Product References
TLR4 is one of the receptors for Chikungunya virus envelope protein E2 and regulates virus induced pro-inflammatory responses in host macrophages.
Frontiers in immunology
Mahish C,De S,Chatterjee S,Ghosh S,Keshry SS,Mukherjee T,Khamaru S,Tung KS,Subudhi BB,Chattopadhyay S,Chattopadhyay S
17-0862-82 was used in Flow cytometry/Cell sorting to report TLR4 as one of the novel receptors to facilitate the attachment and entry of CHIKV in host macrophages, the TLR4-CHIKV-E2 interactions are essential for efficient viral entry and modulation of infection-induced pro-inflammatory responses in host macrophages, which might have translational implication for designing future therapeutics to regulate the CHIKV infection.
Thu May 18 00:00:00 EDT 2023
TLR4 is one of the receptors for Chikungunya virus envelope protein E2 and regulates virus induced pro-inflammatory responses in host macrophages.
Frontiers in immunology
Mahish C,De S,Chatterjee S,Ghosh S,Keshry SS,Mukherjee T,Khamaru S,Tung KS,Subudhi BB,Chattopadhyay S,Chattopadhyay S
17-0862-82 was used in Flow cytometry/Cell sorting to report TLR4 as one of the novel receptors to facilitate the attachment and entry of CHIKV in host macrophages, the TLR4-CHIKV-E2 interactions are essential for efficient viral entry and modulation of infection-induced pro-inflammatory responses in host macrophages, which might have translational implication for designing future therapeutics to regulate the CHIKV infection.
Thu May 18 00:00:00 EDT 2023
Carvacrol protects mice against LPS-induced sepsis and attenuates inflammatory response in macrophages by modulating the ERK1/2 pathway.
Scientific reports
Yan C,Kuang W,Jin L,Wang R,Niu L,Xie C,Ding J,Liao Y,Wang L,Wan H,Ma G
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Aug 07 00:00:00 EDT 2023
TREM2 expression promotes liver and peritoneal M2 macrophage polarization in mice infected with Schistosoma japonicum.
Journal of cellular and molecular medicine
Zhu D,Huang M,Shen P,Zhang B,Chen G,Chen J,Duan L,Duan Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Aug 01 00:00:00 EDT 2023
A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance.
Bioactive materials
Li W,Yan J,Tian H,Li B,Wang G,Sang W,Zhang Z,Zhang X,Dai Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
BushenHuoxue decoction suppresses M1 macrophage polarization and prevents LPS induced inflammatory bone loss by activating AMPK pathway.
Heliyon
Chen S,Tao L,Zhu F,Wang Z,Zhuang Q,Li Y,Yang Y,Feng C,Shi H,Shi J,Zhu L,Xiao L,Geng D,Wang Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
CD8α+ dendritic cells potentiate antitumor and immune activities against murine ovarian cancers.
Scientific reports
Lee SW,Lee H,Lee KW,Kim MJ,Kang SW,Lee YJ,Kim H,Kim YM
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Jan 03 00:00:00 EST 2023
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Immunity, inflammation and disease
Tan H,Cao L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Alpha-ketoglutarate promotes alveolar bone regeneration by modulating M2 macrophage polarization.
Bone reports
Li Y,Liu L,Li Y,Song W,Shao B,Li H,Lin W,Li Q,Shuai X,Bai M,Zhao B,Guo Y,Yuan Q,Wang Y
17-0862-82 was used in Flow cytometry/Cell sorting to investigate the effect of Alpha-ketoglutarate (αKG) on alveolar socket healing and reveal the underlying mechanism in the view of macrophage polarization.
Thu Jun 01 00:00:00 EDT 2023
Exosomal Lnc NEAT1 from endothelial cells promote bone regeneration by regulating macrophage polarization via DDX3X/NLRP3 axis.
Journal of nanobiotechnology
Chen Y,Wu Y,Guo L,Yuan S,Sun J,Zhao K,Wang J,An R
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Mar 20 00:00:00 EDT 2023
FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.
Life science alliance
Kulkarni R,Kasani SK,Tsai CY,Tung SY,Yeh KH,Yu CA,Chang W
17-0862-82 was used in Flow cytometry/Cell sorting to highlight the importance of FAM21-TLR2/CLEC4E axis in a host immune response against the lethal C. albicans infection.
Sat Apr 01 00:00:00 EDT 2023
Role of low-intensity pulsed ultrasound in regulating macrophage polarization to accelerate tendon-bone interface repair.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Xu Z,Li S,Wan L,Hu J,Lu H,Zhang T
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
BMP-2 functional polypeptides relieve osteolysis via bi-regulating bone formation and resorption coupled with macrophage polarization.
NPJ Regenerative medicine
Wang J,Xue Y,Wang Y,Liu C,Hu S,Zhao H,Gu Q,Yang H,Huang L,Zhou X,Shi Q
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Feb 09 00:00:00 EST 2023
Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.
Materials today. Bio
Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sat Apr 01 00:00:00 EDT 2023
Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model.
Acta pharmaceutica Sinica. B
Zhang L,Zhu Y,Wei X,Chen X,Li Y,Zhu Y,Xia J,Huang Y,Huang Y,Wang J,Pang Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Aug 01 00:00:00 EDT 2022
Enhanced uptake and anti-maturation effect of celastrol-loaded mannosylated liposomes on dendritic cells for psoriasis treatment.
Acta pharmaceutica Sinica. B
Xi L,Lin Z,Qiu F,Chen S,Li P,Chen X,Wang Z,Zheng Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2022
Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype.
Molecular therapy. Nucleic acids
De Santi C,Nally FK,Afzal R,Duffy CP,Fitzsimons S,Annett SL,Robson T,Dowling JK,Cryan SA,McCoy CE
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Sep 13 00:00:00 EDT 2022
Oncolytic Zika virus promotes intratumoral T cell infiltration and improves immunotherapy efficacy in glioblastoma.
