efficacy of Antibacterial Vaccination Against Secondary Serotype 3 Pneumococcal Pneumonia Following Influenza Infection.

The Journal of infectious diseases

Metzger DW,Furuya Y,Salmon SL,Roberts S,Sun K

11-0112 was used in Flow cytometry/Cell sorting to show that antibacterial vaccination is only partially effective in protection against secondary serotype 3 pneumococcal pneumonia following influenza.

Sat Aug 01 00:00:00 EDT 2015

Premature thymic involution is independent of structural plasticity of the thymic stroma.

European journal of immunology

Franckaert D,Schlenner SM,Heirman N,Gill J,Skogberg G,Ekwall O,Put K,Linterman MA,Dooley J,Liston A

11-0112 was used in Flow cytometry/Cell sorting to investigate thymic involution in FVB/N mice, showing that disruption of the epithelial-endothelial relationship and a progressive loss of pro-T cells precedes involution, and loss of pro-T cells is sufficient to drive premature involution, suggesting that pro-T cells are the main driver of involution.

Fri May 01 00:00:00 EDT 2015

Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine.

Cancer science

Ohshio Y,Teramoto K,Hanaoka J,Tezuka N,Itoh Y,Asai T,Daigo Y,Ogasawara K

11-0112 was used in Flow cytometry/Cell sorting to study the immunosuppressive trait of CAFs, and systematically explore the alteration of tumour-associated immune responses by CAF-targeted therapy.

Sun Feb 01 00:00:00 EST 2015

Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine.

Cancer science

Ohshio Y,Teramoto K,Hanaoka J,Tezuka N,Itoh Y,Asai T,Daigo Y,Ogasawara K

11-0112 was used in Flow cytometry/Cell sorting to study the immunosuppressive trait of CAFs, and systematically explore the alteration of tumour-associated immune responses by CAF-targeted therapy.

Sun Feb 01 00:00:00 EST 2015

Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent.

American journal of physiology. Lung cellular and molecular physiology

Orr SK,Colas RA,Dalli J,Chiang N,Serhan CN

11-0112 was used in Flow cytometry/Cell sorting to investigate a synthetic analogue of resolvin D1 and asprin-triggered BDA-resolvin D1.

Fri May 01 00:00:00 EDT 2015

Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a Staphylococcus aureus dermonecrosis model.

Antimicrobial agents and chemotherapy

Hilliard JJ,Datta V,Tkaczyk C,Hamilton M,Sadowska A,Jones-Nelson O,O'Day T,Weiss WJ,Szarka S,Nguyen V,Prokai L,Suzich J,Stover CK,Sellman BR

11-0112 was used in Flow cytometry/Cell sorting to characterise MEDI4893* and its therapeutic activity in a dermonecrosis model, showing that MEDI4893* and antibiotic combination therapy improves disease outcome.

Thu Jan 01 00:00:00 EST 2015

Spred1, a Suppressor of the Ras-ERK Pathway, Negatively Regulates Expansion and Function of Group 2 Innate Lymphoid Cells.

Journal of immunology (Baltimore, Md. : 1950)

Suzuki M,Morita R,Hirata Y,Shichita T,Yoshimura A

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that Spred1, a negative regulator of the Ras-ERK pathway, plays an important role in the proliferation and apoptosis of ILC2s and in cytokine secretion from ILC2s.

Sat Aug 01 00:00:00 EDT 2015

mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function.

Journal of immunology (Baltimore, Md. : 1950)

Schaffert SA,Loh C,Wang S,Arnold CP,Axtell RC,Newell EW,Nolan G,Ansel KM,Davis MM,Steinman L,Chen CZ

11-0112 was used in Flow cytometry/Cell sorting to explore the physiological control of tolerance by manipulating microRNA gene products.

Sat Aug 15 00:00:00 EDT 2015

Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro.

Cell transplantation

Nakatsuka R,Matsuoka Y,Uemura Y,Sumide K,Iwaki R,Takahashi M,Fujioka T,Sasaki Y,Sonoda Y

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that prospectively isolated murine PDGFRα and Sca-1 double-positive dental pulp stem cells could support primitive human CD34+ and CD34- hematopoietic stem cells in vitro.

Wed Sep 16 00:00:00 EDT 2015

Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.

Tissue engineering. Part A

Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Apr 01 00:00:00 EDT 2015

Toll-Like receptor 2 (TLR2) and TLR9 play opposing roles in host innate immunity against Salmonella enterica serovar Typhimurium infection.

Infection and immunity

Zhan R,Han Q,Zhang C,Tian Z,Zhang J

11-0112 was used in Flow cytometry/Cell sorting to investigate the roles of TLR2 and TLR9 in regulating innate immunity against oral infection of Salmonella enterica serovar Typhimurium in mice.

Wed Apr 01 00:00:00 EDT 2015

Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.

Molecular medicine reports

Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Sep 01 00:00:00 EDT 2015

Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.

BioMed research international

Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Aug 01 00:00:00 EDT 2016

Mesenchymal stem cells can prevent alterations in behavior and neurogenesis induced by Aß25-35 administration.

Journal of molecular neuroscience : MN

Hamisha KN,Tfilin M,Yanai J,Turgeman G

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Wed Apr 01 00:00:00 EDT 2015

Injectable cryogel-based whole-cell cancer vaccines.

Nature communications

Bencherif SA,Warren Sands R,Ali OA,Li WA,Lewin SA,Braschler TM,Shih TY,Verbeke CS,Bhatta D,Dranoff G,Mooney DJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Aug 12 00:00:00 EDT 2015

Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development.

Scientific reports

Frodermann V,van Duijn J,van Pel M,van Santbrink PJ,Bot I,Kuiper J,de Jager SC

11-0112 was used in Flow cytometry/Cell sorting to study how MSC treatment affects not only inflammatory responses but also significantly reduces dyslipidaemia in mice.

Thu Oct 22 00:00:00 EDT 2015

Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.

Nature communications

Kanno A,Tanimura N,Ishizaki M,Ohko K,Motoi Y,Onji M,Fukui R,Shimozato T,Yamamoto K,Shibata T,Sano S,Sugahara-Tobinai A,Takai T,Ohto U,Shimizu T,Saitoh S,Miyake K

11-0112 was used in Flow cytometry/Cell sorting to show that Toll-like receptor 7 (TLR7) is present on the cell surface of immune cells and that TLR7 responses can be inhibited by an anti-TLR7 antibody.

Wed Feb 04 00:00:00 EST 2015

Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.

The Journal of biological chemistry

Pamir N,Liu NC,Irwin A,Becker L,Peng Y,Ronsein GE,Bornfeldt KE,Duffield JS,Heinecke JW

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jun 05 00:00:00 EDT 2015

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.

Nature communications

Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Mar 20 00:00:00 EDT 2015

Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation.

Nature communications

Polte T,Petzold S,Bertrand J,Schütze N,Hinz D,Simon JC,Lehmann I,Echtermeyer F,Pap T,Averbeck M

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that SDC4 plays an important role in asthma induction and indicate SDC4 as a possible target for therapeutic intervention in this disease.

Mon Jul 13 00:00:00 EDT 2015

Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis.

PloS one

Kim WS,Kim JS,Cha SB,Han SJ,Kim H,Kwon KW,Kim SJ,Eum SY,Cho SN,Shin SJ

11-0112 was used in Blocking experiments to compare the bacterial burden, inflammation and kinetics of immune cells during aerogenic infection in the lung between laboratory-adapted strains (Mtb H37Rv and H37Ra) and Mtb K strain.

