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Gene therapy: It’s in our DNA.

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Because saving lives is in yours.

With Thermo Fisher Scientific, you have the support to push your therapeutic development strategies a step further. We offer a suite of scalable and robust solutions for all stages of the gene therapy workflow, from development through commercialization, to help you accelerate your development and document regulatory standards with confidence. With our help, you can bring your discovery to life and accelerate delivery of live-saving, breakthrough therapies.

Solutions for every stage of the gene therapy workflow:

Why Thermo Fisher Scientific?

With Thermo Fisher Scientific, you can save more lives, faster.

  • Years of experience: By working with us, you’ll leverage our years of experience as a world leader in serving science.
  • Support at every stage: Our goal is to support you at every stage of the gene therapy development process and to provide you with reliable tools, support, and scientific experience to assist you in bringing your therapies to regulatory review.
  • Scalable and compatible: Our products are scalable and compatible with the equipment you already have, which saves time and money, allowing you to focus on what's truly important: saving lives.


Cell and gene therapy industry perspectives

Brandon Pence, Thermo Fisher Scientific

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    Products by workflow

     Plasmid development and production Plasmid development and production

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    Achieve faster process development with tools designed to scale production and isolate, purify, and extract stable, quality plasmid DNA.

    Featured products

    Support upstream process intensification and provide nutritional benefits for plasmid DNA production.

    The only ready-to-use, real-time qPCR system to help process development and test product for impurities from residual host cell DNA and from residual kanamycin resistance gene plasmid.

    Bacto CD Supreme Fermentation Production Medium (FPM) is a dehydrated powder medium (DPM) designed specifically for fermentation applications to support high cell density cultures of Escherichia coli.


    Cell expansion Cell expansion

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    As the highest volume media manufacturer, we can help you increase productivity, mitigate supply risks, and improve efficiency.

    Featured products

    Every cell culture project is unique. Combine the reliability of Gibco products with our nimble, responsive custom service.

    An efficient bioreactor solution that will easily integrate into your current processes, as well as future scale-up processes.

    Scale up and adapt to suit specific process and application goals with this innovative, open-architecture, cost-effective controller.


    Plasmid transfection Plasmid transfection

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    To achieve efficient gene transfer by transfection, plasmid DNA can be complexed with lipid reagents to mediate efficient delivery into the cell's nucleus. We offer an array of plasmid transfection products.

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    Ready-to-use single-use flexible container systems for critical liquid handling applications in biopharmaceutical manufacturing operations.

    Bring your processes together seamlessly with an extensive range of catalog and customized fluid transfer products.

    Transfection reagents optimized for efficiency, viability, and reproducibility across a broad range of cell types.


    Viral vector production Viral vector production

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    No matter the production scale or cell lines used, we can supply you with state-of-the-art products across your upstream viral vector production workflow.

    Featured products

    A scalable and high-yield lentiviral vector production platform in a chemically defined, serum-free environment.

     

    Purification Purification

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    Browse our innovative chromatography solutions specifically designed to improve the downstream purification of viral vectors, including the Adeno-Associated Virus (AAV), lentivirus, and AdenovirusType 5 (Adv5), as well as mRNA.

    Featured products

    Engineered to address the high selectivity and capacity requirements of large-scale downstream purification for a broad range of naturally occurring and synthetic AAV serotypes.

    Developed to address the selectivity and capacity requirements for large-scale downstream purification of mRNA.

    We have access to a global network of suppliers and a comprehensive and customizable portfolio covering many chemical categories.


    QC lot release and risk mitigation QC lot release and risk mitigation

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    We're here to support your implementation of our bioproduction solution to align with regulatory requirements, from evaluation through validation and regulatory review.

    Featured products

    Designed to deliver actionable results for detection of over 90 species of Mycoplasma in fewer than four hours.

    The only ready-to-use, real-time qPCR system to help process development and test product for impurities from residual host cell DNA and from residual kanamycin resistance gene plasmid.

    The ViralSEQ Sf-Rhabdovirus Kit for rapid, sensitive quantitation using real-time PCR with integrated DNA purification.


    Bulk storage, fill, and finish Bulk storage, fill, and finish

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    Thermo Fisher provides drug product fill, finish, and storage solutions, including sterile container systems for therapy delivery.

    Featured products

    Developed to meet bioproduction workflow needs. These BPCs provide improved ease of use, high reliability, and quality.

    With the capabilities to generate a broad combination of cleanliness parameters and certifications, coupled with custom packaging options, we can meet your precise specifications and requirements.

    Critical to lot-release are regulatory required contaminant and impurity testing.  PrepSEQ kits ensure consistent, reliable recovery of DNA and RNA to facilitate validation of qPCR-based safety and quality testing.


    Scientist analyzes DNA gel used in genetics.

    Our products in action

    Case studies and articles spotlighting Thermo Fisher Scientific gene therapy solutions.

    Process liquid and buffer preparation services

    Outsourcing trusted-weight dry powder buffers to support expansion of a major pharmaceutical manufacturer’s gene therapy division.

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    AAV vector process development: achieving high purity and high yield

    Expert roundtable: experiences from the frontline.

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    Upstream and downstream solutions for AAV manufacturing

    Identifying opportunities for process optimization of AAV manufacturing workflows to support scalable viral vector manufacturing to meet increasing demand.

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    U.S. approval of three rapid microbiological methods for MACI product release

    An autologous cell therapy product release.

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    Optimized cell culture for the bench and beyond

    Supporting the commercialization of cell culture processes with a simple and effective solution: the Thermo Scientific Nunc Cell Factory system.

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    Optimizing the HyPerforma Single-Use Bioreactor for adherent cell culture on microcarriers

    Studying the performance of 50 L and 250 L HyPerforma S.U.B.s.

    Learn more ›

    生物工艺资源

    点击以下链接获取产品手册、培训视频、手机App和更多资源。

    For research use or further manufacturing. Not for use in diagnostic procedures.