Molecular therapy oncolytics
Chen L,Zhou C,Chen Q,Shang J,Liu Z,Guo Y,Li C,Wang H,Ye Q,Li X,Zu S,Li F,Xia Q,Zhou T,Li A,Wang C,Chen Y,Wu A,Qin C,Man J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Mar 17 00:00:00 EDT 2022
G9a promotes inflammation in Streptococcus pneumoniae induced pneumonia mice by stimulating M1 macrophage polarization and H3K9me2 methylation in FOXP1 promoter region.
Annals of translational medicine
Li Y,Li G,Zhang L,Li Y,Zhao Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model.
Frontiers in immunology
Jiang W,Wang X,Su Y,Cai L,Li J,Liang J,Gu Q,Sun M,Shi L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue May 03 00:00:00 EDT 2022
Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain.
eLife
Kovacs MA,Cowan MN,Babcock IW,Sibley LA,Still K,Batista SJ,Labuzan SA,Sethi I,Harris TH
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Dec 21 00:00:00 EST 2022
MicroRNA-382 Promotes M2-Like Macrophage via the SIRP-α/STAT3 Signaling Pathway in Aristolochic Acid-Induced Renal Fibrosis.
Frontiers in immunology
Wang X,Jia P,Ren T,Zou Z,Xu S,Zhang Y,Shi Y,Bao S,Li Y,Fang Y,Ding X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri May 20 00:00:00 EDT 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Chromomycin A5 induces bona fide immunogenic cell death in melanoma.
Frontiers in immunology
Florêncio KGD,Edson EA,Fernandes KSDS,Luiz JPM,Pinto FDCL,Pessoa ODL,Cunha FQ,Machado-Neto JA,Wilke DV
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Nov 29 00:00:00 EST 2022
In situ generation of micrometer-sized tumor cell-derived vesicles as autologous cancer vaccines for boosting systemic immune responses.
Nature communications
Guo Y,Wang SZ,Zhang X,Jia HR,Zhu YX,Zhang X,Gao G,Jiang YW,Li C,Chen X,Wu SY,Liu Y,Wu FG
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Nov 01 00:00:00 EDT 2022
Targeting dendritic cells with TLR-2 ligand-coated nanoparticles loaded with Mycobacterium tuberculosis epitope induce antituberculosis immunity.
The Journal of biological chemistry
Kumar Das D,Zafar MA,Nanda S,Singh S,Lamba T,Bashir H,Singh P,Maurya SK,Nadeem S,Sehrawat S,Bhalla V,Agrewala JN
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2022
Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling.
Molecular cancer
Rizzello C,Cancila V,Sangaletti S,Botti L,Ratti C,Milani M,Dugo M,Bertoni F,Tripodo C,Chiodoni C,Colombo MP
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Dec 12 00:00:00 EST 2022
Dental pulp stem cell-derived exosomes suppress M1 macrophage polarization through the ROS-MAPK-NFκB P65 signaling pathway after spinal cord injury.
Journal of nanobiotechnology
Liu C,Hu F,Jiao G,Guo Y,Zhou P,Zhang Y,Zhang Z,Yi J,You Y,Li Z,Wang H,Zhang X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Feb 02 00:00:00 EST 2022
Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.
Theranostics
Mao Q,Min J,Zeng R,Liu H,Li H,Zhang C,Zheng A,Lin J,Liu X,Wu M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Sep 29 00:00:00 EDT 2022
Role of circular RNA cdr1as in modulation of macrophage phenotype.
Life sciences
Gonzalez C,Cimini M,Cheng Z,Benedict C,Wang C,Trungcao M,Mallaredy V,Rajan S,Garikipati VNS,Kishore R
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Nov 15 00:00:00 EST 2022
Precise delivery of doxorubicin and imiquimod through pH-responsive tumor microenvironment-active targeting micelles for chemo- and immunotherapy.
Materials today. Bio
Wen YH,Hsieh PI,Chiu HC,Chiang CW,Lo CL,Chiang YT
17-0862-82 was used in Flow cytometry/Cell sorting to show that these micelles exhibit precise pH responsiveness and ideal drug delivery capabilities for combined chemo- and immunotherapy; these results significantly contribute to the future development of nanomedicines in cancer therapy.
Thu Dec 15 00:00:00 EST 2022
A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis.
Biomaterials
Keum H,Kim D,Kim J,Kim TW,Whang CH,Jung W,Jon S
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sun Aug 01 00:00:00 EDT 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages.
Immune network
Sim H,Jeong D,Kim HI,Pak S,Thapa B,Kwon HJ,Lee K
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Pseudomonas aeruginosa PcrV Enhances the Nitric Oxide-Mediated Tumoricidal Activity of Tumor-Associated Macrophages via a TLR4/PI3K/AKT/mTOR-Glycolysis-Nitric Oxide Circuit.
Frontiers in oncology
Yu H,Bai Y,Qiu J,He X,Xiong J,Dai Q,Wang X,Li Y,Sheng H,Xin R,Jiang L,Li Q,Li D,Zhang H,Zhang L,Chen Q,Peng J,Hu X,Zhang K
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Dec 15 00:00:00 EST 2021
Prostaglandin E2 serves a dual role in regulating the migration of dendritic cells.
International journal of molecular medicine
Diao G,Huang J,Zheng X,Sun X,Tian M,Han J,Guo J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Exosomes derived from inflammatory myoblasts promote M1 polarization and break the balance of myoblast proliferation/differentiation.
World journal of stem cells
Luo ZW,Sun YY,Lin JR,Qi BJ,Chen JW
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri Nov 26 00:00:00 EST 2021
Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat-treated tumor cell lysates enhance antitumor activity in murine lung cancer.
Oncology letters
Chen H,Tan J,Li X,Li H,Wu W,Wu Y,Zhang J,Gu L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.
Cells
Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Nov 15 00:00:00 EST 2021
Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity.
Journal for immunotherapy of cancer
Wang Z,Xu F,Hu J,Zhang H,Cui L,Lu W,He W,Wang X,Li M,Zhang H,Xiong W,Xie C,Liu Y,Zhou P,Liu J,Huang P,Qin XF,Xia X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sat May 01 00:00:00 EDT 2021
A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge.