Mon Jun 27 00:00:00 EDT 2016

Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis.

PloS one

Kim WS,Kim JS,Cha SB,Han SJ,Kim H,Kwon KW,Kim SJ,Eum SY,Cho SN,Shin SJ

Mon Jun 27 00:00:00 EDT 2016

Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.

Nature communications

Balasubramani A,Larjo A,Bassein JA,Chang X,Hastie RB,Togher SM,Lähdesmäki H,Rao A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jun 22 00:00:00 EDT 2015

Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.

PloS one

Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jan 12 00:00:00 EST 2016

dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.

Nature communications

Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Sep 15 00:00:00 EDT 2015

Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.

Stem cell reports

Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Oct 13 00:00:00 EDT 2015

Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.

PloS one

Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue May 10 00:00:00 EDT 2016

Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.

PloS one

Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue May 10 00:00:00 EDT 2016

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization.

Nature communications

Lu G,Zhang R,Geng S,Peng L,Jayaraman P,Chen C,Xu F,Yang J,Li Q,Zheng H,Shen K,Wang J,Liu X,Wang W,Zheng Z,Qi CF,Si C,He JC,Liu K,Lira SA,Sikora AG,Li L,Xiong H

11-0112 was used in Flow cytometry/Cell sorting to show that iNOS-deficient mice display enhanced classically activated M1 macrophage polarization without major effects on alternatively activated M2 macrophages.

Fri Mar 27 00:00:00 EDT 2015

Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.

The Journal of biological chemistry

Chen R,Zhang K,Chen H,Zhao X,Wang J,Li L,Cong Y,Ju Z,Xu D,Williams BR,Jia J,Liu JP

11-0112 was used in Flow cytometry/Cell sorting to elucidate the mechanisms by which TERC and TERT participate in lung diseases.

Fri Dec 25 00:00:00 EST 2015

Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice.

PloS one

Kumagai K,Tabu K,Sasaki F,Takami Y,Morinaga Y,Mawatari S,Hashimoto S,Tanoue S,Kanmura S,Tamai T,Moriuchi A,Uto H,Tsubouchi H,Ido A

11-0112 was used in Flow cytometry/Cell sorting to identify the immune cells which respond to acute liver injury and assess their contribution to the repair process.

Mon Jun 20 00:00:00 EDT 2016

Interleukin-15 Constrains Mucosal T Helper 17 Cell Generation: Influence of Mononuclear Phagocytes.

PloS one

Yu H,Sui Y,Wang Y,Sato N,Frey B,Xia Z,Waldmann TA,Berzofsky J

11-0112 was used in Flow cytometry/Cell sorting to investigate the role of IL-15 in regulating differentiation of T helper cell subsets, showing that it constrains mucosal T helper 17 cell generation.

Mon Jun 20 00:00:00 EDT 2016

Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.

Oncoimmunology

Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Mar 01 00:00:00 EST 2015

DNase II-dependent DNA digestion is required for DNA sensing by TLR9.

Nature communications

Chan MP,Onji M,Fukui R,Kawane K,Shibata T,Saitoh S,Ohto U,Shimizu T,Barber GN,Miyake K

11-0112 was used in Flow cytometry/Cell sorting to study the response to two types of TLR9 ligands in the dendritic cells of DNase II-deficient mice.

Tue Jan 20 00:00:00 EST 2015

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity.

Nature

Westphalen K,Gusarova GA,Islam MN,Subramanian M,Cohen TS,Prince AS,Bhattacharya J

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Thu Feb 27 00:00:00 EST 2014

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.

Nature

Colegio OR,Chu NQ,Szabo AL,Chu T,Rhebergen AM,Jairam V,Cyrus N,Brokowski CE,Eisenbarth SC,Phillips GM,Cline GW,Phillips AJ,Medzhitov R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Sep 25 00:00:00 EDT 2014

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.

Cell

Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Mar 13 00:00:00 EDT 2014

Adenylyl cyclase-associated protein 1 is a receptor for human resistin and mediates inflammatory actions of human monocytes.

Cell metabolism

Lee S,Lee HC,Kwon YW,Lee SE,Cho Y,Kim J,Lee S,Kim JY,Lee J,Yang HM,Mook-Jung I,Nam KY,Chung J,Lazar MA,Kim HS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Tue Mar 04 00:00:00 EST 2014

A role for the ITAM signaling module in specifying cytokine-receptor functions.

Nature immunology

Bezbradica JS,Rosenstein RK,DeMarco RA,Brodsky I,Medzhitov R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Apr 01 00:00:00 EDT 2014

Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation.

The Journal of clinical investigation

Li J,Razumilava N,Gores GJ,Walters S,Mizuochi T,Mourya R,Bessho K,Wang YH,Glaser SS,Shivakumar P,Bezerra JA

11-0112 was used in Flow cytometry/Cell sorting to demonstrate the role of the Th2-promoting cytokine, IL-33, in cholangiocyte proliferation.

Tue Jul 01 00:00:00 EDT 2014

Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis.

Science translational medicine

Fletcher AL,Elman JS,Astarita J,Murray R,Saeidi N,D'Rozario J,Knoblich K,Brown FD,Schildberg FA,Nieves JM,Heng TS,Boyd RL,Turley SJ,Parekkadan B

11-0112 was used in Flow cytometry/Cell sorting to characterise a novel population of immune-specialised myofibroblasts derived from lymph node tissue, termed fibroblastic reticular cells.

Wed Aug 13 00:00:00 EDT 2014

Myeloid-derived suppressor cell function is diminished in aspirin-triggered allergic airway hyperresponsiveness in mice.

The Journal of allergy and clinical immunology

Shi M,Shi G,Tang J,Kong D,Bao Y,Xiao B,Zuo C,Wang T,Wang Q,Shen Y,Wang H,Funk CD,Zhou J,Yu Y

11-0112 was used in Flow cytometry/Cell sorting to characterise myeloid-derived suppressor cell accumulation and pathogenic functions in allergic airway inflammation mediated by COX-1 deficiency or aspirin treatment in mice.

Sat Nov 01 00:00:00 EDT 2014

Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer.

Autophagy

Guo W,Sun Y,Liu W,Wu X,Guo L,Cai P,Wu X,Wu X,Shen Y,Shu Y,Gu Y,Xu Q

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Sun Jun 01 00:00:00 EDT 2014

RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma.

Cancer research

Chen X,Zhang L,Zhang IY,Liang J,Wang H,Ouyang M,Wu S,da Fonseca ACC,Weng L,Yamamoto Y,Yamamoto H,Natarajan R,Badie B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Dec 15 00:00:00 EST 2014

Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis.

Aging cell

Linehan E,Dombrowski Y,Snoddy R,Fallon PG,Kissenpfennig A,Fitzgerald DC

11-0112 was used in Flow cytometry/Cell sorting to determine that age-related defects in macrophage phagocytosis may be due to extrinsic factors in the tissue microenvironment.

Fri Aug 01 00:00:00 EDT 2014

Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis.

Aging cell

Linehan E,Dombrowski Y,Snoddy R,Fallon PG,Kissenpfennig A,Fitzgerald DC

11-0112 was used in Flow cytometry/Cell sorting to determine that age-related defects in macrophage phagocytosis may be due to extrinsic factors in the tissue microenvironment.

