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产品信息
PA5-142391
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-NGGHPSPSRNYGDGT.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2933039
产品详细信息
Additional Information: This antibody is expected to recognise the reported isoforms a and b (NP_001077431.1; NP_003190.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
靶标信息
TCF4 is transcription factor 4, a basic helix-turn-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG')-a motif first identified in immunoglobulin enhancers. This gene is expressed predominantly in pre-B-cells, although it is found in other tissues as well. Defects in this gene are a cause of Pitt-Hopkins syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHb19; Class B basic helix-loop-helix protein 19; E2 2; Immunoglobulin transcription factor 2; ITF 2; ITF-2; MGC149723; MGC149724; SEF 2; SEF-2; SEF2 1; SEF2 1A; SEF2 1B; SL3-3 enhancer factor 2; TCF 4; TCF-4; Transcription factor 4; transcription factor 4, isoform C; transcription factor 4, isoform D; transcription factor 4, isoform E; transcription factor 4, isoform L; transcription factor 4, isoform M; transcription factor 4, isoform R
基因别名: BHLHB19; E2-2; FECD3; ITF-2; ITF2; PTHS; SEF-2; SEF2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; TCF-4; TCF4
UniProt ID: (Human) P15884
Entrez Gene ID: (Human) 6925
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, TFIIB-class binding
TFIIB-class transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
identical protein binding
protein homodimerization activity
bHLH transcription factor binding
protein heterodimerization activity
E-box binding
basic helix-loop-helix transcription factor