Cell reports
Jiang W,Shi L,Cai L,Wang X,Li J,Li H,Liang J,Gu Q,Ji G,Li J,Liu L,Sun M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Dec 14 00:00:00 EST 2021
Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis.
Nature communications
Li H,Wang M,Huang B,Zhu SW,Zhou JJ,Chen DR,Cui R,Zhang M,Sun ZJ
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Dec 09 00:00:00 EST 2021
Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy.
Journal of neuroinflammation
Oladiran O,Shi XQ,Yang M,Fournier S,Zhang J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Mar 22 00:00:00 EDT 2021
Adrenomedullin 2 improves bone regeneration in type 1 diabetic rats by restoring imbalanced macrophage polarization and impaired osteogenesis.
Stem cell research & therapy
Wang F,Kong L,Wang W,Shi L,Wang M,Chai Y,Xu J,Kang Q
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu May 13 00:00:00 EDT 2021
Marine-inspired molecular mimicry generates a drug-free, but immunogenic hydrogel adhesive protecting surgical anastomosis.
Bioactive materials
Huang J,Jiang Y,Liu Y,Ren Y,Xu Z,Li Z,Zhao Y,Wu X,Ren J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Feb 10 00:00:00 EST 2022
C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune Encephalomyelitis.
Frontiers in immunology
Shen ZY,Zheng Y,Pecsok MK,Wang K,Li W,Gong MJ,Wu F,Zhang L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Jul 01 00:00:00 EDT 2021
MiR-19a-3p Suppresses M1 Macrophage Polarization by Inhibiting STAT1/IRF1 Pathway.
Frontiers in pharmacology
Zhu X,Guo Q,Zou J,Wang B,Zhang Z,Wei R,Zhao L,Zhang Y,Chu C,Fu X,Li X
17-0862 was used in Flow cytometry/Cell sorting to confirm that miR-19a-3p, as a direct regulator of STAT1, inhibited M1 macrophages polarization.
Sun May 23 00:00:00 EDT 2021
Cryomicroneedles for transdermal cell delivery.
Nature biomedical engineering
Chang H,Chew SWT,Zheng M,Lio DCS,Wiraja C,Mei Y,Ning X,Cui M,Than A,Shi P,Wang D,Pu K,Chen P,Liu H,Xu C
17-0862-82 was used in Flow Cytometry to report the design and proof-of-concept application of cryogenic microneedle patches for the transdermal delivery of living cells.
Wed Sep 01 00:00:00 EDT 2021
PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway.
Frontiers in immunology
Lv N,Jin S,Liang Z,Wu X,Kang Y,Su L,Dong Y,Wang B,Ma T,Shi L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Feb 28 00:00:00 EST 2022
Podocytes present antigen to activate specific T cell immune responses in inflammatory renal disease.
The Journal of pathology
Li S,Liu Y,He Y,Rong W,Zhang M,Li L,Liu Z,Zen K
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Brief exposure to hyperglycemia activates dendritic cells in vitro and in vivo.
Journal of cellular physiology
Thomas AM,Dong Y,Beskid NM,García AJ,Adams AB,Babensee JE
17-0862-82 was used in Flow Cytometry to show that expression of the costimulatory molecule CD86 was found to reliably increase when dendritic cells were exposed to hyperglycemia.
Mon Jun 01 00:00:00 EDT 2020
E6‑regulated overproduction of prostaglandin E2 may inhibit migration of dendritic cells in human papillomavirus 16‑positive cervical lesions.
International journal of oncology
Huang J,Diao G,Zhang Q,Chen Y,Han J,Guo J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Mesenchymal stem cell-secreted extracellular vesicles carrying TGF-β1 up-regulate miR-132 and promote mouse M2 macrophage polarization.
Journal of cellular and molecular medicine
Wang Y,Han B,Wang Y,Wang C,Zhang H,Xue J,Wang X,Niu T,Niu Z,Chen Y
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Interleukin-9 Inhibits Lung Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages.
Molecules and cells
Park SM,Do-Thi VA,Lee JO,Lee H,Kim YS
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sun May 31 00:00:00 EDT 2020
Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model.
Molecular medicine reports
Li G,Yang L,Li D,Zhang J,Du L,Xia L,Liu Y,Hu W
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2020
Angiotensin II induces RAW264.7 macrophage polarization to the M1‑type through the connexin 43/NF‑κB pathway.
Molecular medicine reports
Wu L,Chen K,Xiao J,Xin J,Zhang L,Li X,Li L,Si J,Wang L,Ma K
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri May 01 00:00:00 EDT 2020
Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity.
Journal for immunotherapy of cancer
Efimova I,Catanzaro E,Van der Meeren L,Turubanova VD,Hammad H,Mishchenko TA,Vedunova MV,Fimognari C,Bachert C,Coppieters F,Lefever S,Skirtach AG,Krysko O,Krysko DV
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sun Nov 01 00:00:00 EDT 2020
Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade.
Cell death & disease
Liu Y,Cai J,Liu W,Lin Y,Guo L,Liu X,Qin Z,Xu C,Zhang Y,Su X,Deng K,Yan G,Liang J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sat Dec 12 00:00:00 EST 2020
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
17-0862 was used in Flow cytometry/Cell sorting to prove decreased miR-103 is involved in RSA by increasing M1 macrophage polarization via promoting STAT1/IRF1 signaling pathway. miR-103 may be explored as a promising diagnostic marker and therapeutic target for RSA.
Fri Nov 12 00:00:00 EST 2021
MiR-103 protects from recurrent spontaneous abortion via inhibiting STAT1 mediated M1 macrophage polarization.
International journal of biological sciences
Zhu X,Liu H,Zhang Z,Wei R,Zhou X,Wang Z,Zhao L,Guo Q,Zhang Y,Chu C,Wang L,Li X
17-0862 was used in Flow cytometry/Cell sorting to prove decreased miR-103 is involved in RSA by increasing M1 macrophage polarization via promoting STAT1/IRF1 signaling pathway. miR-103 may be explored as a promising diagnostic marker and therapeutic target for RSA.
Fri Nov 12 00:00:00 EST 2021
Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma.
