Antibodies that detect LDLR can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target LDLR in Human, Mouse, Rat, Bovine and Hamster samples. Our LDLR monoclonal, polyclonal and...Antibodies that detect LDLR can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target LDLR in Human, Mouse, Rat, Bovine and Hamster samples. Our LDLR monoclonal, polyclonal and recombinant monoclonal...Antibodies that detect LDLR can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target LDLR in Human, Mouse, Rat, Bovine and Hamster samples. Our LDLR monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Chicken. These antibodies have been verified by Knockdown, Relative expression and Cell treatment to confirm specificity to LDLR. Find the LDLR antibody that fits your needs. Choose from 1 of 44 LDLR antibodies, which have been validated in experiments with 125 publications and 119 images featured in our data gallery.
Browse primary antibodies for WB,...
Antibodies that detect LDLR can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target LDLR in Human, Mouse, Rat, Bovine and Hamster samples. Our LDLR monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat and Chicken. These antibodies have been verified by Knockdown, Relative expression and Cell treatment to confirm specificity to LDLR. Find the LDLR antibody that fits your needs. Choose from 1 of 44 LDLR antibodies, which have been validated in experiments with 125 publications and 119 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in the LDL-R gene cause the autosomal dominant disorder, familial hypercholesterolemia. Along with SCARB1, CLDN1, and the tetraspanin superfamily member CD81, LDL-R has been reported to be an entry factor for the Hepatitis C virus. At least three isoforms of LDL-R are known to exist.
同义词
FH; FHC; Hlb301; I79_005860; LDL receptor; LDLA; LDLCQ2; LDLR; ldl-r; LDLRA; low density lipoprotein receptor; low density lipoprotein receptor protein; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3
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