PAI1 Antibodies

Antibodies that detect PAI1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target PAI1 in Human, Mouse, Rat and Porcine samples. Our PAI1 polyclonal, recombinant monoclonal and... Antibodies that detect PAI1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target PAI1 in Human, Mouse, Rat and Porcine samples. Our PAI1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in... Antibodies that detect PAI1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target PAI1 in Human, Mouse, Rat and Porcine samples. Our PAI1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse, Alpaca and Goat. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to PAI1. Find the PAI1 antibody that fits your needs. Choose from 1 of 36 PAI1 antibodies, which have been validated in experiments with 75 publications and 76 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other... Antibodies that detect PAI1 can be used in several scientific applications, including Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry and Flow Cytometry. These antibodies target PAI1 in Human, Mouse, Rat and Porcine samples. Our PAI1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Mouse, Alpaca and Goat. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to PAI1. Find the PAI1 antibody that fits your needs. Choose from 1 of 36 PAI1 antibodies, which have been validated in experiments with 75 publications and 76 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

PAI1 (plasminogen activator inhibitor 1) belongs to serine protease inhibitor superfamily, and is the principal inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA). Platelets are the main source of the circulating PAI11, but it is synthesized and secreted by many tissue and cell types, including fibroblasts, smooth muscle cells, endothelial cells, hepatocytes, and inflammatory cells. Expression of PAI11 can be regulated at the transcriptional level by many factors including growth factors, cytokines, hormones, inflammatory factors, glucose or lipid metabolites, vascular tone regulating factors, chemicals, and other environmental or physical factors. PAI1 is present at increased levels in various disease states, and has been linked to an increased occurrence of thrombosis in obesity, thrombophilia and the metabolic syndrome. Defects in PAI-1 are characterized by abnormal bleeding. PAI1 mediates inhibition of fibrinolysis by inhibiting the activity of plasminogen activator, and may promote neuronal survival. Other defects in PAI1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency). Alternatively spliced transcript variants encoding different isoforms of PAI1 have been found.

同义词

Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1

PAI1 Antibodies

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