Fri Aug 01 00:00:00 EDT 2014

S100a8/a9 released by CD11b+Gr1+ neutrophils activates cardiac fibroblasts to initiate angiotensin II-Induced cardiac inflammation and injury.

Hypertension (Dallas, Tex. : 1979)

Wu Y,Li Y,Zhang C,A X,Wang Y,Cui W,Li H,Du J

11-0112 was used in Flow cytometry/Cell sorting to elucidate the initial factors that trigger the inflammatory cascade during angiotensin II-induced cardiovascular injury.

Sun Jun 01 00:00:00 EDT 2014

Macrophages contribute to the cyclic activation of adult hair follicle stem cells.

PLoS biology

Castellana D,Paus R,Perez-Moreno M

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Dec 01 00:00:00 EST 2014

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Tue Aug 12 00:00:00 EDT 2014

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma.

Science signaling

Kusne Y,Carrera-Silva EA,Perry AS,Rushing EJ,Mandell EK,Dietrich JD,Errasti AE,Gibbs D,Berens ME,Loftus JC,Hulme C,Yang W,Lu Z,Aldape K,Sanai N,Rothlin CV,Ghosh S

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Tue Aug 12 00:00:00 EDT 2014

Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.

Glia

Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Aug 01 00:00:00 EDT 2014

Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells.

Journal of tissue engineering

Mukonoweshuro B,Brown CJ,Fisher J,Ingham E

11-0112 was used in Flow cytometry/Cell sorting to determine that although mesenchymal stem cells possess immunosuppressive properties, they may not be immunoprivileged.

Fri May 09 00:00:00 EDT 2014

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.

Development (Cambridge, England)

Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Jun 01 00:00:00 EDT 2014

Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Howerton AR,Roland AV,Bale TL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Wed May 21 00:00:00 EDT 2014

Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease.

American journal of physiology. Lung cellular and molecular physiology

Lee R,Reese C,Bonner M,Tourkina E,Hajdu Z,Riemer EC,Silver RM,Visconti RP,Hoffman S

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Tue Apr 15 00:00:00 EDT 2014

Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor.

Stem cells (Dayton, Ohio)

Povinelli BJ,Nemeth MJ

11-0112 was used in Flow cytometry/Cell sorting to study whether Ryk protein regulates the response of haematopoietic stem cells to Wnt5a.

Wed Jan 01 00:00:00 EST 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu May 01 00:00:00 EDT 2014

Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.

Stem cells (Dayton, Ohio)

Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu May 01 00:00:00 EDT 2014

Hepatic stellate cells promote tumor progression by enhancement of immunosuppressive cells in an orthotopic liver tumor mouse model.

Laboratory investigation; a journal of technical methods and pathology

Zhao W,Zhang L,Xu Y,Zhang Z,Ren G,Tang K,Kuang P,Zhao B,Yin Z,Wang X

11-0112 was used in Flow cytometry/Cell sorting to study the complex tumor-host interactions in hepatocellular carcinoma, specifically how the immunosuppressive properties of hepatic stellate cells may contribute to hepatocellular carcinoma occurrence and development..

Sat Feb 01 00:00:00 EST 2014

Dynamic changes in macrophage activation and proliferation during the development and resolution of intestinal inflammation.

Journal of immunology (Baltimore, Md. : 1950)

Little MC,Hurst RJ,Else KJ

11-0112 was used in Flow cytometry/Cell sorting to study intestinal inflammation and the dynamic changes in macrophage activation and proliferation that occur during this process.

Sat Nov 01 00:00:00 EDT 2014

Cutting edge: CD8+ recent thymic emigrants exhibit increased responses to low-affinity ligands and improved access to peripheral sites of inflammation.

Journal of immunology (Baltimore, Md. : 1950)

Berkley AM,Fink PJ

11-0112-41 was used in Flow Cytometry to investigate if the maturation state of peripheral T cells impacts the response to bacterial infection due to intrinsic differences in TCR signaling.

Wed Oct 01 00:00:00 EDT 2014

Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection.

Journal of immunology (Baltimore, Md. : 1950)

Jie Z,Liang Y,Hou L,Dong C,Iwakura Y,Soong L,Cong Y,Sun J

11-0112 was used in Flow cytometry/Cell sorting to investigate the source and regulation of the IL-17 surge in the liver microenvironment that occurs early in the response to viral infection.

Tue Apr 01 00:00:00 EDT 2014

Oral combined therapy with probiotics and alloantigen induces B cell-dependent long-lasting specific tolerance.

Journal of immunology (Baltimore, Md. : 1950)

Mercadante AC,Perobelli SM,Alves AP,Gonçalves-Silva T,Mello W,Gomes-Santos AC,Miyoshi A,Azevedo V,Faria AM,Bonomo A

11-0112 was used in Flow cytometry/Cell sorting to suggest that combined therapy is a promising strategy for prevention of GVHD with preservation of graft-versus-leukemia in allogenic HSCT.

Sat Feb 15 00:00:00 EST 2014

Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.

Journal of immunology (Baltimore, Md. : 1950)

El-Zaatari M,Chang YM,Zhang M,Franz M,Shreiner A,McDermott AJ,van der Sluijs KF,Lutter R,Grasberger H,Kamada N,Young VB,Huffnagle GB,Kao JY

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Jul 15 00:00:00 EDT 2014

Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.

Journal of immunology (Baltimore, Md. : 1950)

Jiao J,Dragomir AC,Kocabayoglu P,Rahman AH,Chow A,Hashimoto D,Leboeuf M,Kraus T,Moran T,Carrasco-Avino G,Friedman SL,Merad M,Aloman C

11-0112 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cells in neutrophil homeostasis, showing a central role in regulation of bone marrow release and survival of neutrophils.

Tue Apr 01 00:00:00 EDT 2014

Anti-inflammatory functions of protein C require RAGE and ICAM-1 in a stimulus-dependent manner.

Mediators of inflammation

Braach N,Buschmann K,Pflaum J,Hudalla H,Koch L,Ryschich E,Poeschl J,Frommhold D

11-0112 was used in Flow cytometry/Cell sorting to show that RAGE and ICAM-1 are cooperatively involved in protein C-induced inhibition of leukocyte recruitment.

Sat Feb 07 00:00:00 EST 2015

Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages.

Journal of neuroimmunology

Carvalho da Fonseca AC,Wang H,Fan H,Chen X,Zhang I,Zhang L,Lima FR,Badie B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Sep 15 00:00:00 EDT 2014

HIF-α/MIF and NF-κB/IL-6 axes contribute to the recruitment of CD11b+Gr-1+ myeloid cells in hypoxic microenvironment of HNSCC.

Neoplasia (New York, N.Y.)

Zhu G,Tang Y,Geng N,Zheng M,Jiang J,Li L,Li K,Lei Z,Chen W,Fan Y,Ma X,Li L,Wang X,Liang X

11-0112 was used in Flow cytometry/Cell sorting to reveal HIF-α/MIF and NF-κB/IL-6 interaction plays a role in hypoxia-induced accumulation of CD11b+Gr-1+ myeloid cells and tumour growth.

Sat Feb 01 00:00:00 EST 2014

Regulation of methylglyoxal-elicited leukocyte recruitment by endothelial SGK1/GSK3 signaling.

Biochimica et biophysica acta

Su Y,Qadri SM,Cayabyab FS,Wu L,Liu L

11-0112 was used in Flow cytometry/Cell sorting to investigate the signal transduction of leukocyte- and endothelial-expressed PI3K, GSK3 and SGK1 in the regulation of methylglyoxal-elicited leukocyte recruitment.