Cancers
Trempolec N,Doix B,Degavre C,Brusa D,Bouzin C,Riant O,Feron O
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Feb 27 00:00:00 EST 2020
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.
Nature communications
Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Aug 27 00:00:00 EDT 2020
Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy.
Biomedicines
Ebelt ND,Zuniga E,Marzagalli M,Zamloot V,Blazar BR,Salgia R,Manuel ER
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Dec 16 00:00:00 EST 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Mar 24 00:00:00 EDT 2020
Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.
International journal of molecular sciences
Yoon CH,Ryu JS,Hwang HS,Kim MK
17-0862 was used in Flow cytometry/Cell sorting to suggest that age-dependent DED in C57BL/6 mice is related to inflammation of the LGs, the development of MG atrophy, and oxidative stress in both glands.
Thu Jun 11 00:00:00 EDT 2020
Mesenchymal stromal cells induce distinct myeloid-derived suppressor cells in inflammation.
JCI insight
Lee HJ,Ko JH,Kim HJ,Jeong HJ,Oh JY
17-0862 was used in Flow cytometry/Cell sorting to reveal that suppression of prostaglandin E2 (PGE2) and HGF secretion in MSCs by siRNA transfection partially reversed the effects of MSCs on MDSC differentiation.
Thu Jun 18 00:00:00 EDT 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Jun 29 00:00:00 EDT 2020
Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses.
Cell reports
Blagih J,Zani F,Chakravarty P,Hennequart M,Pilley S,Hobor S,Hock AK,Walton JB,Morton JP,Gronroos E,Mason S,Yang M,McNeish I,Swanton C,Blyth K,Vousden KH
17-0862 was used in Flow cytometry/Cell sorting to show suppressive regulatory T cells accumulate in tumour cells in the absence of p53 indicating a pathway in which cancer cells circumvent immune destruction.
Tue Jan 14 00:00:00 EST 2020
Polyanhydride Nanoparticles Induce Low Inflammatory Dendritic Cell Activation Resulting in CD8+ T Cell Memory and Delayed Tumor Progression.
International journal of nanomedicine
Darling R,Senapati S,Christiansen J,Liu L,Ramer-Tait AE,Narasimhan B,Wannemuehler M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Dec 07 00:00:00 EST 2020
Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity.
Cell
Brown CC,Gudjonson H,Pritykin Y,Deep D,Lavallée VP,Mendoza A,Fromme R,Mazutis L,Ariyan C,Leslie C,Pe'er D,Rudensky AY
17-0862 was used in Flow cytometry/Cell sorting to identify two principal cDC2 lineages defined by distinct developmental pathways and transcriptional regulators, including T-bet and RORγt, two key transcription factors known to define innate and adaptive lymphocyte subsets.
Thu Oct 31 00:00:00 EDT 2019
cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
The Journal of clinical investigation
Wang Z,Chen J,Hu J,Zhang H,Xu F,He W,Wang X,Li M,Lu W,Zeng G,Zhou P,Huang P,Chen S,Li W,Xia LP,Xia X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Aug 13 00:00:00 EDT 2019
Epigenetically modulated FOXM1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer.
Molecular oncology
Zhou Z,Chen H,Xie R,Wang H,Li S,Xu Q,Xu N,Cheng Q,Qian Y,Huang R,Shao Z,Xiang M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2019
Aggregated and Hyperstable Damage-Associated Molecular Patterns Are Released During ER Stress to Modulate Immune Function.
Frontiers in cell and developmental biology
Andersohn A,Garcia MI,Fan Y,Thompson MC,Akimzhanov AM,Abdullahi A,Jeschke MG,Boehning D
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Sep 28 00:00:00 EDT 2020
Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells.
Stem cells and development
Fujii S,Yoshida S,Inagaki E,Hatou S,Tsubota K,Takahashi M,Shimmura S,Sugita S
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Jan 01 00:00:00 EST 2019
cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection.
International journal of molecular sciences
Li Q,Liu C,Yue R,El-Ashram S,Wang J,He X,Zhao D,Zhou X,Xu L
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Feb 19 00:00:00 EST 2019
Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation.
eLife
Bolger-Munro M,Choi K,Scurll JM,Abraham L,Chappell RS,Sheen D,Dang-Lawson M,Wu X,Priatel JJ,Coombs D,Hammer JA,Gold MR
17-0862-82 was used in Flow Cytometry to highlight a critical role for Arp2/3 complex-dependent actin remodeling in B cell responses to APC-bound antigens.
Mon Jun 03 00:00:00 EDT 2019
Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation.
eLife
Bolger-Munro M,Choi K,Scurll JM,Abraham L,Chappell RS,Sheen D,Dang-Lawson M,Wu X,Priatel JJ,Coombs D,Hammer JA,Gold MR
17-0862-82 was used in Flow Cytometry to highlight a critical role for Arp2/3 complex-dependent actin remodeling in B cell responses to APC-bound antigens.
Mon Jun 03 00:00:00 EDT 2019
Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction.
Frontiers in immunology
Fenninger F,Han J,Stanwood SR,Nohara LL,Arora H,Choi KB,Munro L,Pfeifer CG,Shanina I,Horwitz MS,Jefferies WA
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Oct 29 00:00:00 EDT 2020
Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer.
Journal of nanobiotechnology
Yuan SJ,Xu YH,Wang C,An HC,Xu HZ,Li K,Komatsu N,Zhao L,Chen X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Oct 17 00:00:00 EDT 2019
The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells.
Cell reports
Araujo LP,Maricato JT,Guereschi MG,Takenaka MC,Nascimento VM,de Melo FM,Quintana FJ,Brum PC,Basso AS
17-0862-82 was used in Flow Cytometry to uncover a suppressive role for the SNS in CNS autoimmunity while they identify potential targets for therapeutic intervention.
Tue Sep 17 00:00:00 EDT 2019
Mechanical stretch induces hair regeneration through the alternative activation of macrophages.
