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Immunogen sequence: GLRWTPKSP LDPDSGLLSC TLPNGFGGQS GPEGERSLAP PDASILISNV CSIGDHVAQE LFQGSDLGMA EEAERPGEKA GQHSPLREEH VTCVQSILDE FLQTYGSLIP LSTDEVVEKL EDIFQQEFST PSRKGLVLQL IQSYQRMPGN AMVRGFRVAY KRHVLTMDDL GTLYGQNWLN DQVMNMYGDL VMDTVPEKVH FFNSFFYDKL RTKGYDGVKR WTKNVDIFNK ELLLIPIHLE VHWSLISVDV RRRTITYFDS QRTLNRRCPK HIAKYLQAEA VKKDRLDFHQ GWKGYFKMNV ARQNNDSDCG AFVLQYCKHL ALSQPFSFTQ QDMPKLRRQI YKELCHCKLT V (225-574 aa encoded by BC080658)
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZP586K0919; DKFZp762A152; Sentrin-specific protease 3; sentrin/SUMO-specific protease 3; Sentrin/SUMO-specific protease SENP3; SUMO-1-specific protease 3; SUMO/sentrin specific peptidase 3; SUMO/sentrin specific protease 3
基因别名: SENP3; SMT3IP1; SSP3; SUSP3; Ulp1
UniProt ID: (Human) Q9H4L4
Entrez Gene ID: (Human) 26168, (Rat) 303245
分子生物学功能: protease