Sat Nov 01 00:00:00 EDT 2014

Influenza vaccination accelerates recovery of ferrets from lymphopenia.

PloS one

Music N,Reber AJ,Lipatov AS,Kamal RP,Blanchfield K,Wilson JR,Donis RO,Katz JM,York IA

11-0112 was used in Flow cytometry/Cell sorting to assess the effectiveness of the influenza vaccine in restoring normal blood cell levels.

Wed Oct 07 00:00:00 EDT 2015

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.

Nature communications

Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Oct 28 00:00:00 EDT 2014

Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice.

PloS one

Coquery CM,Wade NS,Loo WM,Kinchen JM,Cox KM,Jiang C,Tung KS,Erickson LD

11-0112 was used in Immunohistochemistry to analyse the phenotype, localisation and function of neutrophils in the spleens of healthy mice and congenic lupus-prone mice.

Fri Nov 06 00:00:00 EST 2015

Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice.

PloS one

Coquery CM,Wade NS,Loo WM,Kinchen JM,Cox KM,Jiang C,Tung KS,Erickson LD

11-0112 was used in Immunohistochemistry to analyse the phenotype, localisation and function of neutrophils in the spleens of healthy mice and congenic lupus-prone mice.

Fri Nov 06 00:00:00 EST 2015

Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.

PloS one

Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu May 28 00:00:00 EDT 2015

Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock.

PloS one

Hou H,Liu W,Wu S,Lu Y,Peng J,Zhu Y,Lu Y,Wang F,Sun Z

11-0112 was used in Flow cytometry/Cell sorting to study the role of Tim-3 in the regulation of natural killer cells following LPS-induced shock.

Mon Jul 06 00:00:00 EDT 2015

Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.

Molecular cancer

Doloff JC,Chen CS,Waxman DJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Jun 26 00:00:00 EDT 2014

STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.

Nature communications

Zhang H,Hu H,Greeley N,Jin J,Matthews AJ,Ohashi E,Caetano MS,Li HS,Wu X,Mandal PK,McMurray JS,Moghaddam SJ,Sun SC,Watowich SS

11-0112 was used in Flow cytometry/Cell sorting to investigate the mechanism by which STAT3 curbs pro-inflammatory cytokine production mediated by NF-κB signalling, showing that it restrains signalling by suppressing expression of Ubc13.

Mon Dec 15 00:00:00 EST 2014

Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.

PloS one

Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Wed Jun 10 00:00:00 EDT 2015

P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.

PloS one

Monção-Ribeiro LC,Faffe DS,Santana PT,Vieira FS,da Graça CL,Marques-da-Silva C,Machado MN,Caruso-Neves C,Zin WA,Borojevic R,Takiya CM,Coutinho-Silva R

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Sep 17 00:00:00 EDT 2015

Brugia malayi microfilariae induce a regulatory monocyte/macrophage phenotype that suppresses innate and adaptive immune responses.

PLoS neglected tropical diseases

O'Regan NL,Steinfelder S,Venugopal G,Rao GB,Lucius R,Srikantam A,Hartmann S

11-0112 was used in Flow cytometry/Cell sorting to show that monocytes stimulated with Brugia malayi microfilarial lysate develop a defined regulatory phenotype.

Wed Oct 01 00:00:00 EDT 2014

p85α recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression.

Nature communications

Tian L,Choi SC,Murakami Y,Allen J,Morse HC,Qi CF,Krzewski K,Coligan JE

11-0112 was used in Flow cytometry/Cell sorting to identify the mechanism and role of mouse CD300f in apoptotic cell phagocytosis and the maintenance of immune homeostasis.

Mon Mar 07 00:00:00 EST 2016

The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.

The Journal of biological chemistry

Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Feb 14 00:00:00 EST 2014

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.

Nature cell biology

Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Mar 01 00:00:00 EST 2013

S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages.

Clinical cancer research : an official journal of the American Association for Cancer Research

Wang H,Zhang L,Zhang IY,Chen X,Da Fonseca A,Wu S,Ren H,Badie S,Sadeghi S,Ouyang M,Warden CD,Badie B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Jul 15 00:00:00 EDT 2013

A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils.

Developmental cell

Zhang Y,Tang W,Zhang H,Niu X,Xu Y,Zhang J,Gao K,Pan W,Boggon TJ,Toomre D,Min W,Wu D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Oct 28 00:00:00 EDT 2013

Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.

Journal of lipid research

Camacho M,Dilmé J,Solà-Villà D,Rodríguez C,Bellmunt S,Siguero L,Alcolea S,Romero JM,Escudero JR,Martínez-González J,Vila L

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Sun Dec 01 00:00:00 EST 2013

Novel apidaecin 1b analogs with superior serum stabilities for treatment of infections by gram-negative pathogens.

Antimicrobial agents and chemotherapy

Berthold N,Czihal P,Fritsche S,Sauer U,Schiffer G,Knappe D,Alber G,Hoffmann R

11-0112 was used in Flow cytometry/Cell sorting to study the effect of modifications to the C-terminus of Api88 on its rate of proteolysis.

Tue Jan 01 00:00:00 EST 2013

Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase.

Laboratory investigation; a journal of technical methods and pathology

Hull TD,Bolisetty S,DeAlmeida AC,Litovsky SH,Prabhu SD,Agarwal A,George JF

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that HO-1 induction prevents the depression of cardiac function imposed by Cre-induced cardiac toxicity.

Thu Aug 01 00:00:00 EDT 2013

Mast cell-deficient Kit(W-sh) "Sash" mutant mice display aberrant myelopoiesis leading to the accumulation of splenocytes that act as myeloid-derived suppressor cells.

Journal of immunology (Baltimore, Md. : 1950)

Michel A,Schüler A,Friedrich P,Döner F,Bopp T,Radsak M,Hoffmann M,Relle M,Distler U,Kuharev J,Tenzer S,Feyerabend TB,Rodewald HR,Schild H,Schmitt E,Becker M,Stassen M

11-0112 was used in Flow cytometry/Cell sorting to demonstrate the broad effects that the Kit(W-sh) mutation has on key steps in myelopoiesis.

Sat Jun 01 00:00:00 EDT 2013

Gene expression changes in aging retinal microglia: relationship to microglial support functions and regulation of activation.

Neurobiology of aging

Ma W,Cojocaru R,Gotoh N,Gieser L,Villasmil R,Cogliati T,Swaroop A,Wong WT

11-0112 was used in Flow cytometry/Cell sorting to investigate age-related changes in gene expression patterns in microglia.

Tue Oct 01 00:00:00 EDT 2013

Pharmacological inhibition of p38 mitogen-activated protein kinases affects KC/CXCL1-induced intraluminal crawling, transendothelial migration, and chemotaxis of neutrophils in vivo.

Mediators of inflammation

Xu N,Hossain M,Liu L

11-0112 was used in Flow cytometry/Cell sorting to study the effect of a p38 MAPK inhibitor on Mac-1 expression in neutrophils after stimulation with chemokine KC.

Mon Aug 19 00:00:00 EDT 2013

Uterine natural killer cells severely decrease in number at gestation day 6 in mice.

Biology of reproduction

Takashima A,Ishikawa F,Kuwabara T,Tanaka Y,Kinoshita T,Ito M,Kakiuchi T

11-0112 was used in Flow cytometry/Cell sorting to study how uterine NK cells or their precursors migrate into the uterus, mature, and produce interferon-gamma to support pregnancy in mice.