Nature communications
Chu SY,Chou CH,Huang HD,Yen MH,Hong HC,Chao PH,Wang YH,Chen PY,Nian SX,Chen YR,Liou LY,Liu YC,Chen HM,Lin FM,Chang YT,Chen CC,Lee OK
17-0862 was used in Flow cytometry/Cell sorting to study the mechanism by which mechanical stretch induces hair regeneration.
Wed Apr 03 00:00:00 EDT 2019
Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins.
Nature communications
Serradell MC,Rupil LL,Martino RA,Prucca CG,Carranza PG,Saura A,Fernández EA,Gargantini PR,Tenaglia AH,Petiti JP,Tonelli RR,Reinoso-Vizcaino N,Echenique J,Berod L,Piaggio E,Bellier B,Sparwasser T,Klatzmann D,Luján HD
17-0862 was used in Flow cytometry/Cell sorting to study the use of bioengineered virus-like particles with protozoan surface proteins in oral vaccination.
Mon Jan 21 00:00:00 EST 2019
Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity.
Immunity
Šestan M,Marinović S,Kavazović I,Cekinović Đ,Wueest S,Turk Wensveen T,Brizić I,Jonjić S,Konrad D,Wensveen FM,Polić B
17-0862 was used in Flow cytometry/Cell sorting to study how viral infection effects insulin resistance.
Tue Jul 17 00:00:00 EDT 2018
Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Immunity
Li X,Gadzinsky A,Gong L,Tong H,Calderon V,Li Y,Kitamura D,Klein U,Langdon WY,Hou F,Zou YR,Gu H
17-0862-82 was used in Flow Cytometry to show that deleting E3 ubiquitin ligases Cbl and Cbl-b (Cbls) in GC B cells results in the early exit of high-affinity antigen-specific B cells from the GC reaction and thus impaired clonal expansion.
Tue Mar 20 00:00:00 EDT 2018
Ginsenoside Rg3 Mitigates Atherosclerosis Progression in Diabetic apoE-/- Mice by Skewing Macrophages to the M2 Phenotype.
Frontiers in pharmacology
Guo M,Xiao J,Sheng X,Zhang X,Tie Y,Wang L,Zhao L,Ji X
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Oct 01 00:00:00 EDT 2020
Targeting macrophage and microglia activation with colony stimulating factor 1 receptor inhibitor is an effective strategy to treat injury-triggered neuropathic pain.
Molecular pain
Lee S,Shi XQ,Fan A,West B,Zhang J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Oct 22 00:00:00 EDT 2018
T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells.
Nature communications
Kim HR,Mun Y,Lee KS,Park YJ,Park JS,Park JH,Jeon BN,Kim CH,Jun Y,Hyun YM,Kim M,Lee SM,Park CS,Im SH,Jun CD
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri Sep 07 00:00:00 EDT 2018
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.
Nature communications
Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y
17-0862 was used in Flow cytometry/Cell sorting to assess the efficacy of a personalised cancer vaccine for eliciting postsurgical tumour specific-immunity.
Wed Apr 18 00:00:00 EDT 2018
BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.
Oncotarget
Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P
17-0862 was used in Flow cytometry/Cell sorting to evaluate the role played by BNIP3 in modulating the interface between B16-F10 melanoma cells and immune cells.
Tue Apr 03 00:00:00 EDT 2018
Lin-CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade.
Nature communications
Flores CT,Wildes TJ,Drake JA,Moore GL,Dean BD,Abraham RS,Mitchell DA
17-0862 was used in Flow cytometry/Cell sorting to elucidate a novel role for CCR2+ haematopoietic stem cells in overcoming brain tumour resistance to PD-1 checkpoint blockade and adoptive cellular therapy in multiple invasive brain tumour models.
Wed Oct 17 00:00:00 EDT 2018
Hif1α Deletion Limits Tissue Regeneration via Aberrant B Cell Accumulation in Experimental Pancreatitis.
Cell reports
Lee KE,Spata M,Maduka R,Vonderheide RH,Simon MC
Tue Jun 19 00:00:00 EDT 2018
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells.
Frontiers in immunology
Pan YG,Yu YL,Lin CC,Lanier LL,Chu CL
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Nov 20 00:00:00 EST 2019
Engaging the CD40-CD40L pathway augments T-helper cell responses and improves control of Mycobacterium tuberculosis infection.
PLoS pathogens
Sia JK,Bizzell E,Madan-Lala R,Rengarajan J
17-0862 was used in Flow cytometry/Cell sorting to determine the mechanism by which dendritic cells generate antigen specific T helper cells in response to Mycobacterium tuberculosis infection.
Tue Aug 01 00:00:00 EDT 2017
IRF6 Regulates Alternative Activation by Suppressing PPARγ in Male Murine Macrophages.
Endocrinology
Li C,Ying W,Huang Z,Brehm T,Morin A,Vella AT,Zhou B
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri Sep 01 00:00:00 EDT 2017
Discrimination of the heterogeneity of bone marrow‑derived dendritic cells.
Molecular medicine reports
Wang J,Dai X,Hsu C,Ming C,He Y,Zhang J,Wei L,Zhou P,Wang CY,Yang J,Gong N
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Nov 01 00:00:00 EDT 2017
Calreticulin is an effective immunologic adjuvant to tumor-associated antigens.
Experimental and therapeutic medicine
Wang J,Gao ZP,Qin S,Liu CB,Zou LL
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sun Oct 01 00:00:00 EDT 2017
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Feb 06 00:00:00 EST 2017
Identification of 14-dehydroergosterol as a novel anti-inflammatory compound inducing tolerogenic dendritic cells.
Scientific reports
Ano Y,Ikado K,Shindo K,Koizumi H,Fujiwara D
Tue Oct 24 00:00:00 EDT 2017
Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia.
Cancer discovery
Lee KE,Spata M,Bayne LJ,Buza EL,Durham AC,Allman D,Vonderheide RH,Simon MC
17-0862 was used in Flow cytometry/Cell sorting to investigate the effects of tumour hypoxia on the initiation and progression of pancreatic ductal adenocarcinoma.
Tue Mar 01 00:00:00 EST 2016
MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4.
