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SEQ digital PCR analytical assay solutions
Successful approval of biologics depends on robust product characterization, helping to ensure the safety, purity, and potency of the final drug product. SEQ digital PCR solutions include assay kits for both residual host cell DNA quantitation and viral vector titer and quantitation, with performance that meets or exceeds regulatory guidelines. These kits have been designed and developed to ensure the highest levels of sensitivity and specificity and have been internally validated on the Applied Biosystems QuantStudio Absolute Q Digital PCR System.
SEQ dPCR kits include:
| TaqMan-based primer/probe sets | TaqMan dPCR Master Mix | Negative control | Genomic DNA standard | DNA dilution buffer |
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| Optional for some dPCR kits | ||||
ResDNASEQ digital PCR residual DNA quantitation
The portfolio of Applied Biosystems resDNASEQ Residual DNA Kits for digital PCR continues to grow, providing coverage for many commonly used cell lines in biotherapeutic development. These kits are built upon the foundation of our resDNASEQ qPCR assays, which have earned a reputation for their exceptional quality and performance. As a result, they have become a trusted and widely adopted solution in routine use at leading biopharmaceutical companies. We are excited to now deliver the same level of quality and performance for use with digital PCR.
resDNASEQ Quantitative
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resDNASEQ Quantitative
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resDNASEQ Quantitative
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resDNASEQ Quantitative
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resDNASEQ
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| The Applied Biosystems resDNASEQ dPCR E1A DNA Fragment Length Kit can be used in combination with the resDNASEQ dPCR HEK293 DNA Kit to measure the length of residual E1A DNA fragments that are transformed into the HEK293 cell line. The workflow can use the same sample as the resDNASEQ dPCR HEK293 DNA Kit. |  |
Residual DNA and fragment sizing in HEK-based applications
Fast Facts: Robust quantitation of residual host cell and
plasmid DNA & oncogenic fragments in HEK-based viral vector manufacturing
ViralSEQ digital PCR Viral Titer Determination
Cell and gene therapies rely on various viral vectors to transfer transgenes to target cells. However, accurately regulating the concentration of these therapeutic substances can be challenging. We help address this challenge with Applied Biosystems ViralSEQ dPCR Viral Titer Assay kits, specifically designed for precise and consistent virus quantitation and characterization. By enabling reliable and reproducible results, our ViralSEQ dPCR assay kits help empower you to optimize your cell and gene therapy protocols and enhance the safety and efficacy of your viral vector-based treatments.
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