Tue Oct 01 00:00:00 EDT 2013

Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.

American journal of physiology. Renal physiology

Li S,Mariappan N,Megyesi J,Shank B,Kannan K,Theus S,Price PM,Duffield JS,Portilla D

11-0112 was used in Flow cytometry/Cell sorting to study how proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.

Sun Sep 01 00:00:00 EDT 2013

Kinetics of neutrophils in mice exposed to radiation and/or granulocyte colony-stimulating factor treatment.

Radiation research

Romero-Weaver AL,Wan XS,Diffenderfer ES,Lin L,Kennedy AR

11-0112 was used in Flow cytometry/Cell sorting to evaluate the involvement of SPE-like protons and γ radiation on neutropenia observed in astronauts following radiation exposure using a mouse model system.

Thu Aug 01 00:00:00 EDT 2013

Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration.

The Journal of comparative neurology

Lampron A,Pimentel-Coelho PM,Rivest S

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Sun Dec 01 00:00:00 EST 2013

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.

The Journal of biological chemistry

Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Fri Jul 19 00:00:00 EDT 2013

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.

The Journal of biological chemistry

Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Fri Jul 19 00:00:00 EDT 2013

Staphylococcus aureus alpha toxin suppresses effective innate and adaptive immune responses in a murine dermonecrosis model.

PloS one

Tkaczyk C,Hamilton MM,Datta V,Yang XP,Hilliard JJ,Stephens GL,Sadowska A,Hua L,O'Day T,Suzich J,Stover CK,Sellman BR

11-0112 was used in Flow cytometry/Cell sorting to investigate the effect of alpha toxin on the immune response against soft tissue infections, showing that alpha toxin suppresses effective innate and adaptive immune responses.

Mon Jun 23 00:00:00 EDT 2014

A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype.

Virology journal

Ellis BL,Hirsch ML,Barker JC,Connelly JP,Steininger RJ,Porteus MH

11-0112 was used in Flow cytometry/Cell sorting to produce a comprehensive study of the transduction efficiency of viral vectors.

Wed Mar 06 00:00:00 EST 2013

Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.

The Journal of biological chemistry

Fernandez-Castaneda A,Arandjelovic S,Stiles TL,Schlobach RK,Mowen KA,Gonias SL,Gaultier A

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Feb 15 00:00:00 EST 2013

Lack of endogenous IL-10 enhances production of proinflammatory cytokines and leads to Brucella abortus clearance in mice.

PloS one

Corsetti PP,de Almeida LA,Carvalho NB,Azevedo V,Silva TM,Teixeira HC,Faria AC,Oliveira SC

11-0112 was used in Flow cytometry/Cell sorting to evaluate the contribution of IL-10 in host immune response and pathology during B. abortus infection.

Sun Jun 15 00:00:00 EDT 2014

γδ T cells recognize a microbial encoded B cell antigen to initiate a rapid antigen-specific interleukin-17 response.

Immunity

Zeng X,Wei YL,Huang J,Newell EW,Yu H,Kidd BA,Kuhns MS,Waters RW,Davis MM,Weaver CT,Chien YH

11-0112 was used in Flow cytometry/Cell sorting to study the γδ T cell response to the algae protein, phycoerythrin.

Fri Sep 21 00:00:00 EDT 2012

Autophagy links inflammasomes to atherosclerotic progression.

Cell metabolism

Razani B,Feng C,Coleman T,Emanuel R,Wen H,Hwang S,Ting JP,Virgin HW,Kastan MB,Semenkovich CF

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Wed Apr 04 00:00:00 EDT 2012

Transcription factor RORα is critical for nuocyte development.

Nature immunology

Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN

11-0112 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.

Sun Jan 22 00:00:00 EST 2012

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.

Blood

He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Oct 11 00:00:00 EDT 2012

IKKα-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.

Blood

Balkhi MY,Willette-Brown J,Zhu F,Chen Z,Liu S,Guttridge DC,Karin M,Hu Y

11-0112-41 was used in Flow Cytometry to demonstrate that IKKα regulates B-lineage commitment via combined canonical and noncanonical NF-κB transcriptional activities to target Pax5 expression during hematopoiesis.

Thu Jun 07 00:00:00 EDT 2012

Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.

The Journal of clinical investigation

Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Mon Oct 01 00:00:00 EDT 2012

PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis.

Journal of the American Society of Nephrology : JASN

Ito H,Yan X,Nagata N,Aritake K,Katsumata Y,Matsuhashi T,Nakamura M,Hirai H,Urade Y,Asano K,Kubo M,Utsunomiya Y,Hosoya T,Fukuda K,Sano M

11-0112 was used in Flow cytometry/Cell sorting to explore the contribution of L-PGDS to the development of chronic kidney disease.

Thu Nov 01 00:00:00 EDT 2012

CD73-deficient mice are resistant to carcinogenesis.

Cancer research

Stagg J,Beavis PA,Divisekera U,Liu MC,Möller A,Darcy PK,Smyth MJ

11-0112 was used in Flow cytometry/Cell sorting to investigate the contribution of CD73 to autochthonous tumour formation.

Tue May 01 00:00:00 EDT 2012

Ymer acts as a multifunctional regulator in nuclear factor-κB and Fas signaling pathways.

Molecular medicine (Cambridge, Mass.)

Tsukiyama T,Matsuda-Tsukiyama M,Bohgaki M,Terai S,Tanaka S,Hatakeyama S

11-0112 was used in Flow cytometry/Cell sorting to explore the role of Ymer as a positive or negative regulator in several signalling pathways in mice.

Wed May 09 00:00:00 EDT 2012

Protective role of commensals against Clostridium difficile infection via an IL-1β-mediated positive-feedback loop.

Journal of immunology (Baltimore, Md. : 1950)

Hasegawa M,Kamada N,Jiao Y,Liu MZ,Núñez G,Inohara N

11-0112 was used in Flow cytometry/Cell sorting to reveal a crucial role for translocated commensals in the recruitment of neutrophils to the C. difficile infected intestine.

Sat Sep 15 00:00:00 EDT 2012

Losartan inhibits conventional dendritic cell maturation and Th1 and Th17 polarization responses: Νovel mechanisms of preventive effects on lipopolysaccharide-induced acute lung injury.

International journal of molecular medicine

Liu J,Zhang PS,Yu Q,Liu L,Yang Y,Guo FM,Qiu HB

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that losartan suppresses conventional dendritic cell maturation and Th1 and Th17 polarization responses.

Wed Feb 01 00:00:00 EST 2012

Semaphorin 7a links nerve regeneration and inflammation in the cornea.

Investigative ophthalmology & visual science

Namavari A,Chaudhary S,Ozturk O,Chang JH,Yco L,Sonawane S,Katam N,Khanolkar V,Hallak J,Sarkar J,Jain S

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Mon Jul 09 00:00:00 EDT 2012

Impaired innate immunity in mice deficient in interleukin-1 receptor-associated kinase 4 leads to defective type 1 T cell responses, B cell expansion, and enhanced susceptibility to infection with Toxoplasma gondii.

Infection and immunity

Béla SR,Dutra MS,Mui E,Montpetit A,Oliveira FS,Oliveira SC,Arantes RM,Antonelli LR,McLeod R,Gazzinelli RT

11-0112 was used in Flow cytometry/Cell sorting to investigate the role of IRAK4 in Toxoplasma gondii infection, showing that deficiency leads to impaired innate immunity.