Frontiers in immunology
Zhao J,Chen C,Guo M,Tao Y,Cui P,Zhou Y,Qin N,Zheng J,Zhang J,Xu L
17-0862 was used in Flow cytometry/Cell sorting to study the role of microRNA-7 in acute lung injury, allowing the development of new therapeutic strategies against inflammatory lung disease.
Wed Mar 16 00:00:00 EDT 2022
Repulsive guidance molecule a blockade exerts the immunoregulatory function in DCs stimulated with ABP and LPS.
Human vaccines & immunotherapeutics
Xu X,Gao Y,Zhai Z,Zhang S,Shan F,Feng J
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Aug 02 00:00:00 EDT 2016
Metformin Inhibits Advanced Glycation End Products-Induced Inflammatory Response in Murine Macrophages Partly through AMPK Activation and RAGE/NFκB Pathway Suppression.
Journal of diabetes research
Zhou Z,Tang Y,Jin X,Chen C,Lu Y,Liu L,Shen C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Jun 06 00:00:00 EDT 2017
Evaluation of the irritancy and hypersensitivity potential following topical application of didecyldimethylammonium chloride.
Journal of immunotoxicology
Anderson SE,Shane H,Long C,Lukomska E,Meade BJ,Marshall NB
17-0862 was used in Flow cytometry/Cell sorting to investigate the irritancy and hypersensivity potential of didecyldimethylammonium chloride (DDAC).
Fri Jul 01 00:00:00 EDT 2016
CD80 and CD86 knockdown in dendritic cells regulates Th1/Th2 cytokine production in asthmatic mice.
Experimental and therapeutic medicine
Li JG,DU YM,Yan ZD,Yan J,Zhuansun YX,Chen R,Zhang W,Feng SL,Ran PX
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Mar 01 00:00:00 EST 2016
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions.
Scientific reports
Ying W,Tseng A,Chang RC,Wang H,Lin YL,Kanameni S,Brehm T,Morin A,Jones B,Splawn T,Criscitiello M,Golding MC,Bazer FW,Safe S,Zhou B
17-0862 was used in Flow cytometry/Cell sorting to demonstrate a role for miR-150 in regulating B cell functions in adipose tissue.
Mon Feb 01 00:00:00 EST 2016
CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control.
Oncoimmunology
Veinotte L,Gebremeskel S,Johnston B
17-0862 was used in Flow cytometry/Cell sorting to study the co-stimulatory role of CXCR6/CXCL16 interactions in glycolipid-dependent invariant natural killer T (iNKT) cell activation and tumour control, showing that CXCL16-positive dendritic cells enhance iNKT cell-dependent IFNγ production and tumor control.
Wed Jun 01 00:00:00 EDT 2016
Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury.
Frontiers in cellular neuroscience
Hellström Erkenstam N,Smith PL,Fleiss B,Nair S,Svedin P,Wang W,Boström M,Gressens P,Hagberg H,Brown KL,Sävman K,Mallard C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sat Jan 29 00:00:00 EST 2022
D-Alanylation of Teichoic Acids and Loss of Poly-N-Acetyl Glucosamine in Staphylococcus aureus during Exponential Growth Phase Enhance IL-12 Production in Murine Dendritic Cells.
PloS one
Lund LD,Ingmer H,Frøkiær H
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Jul 14 00:00:00 EDT 2016
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Thu Jan 01 00:00:00 EST 2015
Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.
Immunity
Bruttger J,Karram K,Wörtge S,Regen T,Marini F,Hoppmann N,Klein M,Blank T,Yona S,Wolf Y,Mack M,Pinteaux E,Müller W,Zipp F,Binder H,Bopp T,Prinz M,Jung S,Waisman A
17-0862 was used in Flow cytometry/Cell sorting to study how microglia have the potential for efficient self-renewal without the contribution of peripheral myeloid cells, and IL-1R signaling participates in this restorative proliferation process.
Tue Jul 21 00:00:00 EDT 2015
MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.
The Journal of clinical investigation
Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B
17-0862 was used in Flow cytometry/Cell sorting to investigate the regulatory network of polarised activation of adipose tissue macrophages.
Mon Nov 02 00:00:00 EST 2015
Towards programming immune tolerance through geometric manipulation of phosphatidylserine.
Biomaterials
Roberts RA,Eitas TK,Byrne JD,Johnson BM,Short PJ,McKinnon KP,Reisdorf S,Luft JC,DeSimone JM,Ting JP
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2015
Antitumor immunity triggered by melphalan is potentiated by melanoma cell surface-associated calreticulin.
Cancer research
Dudek-Perić AM,Ferreira GB,Muchowicz A,Wouters J,Prada N,Martin S,Kiviluoto S,Winiarska M,Boon L,Mathieu C,van den Oord J,Stas M,Gougeon ML,Golab J,Garg AD,Agostinis P
17-0862 was used in Flow cytometry/Cell sorting to illustrate how melphalan triggers inflammatory cell death that can be leveraged by immunomodulators.
Wed Apr 15 00:00:00 EDT 2015
Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells.
Journal of immunology (Baltimore, Md. : 1950)
Vaeth M,Zee I,Concepcion AR,Maus M,Shaw P,Portal-Celhay C,Zahra A,Kozhaya L,Weidinger C,Philips J,Unutmaz D,Feske S
17-0862 was used in Flow cytometry/Cell sorting to investigate the role of STIM1, STIM2 and SOCE on effector functions of macrophages and dendritic cells, and how these affect CRAC channel inhibition.
Sat Aug 01 00:00:00 EDT 2015
Triclosan Induces Thymic Stromal Lymphopoietin in Skin Promoting Th2 Allergic Responses.
Toxicological sciences : an official journal of the Society of Toxicology
Marshall NB,Lukomska E,Long CM,Kashon ML,Sharpnack DD,Nayak AP,Anderson KL,Jean Meade B,Anderson SE
17-0862 was used in Flow cytometry/Cell sorting to examine the effects of dermal triclosan exposure on the skin and lymph nodes of mice and in a human skin model to identify mechanisms for augmenting allergic responses.
Tue Sep 01 00:00:00 EDT 2015
Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.
Molecular medicine reports
Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Injectable cryogel-based whole-cell cancer vaccines.
Nature communications
Bencherif SA,Warren Sands R,Ali OA,Li WA,Lewin SA,Braschler TM,Shih TY,Verbeke CS,Bhatta D,Dranoff G,Mooney DJ
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Aug 12 00:00:00 EDT 2015
Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development.
Scientific reports
Frodermann V,van Duijn J,van Pel M,van Santbrink PJ,Bot I,Kuiper J,de Jager SC
17-0862 was used in Flow cytometry/Cell sorting to study how MSC treatment affects not only inflammatory responses but also significantly reduces dyslipidaemia in mice.
Thu Oct 22 00:00:00 EDT 2015
Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4).
The Journal of biological chemistry
Tsuji R,Koizumi H,Aoki D,Watanabe Y,Sugihara Y,Matsushita Y,Fukushima K,Fujiwara D
17-0862 was used in Flow cytometry/Cell sorting to investigate the role of lignin-rich enzyme lignin in dendritic cells.
Fri Feb 13 00:00:00 EST 2015
Loss of Gadkin Affects Dendritic Cell Migration In Vitro.
PloS one
Schachtner H,Weimershaus M,Stache V,Plewa N,Legler DF,Höpken UE,Maritzen T
17-0862 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which Gadkin and ARP2/3 regulate dendritic cell motility and migration.
Mon Jun 20 00:00:00 EDT 2016
Tick sialostatins L and L2 differentially influence dendritic cell responses to Borrelia spirochetes.
Parasites & vectors
Lieskovská J,Páleníková J,Langhansová H,Campos Chagas A,Calvo E,Kotsyfakis M,Kopecký J
17-0862 was used in Flow cytometry/Cell sorting to investigate the impact of cystatins on Borrelia growth in vivo.
Fri May 15 00:00:00 EDT 2015
Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii.
PLoS pathogens
Dupont CD,Christian DA,Selleck EM,Pepper M,Leney-Greene M,Harms Pritchard G,Koshy AA,Wagage S,Reuter MA,Sibley LD,Betts MR,Hunter CA
17-0862 was used in Flow cytometry/Cell sorting to identify a critical role for actively infected host cells in initiating T. gondii-specific CD4+ and CD8+ T cell responses.
Tue Apr 01 00:00:00 EDT 2014
Boosting functional avidity of CD8+ T cells by vaccinia virus vaccination depends on intrinsic T-cell MyD88 expression but not the inflammatory milieu.
Journal of virology
Hu Z,Wang J,Wan Y,Zhu L,Ren X,Qiu S,Ren Y,Yuan S,Ding X,Chen J,Qiu C,Sun J,Zhang X,Xiang J,Qiu C,Xu J
17-0862 was used in Flow cytometry/Cell sorting to investigate how vaccinia-vectored vaccine (VACV) shapes the properties of memory CD8+ T cells, showing that it depends on intrinsic T-cell MyD88 expression.
Thu May 01 00:00:00 EDT 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Mon Jan 05 00:00:00 EST 2015
BCG vaccine mediated reduction in the MHC-II expression of macrophages and dendritic cells is reversed by activation of Toll-like receptors 7 and 9.
Cellular immunology
Bakhru P,Sirisaengtaksin N,Soudani E,Mukherjee S,Khan A,Jagannath C
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
Lung dendritic cells undergo maturation and polarization towards a T helper type 2-stimulating phenotype in a mouse model of asthma: Role of nerve growth factor.
Experimental and therapeutic medicine
Qin Q,Wang Z,Pan P,Cao Z,Xia Q,Tan H,Hu C
Sat Nov 01 00:00:00 EDT 2014
Amelioration of experimental autoimmune encephalomyelitis by the quinoline-3-carboxamide paquinimod: reduced priming of proinflammatory effector CD4(+) T cells.
The American journal of pathology
Helmersson S,Sundstedt A,Deronic A,Leanderson T,Ivars F
17-0862 was used in Flow cytometry/Cell sorting to show that paquinimod treatment during the first 5 days after induction of experimental autoimmune encephalomyelitis eases disease symptoms.
Wed May 01 00:00:00 EDT 2013
SWAP-70 restricts spontaneous maturation of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Ocaña-Morgner C,Götz A,Wahren C,Jessberger R
17-0862 was used in Flow cytometry/Cell sorting to study the mechanisms and signals that produce mature DCs.
Sat Jun 01 00:00:00 EDT 2013
Histone deacetylase inhibitors suppress immune activation in primary mouse microglia.
Journal of neuroscience research
Kannan V,Brouwer N,Hanisch UK,Regen T,Eggen BJ,Boddeke HW
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2013
Resistance to malaria by enhanced phagocytosis of erythrocytes in LMP7-deficient mice.
PloS one
Duan X,Imai T,Chou B,Tu L,Himeno K,Suzue K,Hirai M,Taniguchi T,Okada H,Shimokawa C,Hisaeda H
17-0862 was used in Flow cytometry/Cell sorting to study how RBCs of LMP7-deficient mice were more likely to deform in response to infection with malaria parasites.
Tue Sep 17 00:00:00 EDT 2013
Neutralization of TSLP inhibits airway remodeling in a murine model of allergic asthma induced by chronic exposure to house dust mite.
PloS one
Chen ZG,Zhang TT,Li HT,Chen FH,Zou XL,Ji JZ,Chen H
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Tue Aug 20 00:00:00 EDT 2013
Enhancement of CTLs induced by DCs loaded with ubiquitinated hepatitis B virus core antigen.
World journal of gastroenterology
Chen JH,Yu YS,Chen XH,Liu HH,Zang GQ,Tang ZH
17-0862 was used in Flow cytometry/Cell sorting to demonstrate a method for the HBV-induced augmentation of the CTL response.
Wed Mar 28 00:00:00 EDT 2012
Novel murine dendritic cell lines: a powerful auxiliary tool for dendritic cell research.