Sat Dec 01 00:00:00 EST 2012

High susceptibility to lipopolysaccharide-induced lethal shock in encephalomyocarditis virus-infected mice.

Scientific reports

Ohtaki H,Ito H,Hoshi M,Osawa Y,Takamatsu M,Hara A,Ishikawa T,Moriwaki H,Saito K,Seishima M

11-0112 was used in Flow cytometry/Cell sorting to examine and explore the effect of lipopolysaccharide on encephalomyocarditis virus-infected mice.

Fri Apr 12 00:00:00 EDT 2013

Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction.

Journal of the American Heart Association

Yan X,Shichita T,Katsumata Y,Matsuhashi T,Ito H,Ito K,Anzai A,Endo J,Tamura Y,Kimura K,Fujita J,Shinmura K,Shen W,Yoshimura A,Fukuda K,Sano M

11-0112 was used in Flow cytometry/Cell sorting to explore potential immune pathways involved in left ventricular remodelling as possible preventative therapeutic options.

Mon Oct 01 00:00:00 EDT 2012

Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB.

Journal of neuroinflammation

Lin S,Liang Y,Zhang J,Bian C,Zhou H,Guo Q,Xiong Y,Li S,Su B

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Fri Feb 24 00:00:00 EST 2012

Induction of histiocytic sarcoma in mouse skeletal muscle.

PloS one

Liu J,Hettmer S,Milsom MD,Hofmann I,Hua F,Miller C,Bronson RT,Wagers AJ

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Thu Feb 07 00:00:00 EST 2013

Preferential expression of integrin αvβ8 promotes generation of regulatory T cells by mouse CD103+ dendritic cells.

Gastroenterology

Païdassi H,Acharya M,Zhang A,Mukhopadhyay S,Kwon M,Chow C,Stuart LM,Savill J,Lacy-Hulbert A

11-0112 was used in Flow cytometry/Cell sorting to investigate the ability of CD103(+) dendritic cells to promote Treg generation through activation of TGF-β by preferential expression of αvβ8.

Tue Nov 01 00:00:00 EDT 2011

A critical role for SOCS3 in innate resistance to Toxoplasma gondii.

Cell host & microbe

Whitmarsh RJ,Gray CM,Gregg B,Christian DA,May MJ,Murray PJ,Hunter CA

11-0112 was used in Flow cytometry/Cell sorting to study the role of SOCS3 in suppressing IL-6 signalling during immune responses to T. gondii infection.

Thu Sep 15 00:00:00 EDT 2011

Virus-induced tumor inflammation facilitates effective DC cancer immunotherapy in a Treg-dependent manner in mice.

The Journal of clinical investigation

Woller N,Knocke S,Mundt B,Gürlevik E,Strüver N,Kloos A,Boozari B,Schache P,Manns MP,Malek NP,Sparwasser T,Zender L,Wirth TC,Kubicka S,Kühnel F

11-0112 was used in Flow cytometry/Cell sorting to highlight viruses as attractive tools for eliciting effective antitumour responses upon DC vaccination.

Fri Jul 01 00:00:00 EDT 2011

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.

The Journal of experimental medicine

Mortensen M,Soilleux EJ,Djordjevic G,Tripp R,Lutteropp M,Sadighi-Akha E,Stranks AJ,Glanville J,Knight S,Jacobsen SE,Kranc KR,Simon AK

11-0112 was used in Flow cytometry/Cell sorting to show that Atg7 is an essential regulator of adult hematopoietic stem cell maintenance.

Mon Mar 14 00:00:00 EDT 2011

CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis.

Cancer research

Stagg J,Divisekera U,Duret H,Sparwasser T,Teng MW,Darcy PK,Smyth MJ

11-0112 was used in Flow cytometry/Cell sorting to study CD73 gene-targeted mice to investigate the role of host-derived CD73 on antitumor immunity and tumor cell metastasis.

Fri Apr 15 00:00:00 EDT 2011

T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis.

PLoS pathogens

Bockstal V,Guirnalda P,Caljon G,Goenka R,Telfer JC,Frenkel D,Radwanska M,Magez S,Black SJ

11-0112 was used in Flow cytometry/Cell sorting to study how infection-induced deletion of transitional B cells prevents replenishment of mature B cell compartments during T. brucei infection.

Wed Jun 01 00:00:00 EDT 2011

Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages.

Immunology

Buhtoiarov IN,Sondel PM,Wigginton JM,Buhtoiarova TN,Yanke EM,Mahvi DA,Rakhmilevich AL

11-0112 was used in Flow cytometry/Cell sorting to show that chemotherapy and anti-CD40 + CpG-ODN IT synergise in the induction of anti-tumour effects which are associated with the phenotypic repolarisation of tumour-associated Mφ.

Tue Feb 01 00:00:00 EST 2011

CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism.

Journal of immunology (Baltimore, Md. : 1950)

Landrigan A,Wong MT,Utz PJ

11-0112 was used in Flow cytometry/Cell sorting to study the ability of oligodeoxynucleotides to activate and polarise T cells.

Thu Sep 15 00:00:00 EDT 2011

Nucleotide-binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen.

Journal of immunology (Baltimore, Md. : 1950)

Hasegawa M,Yamazaki T,Kamada N,Tawaratsumida K,Kim YG,Núñez G,Inohara N

11-0112 was used in Flow cytometry/Cell sorting to investigate how Nod1 regulates host susceptibility to C. difficile, and how Nod1-mediated neutrophil recruitment may be an important immune response against the pathogen.

Fri Apr 15 00:00:00 EDT 2011

The actin-bundling protein L-plastin is essential for marginal zone B cell development.

Journal of immunology (Baltimore, Md. : 1950)

Todd EM,Deady LE,Morley SC

11-0112 was used in Flow cytometry/Cell sorting to study the role of the actin-bundling protein L-plastin in B cell chemotaxis.

Thu Sep 15 00:00:00 EDT 2011

Identification of a novel antigen cross-presenting cell type in spleen.

Journal of cellular and molecular medicine

Tan JK,Quah BJ,Griffiths KL,Periasamy P,Hey YY,O'Neill HC

11-0112 was used in Flow cytometry/Cell sorting to study a novel DC type produced by in vitro haematopoiesis which has distinct antigen-presenting potential and reflects a DC subset present also in vivo in spleen.

Sun May 01 00:00:00 EDT 2011

IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid.

International immunology

Yabu M,Shime H,Hara H,Saito T,Matsumoto M,Seya T,Akazawa T,Inoue N

11-0112 was used in Immunofluorescence to show lactic acid functions as an inflammatory mediator that activates IL-23-dependent and -independent pathways to promote chronic inflammation in tumour microenvironments.

Sat Jan 01 00:00:00 EST 2011

PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.

PloS one

Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Tue Nov 15 00:00:00 EST 2011

Dectin-1 mediates in vitro phagocytosis of Candida albicans yeast cells by retinal microglia.

FEMS immunology and medical microbiology

Maneu V,Yáñez A,Murciano C,Molina A,Gil ML,Gozalbo D

11-0112 was used in Flow cytometry/Cell sorting to investigate the expression of TLR2 and Dectin-1 in retinal microglia and their involvement in Candida albicans phagocytosis.

Sat Oct 01 00:00:00 EDT 2011

Candida albicans induces selective development of macrophages and monocyte derived dendritic cells by a TLR2 dependent signalling.

PloS one

Yáñez A,Megías J,O'Connor JE,Gozalbo D,Gil ML

11-0112 was used in Flow cytometry/Cell sorting to investigate how C. albicans invasive infection with a low virulence strain results in a rapid expansion of HSPCs.

Tue Feb 28 00:00:00 EST 2012

Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization.

PloS one

Edelson BT,Bradstreet TR,KC W,Hildner K,Herzog JW,Sim J,Russell JH,Murphy TL,Unanue ER,Murphy KM

11-0112 was used in Flow cytometry/Cell sorting to compare development of peripheral tissue dendritic cells, and susceptibility to experimental autoimmune encephalitis in GM-CSF receptor deficient mice.

Thu Mar 15 00:00:00 EDT 2012

Acute Disruption of Bone Marrow B Lymphopoiesis and Apoptosis of Transitional and Marginal Zone B Cells in the Spleen following a Blood-Stage Plasmodium chabaudi Infection in Mice.

Journal of parasitology research

Bockstal V,Geurts N,Magez S

11-0112 was used in Flow cytometry/Cell sorting to investigate the effects of a blood-stage Plasmodium chabaudi infection in the spleen and bone marrow of mice.

Thu Jul 14 00:00:00 EDT 2011

Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol.

PloS one

Hegde VL,Nagarkatti PS,Nagarkatti M

11-0112 was used in Flow cytometry/Cell sorting to ameliorate experimental autoimmune hepatitis following activation of TRPV1 receptors in myeloid-derived suppressor cells by cannabidiol.

Fri Apr 01 00:00:00 EDT 2011

Neuroprotection in a rabbit model of intraventricular haemorrhage by cyclooxygenase-2, prostanoid receptor-1 or tumour necrosis factor-alpha inhibition.

Brain : a journal of neurology

Vinukonda G,Csiszar A,Hu F,Dummula K,Pandey NK,Zia MT,Ferreri NR,Ungvari Z,LaGamma EF,Ballabh P

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Sun Aug 01 00:00:00 EDT 2010

Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis.

Proceedings of the National Academy of Sciences of the United States of America

Stagg J,Divisekera U,McLaughlin N,Sharkey J,Pommey S,Denoyer D,Dwyer KM,Smyth MJ

11-0112 was used in Flow cytometry/Cell sorting to investigate the therapeutic potential and mechanism of action of mAb-based therapy against CD73.

Tue Jan 26 00:00:00 EST 2010

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice.

Proceedings of the National Academy of Sciences of the United States of America

Rodriguez-Manzanet R,Sanjuan MA,Wu HY,Quintana FJ,Xiao S,Anderson AC,Weiner HL,Green DR,Kuchroo VK

11-0112 was used in Flow cytometry/Cell sorting to investigate the significance of interactions between TIM-4 and phophatidylserine, showing that TIM-4 deficiency leads to T and B cell hyperactivity and autoimmunity.

Tue May 11 00:00:00 EDT 2010

The death effector domain protein PEA-15 negatively regulates T-cell receptor signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Pastorino S,Renganathan H,Caliva MJ,Filbert EL,Opoku-Ansah J,Sulzmaier FJ,Gawecka JE,Werlen G,Shaw AS,Ramos JW

11-0112 was used in Flow cytometry/Cell sorting to investigate the physiological function of PEA-15, showing that it negatively regulates T-cell receptor signalling.

Sun Aug 01 00:00:00 EDT 2010

IL-1-induced inflammation promotes development of leishmaniasis in susceptible BALB/c mice.

International immunology

Voronov E,Dotan S,Gayvoronsky L,White RM,Cohen I,Krelin Y,Benchetrit F,Elkabets M,Huszar M,El-On J,Apte RN

11-0112 was used in Flow cytometry/Cell sorting to assess the role of host derived IL-1 on the course of Leishmania major infection in susceptible BLAB/c mice.

Thu Apr 01 00:00:00 EDT 2010

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.

Cell stem cell

Somervaille TC,Matheny CJ,Spencer GJ,Iwasaki M,Rinn JL,Witten DM,Chang HY,Shurtleff SA,Downing JR,Cleary ML

11-0112 was used in Flow cytometry/Cell sorting to link the frequency of aberrantly self-renewing progenitor-like cancer stem cells (CSCs) to prognosis in human cancer, namely myeloid leukemia.

Fri Feb 06 00:00:00 EST 2009

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.

Cell stem cell

Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Jun 05 00:00:00 EDT 2009

An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice.

The Journal of clinical investigation

Tieu BC,Lee C,Sun H,Lejeune W,Recinos A,Ju X,Spratt H,Guo DC,Milewicz D,Tilton RG,Brasier AR

11-0112 was used in Flow cytometry/Cell sorting to identify a vascular inflammatory pathway that contributes to the development of cardiovascular disease.

Tue Dec 01 00:00:00 EST 2009

The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies.

Cancer research

Ozao-Choy J,Ma G,Kao J,Wang GX,Meseck M,Sung M,Schwartz M,Divino CM,Pan PY,Chen SH

11-0112 was used in Flow cytometry/Cell sorting to suggest that sunitinib can be used to reverse immune suppression and as a potentially useful adjunct for enhancing the efficacy of immune-based cancer therapy for advanced malignancies.

Sun Mar 15 00:00:00 EDT 2009

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice.

Diabetes

Parker MJ,Xue S,Alexander JJ,Wasserfall CH,Campbell-Thompson ML,Battaglia M,Gregori S,Mathews CE,Song S,Troutt M,Eisenbeis S,Williams J,Schatz DA,Haller MJ,Atkinson MA

11-0112 was used in Flow cytometry/Cell sorting to investigate the use of ATG and GCSF in therapies to reverse overt hyperglycaemia in a diabetic mouse model.

Thu Oct 01 00:00:00 EDT 2009

Involvement of IQGAP3, a regulator of Ras/ERK-related cascade, in hepatocyte proliferation in mouse liver regeneration and development.

Journal of cellular physiology

Kunimoto K,Nojima H,Yamazaki Y,Yoshikawa T,Okanoue T,Tsukita S

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunofluorescence

Tue Sep 01 00:00:00 EDT 2009

Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-gamma and counteraction by interferon-gamma.

Arthritis research & therapy

Kelchtermans H,Schurgers E,Geboes L,Mitera T,Van Damme J,Van Snick J,Uyttenhove C,Matthys P

11-0112 was used in Flow cytometry/Cell sorting to analyse the mechanisms of action of IL-17 in arthritis and the effect of IFN-gamma on those mechanisms.

Wed Dec 16 00:00:00 EST 2009

Naive mouse macrophages become activated following recognition of L5178Y lymphoma cells via concurrent ligation of CD40, NKG2D, and CD18 molecules.

Journal of immunology (Baltimore, Md. : 1950)

Buhtoiarov IN,Rakhmilevich AL,Lanier LL,Ranheim EA,Sondel PM

11-0112 was used in Flow cytometry/Cell sorting to investigate the mechanisms of tumour-macrophage interactions leading to macrophage activation, showing that activation follows ligation of CD40, NKG2D, and CD18 molecules.

Sun Feb 15 00:00:00 EST 2009

c-Myb is required for pro-B cell differentiation.

Journal of immunology (Baltimore, Md. : 1950)

Fahl SP,Crittenden RB,Allman D,Bender TP

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that c-Myb is absolutely required for the survival and differentiation of CD19(+) B-lineage cells.