Frontiers in immunology
Fuertes Marraco SA,Grosjean F,Duval A,Rosa M,Lavanchy C,Ashok D,Haller S,Otten LA,Steiner QG,Descombes P,Luber CA,Meissner F,Mann M,Szeles L,Reith W,Acha-Orbea H
17-0862 was used in Flow cytometry/Cell sorting to report the generation of new murine DC lines, named MutuDC, originating from cultures of splenic CD8α conventional DC (cDC) tumours.
Tue Nov 20 00:00:00 EST 2012
Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice.
PloS one
Kamphuis T,Meijerhof T,Stegmann T,Lederhofer J,Wilschut J,de Haan A
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Wed Sep 19 00:00:00 EDT 2012
Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.
The Journal of clinical investigation
Kastenmüller K,Wille-Reece U,Lindsay RW,Trager LR,Darrah PA,Flynn BJ,Becker MR,Udey MC,Clausen BE,Igyarto BZ,Kaplan DH,Kastenmüller W,Germain RN,Seder RA
17-0862 was used in Flow cytometry/Cell sorting to investigate the requirements for a vaccine to induce protective multifunctional T cell immunity in vivo.
Sun May 01 00:00:00 EDT 2011
Elevated epidermal ornithine decarboxylase activity suppresses contact hypersensitivity.
The Journal of investigative dermatology
Keough MP,Hayes CS,DeFeo K,Gilmour SK
17-0862 was used in Flow cytometry/Cell sorting to suggest that the immunosuppression promoted by increased epidermal ODC is mediated by a reduction in cytokine levels, which suppresses DC migration and reduces immune cell infiltration to the site of hapten application.
Sat Jan 01 00:00:00 EST 2011
UV exposure boosts transcutaneous immunization and improves tumor immunity: cytotoxic T-cell priming through the skin.
The Journal of investigative dermatology
Stein P,Rechtsteiner G,Warger T,Bopp T,Fuhr T,Prüfer S,Probst HC,Stassen M,Langguth P,Schild H,Radsak MP
17-0862 was used in Flow Cytometry to explore the effects of ultraviolet irradiation on imiquimod-based transcutaneous immunisation.
Sat Jan 01 00:00:00 EST 2011
Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Miranda-Hernandez S,Gerlach N,Fletcher JM,Biros E,Mack M,Körner H,Baxter AG
17-0862 was used in Flow cytometry/Cell sorting to examine the effects of targeted deletions of specific TLRs on the induction of toxin-induced autoimmune encephalomyelitis.
Fri Jul 15 00:00:00 EDT 2011
Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.
PloS one
Fuertes Marraco SA,Scott CL,Bouillet P,Ives A,Masina S,Vremec D,Jansen ES,O'Reilly LA,Schneider P,Fasel N,Shortman K,Strasser A,Acha-Orbea H
17-0862 was used in Flow cytometry/Cell sorting to elucidate the possible apoptotic mechanisms that control activated dendritic cell lifespan in response to PAMPs.
Fri Sep 30 00:00:00 EDT 2011
IL-37 is a fundamental inhibitor of innate immunity.
Nature immunology
Nold MF,Nold-Petry CA,Zepp JA,Palmer BE,Bufler P,Dinarello CA
17-0862 was used in Flow cytometry/Cell sorting to determine the function of interleukin 37.
Mon Nov 01 00:00:00 EDT 2010
Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs.
Molecular therapy : the journal of the American Society of Gene Therapy
Toscano MG,Delgado M,Kong W,Martin F,Skarica M,Ganea D
17-0862 was used in Flow cytometry/Cell sorting to characterise the phenotype and therapeutic effects of transduced LentiVIP-dendritic cells in models of EAE and CLP, showing that they differentiate into VIP-secreting tolerogenic-like DCs.
Sat May 01 00:00:00 EDT 2010
Dendritic cells continue to capture and present antigens after maturation in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Drutman SB,Trombetta ES
17-0862 was used in Flow cytometry/Cell sorting to study the dynamics of Ag capture and presentation in situ, showing that dendritic cells continue to capture and present antigens after maturation.
Sun Aug 15 00:00:00 EDT 2010
Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells.
Journal of immunology (Baltimore, Md. : 1950)
Tomihara K,Guo M,Shin T,Sun X,Ludwig SM,Brumlik MJ,Zhang B,Curiel TJ,Shin T
17-0862 was used in Flow cytometry/Cell sorting to investigate CD11b(+)Gr-1(+) cells found in epithelial ovarian cancer-bearing mice, which are induced by ovarian cancer cells and undergo antigen-specific immunity and cross-priming.
Tue Jun 01 00:00:00 EDT 2010
CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection.
Infection and immunity
Eppert BL,Motz GT,Wortham BW,Flury JL,Borchers MT
17-0862 was used in Flow cytometry/Cell sorting to investigate the roles of CCR7 in the host defense against pulmonary infection, showing that CCR7 deficiency leads to leukocyte activation and increased infection clearance.
Sat May 01 00:00:00 EDT 2010
Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen.
Journal of immunology (Baltimore, Md. : 1950)
Maroof A,Beattie L,Kirby A,Coles M,Kaye PM
17-0862 was used in Flow cytometry/Cell sorting to study how inflammation-matured DCs can induce Ag-independent T cell proliferation.
Tue Dec 01 00:00:00 EST 2009
Polymeric linear Peptide chimeric vaccine-induced antimalaria immunity is associated with enhanced in vitro antigen loading.
Infection and immunity
Silva-Flannery LM,Cabrera-Mora M,Dickherber M,Moreno A
17-0862 was used in Flow cytometry/Cell sorting to investigate the antigenic properties of polymeric antimalarial peptides, showing that immunity is associated with enhanced in vitro antigen loading.
Fri May 01 00:00:00 EDT 2009
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Nature immunology
Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M
Published figure using CD86 (B7-2) monoclonal antibody (Product # 17-0862-82) in Flow Cytometry
Fri Aug 01 00:00:00 EDT 2008
-Flow-20170216130641.jpg?time=20240507 "CD86 (B7-2) Antibody in Flow Cytometry (Flow)")
-Flow-20170216130641.jpg?time=20240507)
-Flow-20170216130641.jpg?time=20240507?time=20240507 "CD86 (B7-2) Antibody (17-0862-82) in Flow")