Sun Nov 01 00:00:00 EDT 2009

Hypercostimulation through 4-1BB distorts homeostasis of immune cells.

Journal of immunology (Baltimore, Md. : 1950)

Lee SW,Salek-Ardakani S,Mittler RS,Croft M

11-0112 was used in Flow cytometry/Cell sorting to investigate the potential side effects of immunotherapeutic strategies using Abs against costimulatory molecules.

Mon Jun 01 00:00:00 EDT 2009

Critical role of the interleukin-17/interleukin-17 receptor axis in regulating host susceptibility to respiratory infection with Chlamydia species.

Infection and immunity

Zhou X,Chen Q,Moore J,Kolls JK,Halperin S,Wang J

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that Chlamydia stimulates IL-17/IL-17R-associated responses in Chlamydia-resistant and Chlamydia-susceptible mice.

Sun Nov 01 00:00:00 EDT 2009

Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.

BMC biotechnology

Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Immunohistochemistry

Wed Jan 07 00:00:00 EST 2009

DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors.

The Journal of experimental medicine

Gilfillan S,Chan CJ,Cella M,Haynes NM,Rapaport AS,Boles KS,Andrews DM,Smyth MJ,Colonna M

11-0112 was used in Flow cytometry/Cell sorting to study the promoted activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors by dnam-1.

Mon Dec 22 00:00:00 EST 2008

CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury.

The American journal of pathology

Li G,Sanders JM,Bevard MH,Sun Z,Chumley JW,Galkina EV,Ley K,Sarembock IJ

11-0112 was used in Flow cytometry/Cell sorting to study the function of CD40 ligand in neointima formation following vascular injury in an atherogenic animal model.

Tue Apr 01 00:00:00 EDT 2008

Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.

Journal of immunology (Baltimore, Md. : 1950)

Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR

11-0112 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.

Sat Nov 15 00:00:00 EST 2008

Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.

Journal of immunology (Baltimore, Md. : 1950)

Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR

11-0112 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.

Sat Nov 15 00:00:00 EST 2008

Runx proteins are involved in regulation of CD122, Ly49 family and IFN-gamma expression during NK cell differentiation.

International immunology

Ohno S,Sato T,Kohu K,Takeda K,Okumura K,Satake M,Habu S

11-0112 was used in Flow cytometry/Cell sorting to investigate the role of Runx family proteins in NK cells, showing that they are involved in regulation of CD122, Ly49 family and IFN-gamma expression during differentiation.

Tue Jan 01 00:00:00 EST 2008

Analysis of the IKKbeta/NF-kappaB signaling pathway during embryonic angiogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists

Hou Y,Li F,Karin M,Ostrowski MC

11-0112 was used in Flow cytometry/Cell sorting to describe the IKKβ/NF-κB signalling pathway involved in embryonic angiogenesis, which Ikkβ locus disruption in foetal liver vasculature revealed to be responsible for regulation of hepatocyte proliferation and apoptosis, however not for hematopoiesis.

Wed Oct 01 00:00:00 EDT 2008

VEGF-C, a lymphatic growth factor, is a RANKL target gene in osteoclasts that enhances osteoclastic bone resorption through an autocrine mechanism.

The Journal of biological chemistry

Zhang Q,Guo R,Lu Y,Zhao L,Zhou Q,Schwarz EM,Huang J,Chen D,Jin ZG,Boyce BF,Xing L

11-0112 was used in Immunofluorescence-cell culture cells to investigate whether osteoclasts secrete the lymphatic growth factor, VEGF-C, to increase their resorptive activity.

Fri May 09 00:00:00 EDT 2008

Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.

The Journal of biological chemistry

Chen Y,Wang X,Di L,Fu G,Chen Y,Bai L,Liu J,Feng X,McDonald JM,Michalek S,He Y,Yu M,Fu YX,Wen R,Wu H,Wang D

Published figure using CD11b monoclonal antibody (Product # 11-0112-41) in Flow Cytometry

Fri Oct 24 00:00:00 EDT 2008

Disruption of CXCR4 enhances osteoclastogenesis and tumor growth in bone.

Proceedings of the National Academy of Sciences of the United States of America

Hirbe AC,Rubin J,Uluçkan O,Morgan EA,Eagleton MC,Prior JL,Piwnica-Worms D,Weilbaecher KN

11-0112 was used in Flow cytometry/Cell sorting to demonstrate that disruption of CXCR4 enhances osteoclastogenesis and suggest that inhibition of CXCR4 may enhance skeletal tumour burden.

Tue Aug 28 00:00:00 EDT 2007

Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk.

Blood

Takizawa H,Kubo-Akashi C,Nobuhisa I,Kwon SM,Iseki M,Taga T,Takatsu K,Takaki S

11-0112 was used in Flow cytometry/Cell sorting to investigate the potential of Lnk for augmented engraftment of HSCs.

Sat Apr 01 00:00:00 EST 2006

Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth.

Proceedings of the National Academy of Sciences of the United States of America

Kikuchi K,Kondo M

11-0112 was used in Flow cytometry/Cell sorting to demonstrate how foetal haematopoietic stem cells may acquire adult characteristics between 1 and 2 weeks after birth in mouse bone marrow.

Tue Nov 21 00:00:00 EST 2006

Increased expression of germinal center-associated nuclear protein RNA-primase is associated with lymphomagenesis.

Cancer research

Fujimura S,Xing Y,Takeya M,Yamashita Y,Ohshima K,Kuwahara K,Sakaguchi N

11-0112 was used in Flow cytometry/Cell sorting to study the role of GANP in lymphomagenesis.

Fri Jul 01 00:00:00 EDT 2005

Estrogen stimulates microglia and brain recovery from hypoxia-ischemia in normoglycemic but not diabetic female mice.

The Journal of clinical investigation

Zhang L,Nair A,Krady K,Corpe C,Bonneau RH,Simpson IA,Vannucci SJ

11-0112 was used in Flow cytometry/Cell sorting to describe antiapoptotic gene expression (bfl-1) in the brain with localization to microglia and macrophages.

Thu Jan 01 00:00:00 EST 2004

Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes.

The Journal of experimental medicine

Auerbuch V,Brockstedt DG,Meyer-Morse N,O'Riordan M,Portnoy DA

11-0112 was used in Flow cytometry/Cell sorting to investigate the role of type I interferon receptors in viral defense using Listeria monocytogenes infection of mice as a model.

Mon Aug 16 00:00:00 EDT 2004

生物信息学

蛋白别名: CD11 antigen-like family member B; CD11B (p170); cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; CR-3 alpha chain; integrin alpha-M; leukocyte adhesion receptor MO1; Mac-1 alpha; Mac-1 alpha (Mac1A); macrophage antigen alpha; MGC117044

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基因别名: Cd11b; CD11b/CD18; CR3; CR3A; F730045J24Rik; Ly-40; Mac-1; Mac-1a; MAC1

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Entrez Gene ID: (Mouse) 16409

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功能

opsonin binding glycoprotein binding heparin binding heparan sulfate proteoglycan binding metal ion binding protein heterodimerization activity integrin

参与通路

leukocyte migration involved in inflammatory response cell adhesion leukocyte cell-cell adhesion integrin-mediated signaling pathway microglia development single organismal cell-cell adhesion neutrophil chemotaxis cellular extravasation activated T cell proliferation

CD11b Monoclonal Antibody (M1/70), FITC, eBioscience™

CD11b Antibody (11-0112-41) in Flow

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11-0112-41

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